Gene: Plekha7 (pleckstrin homology domain containing A7) Rattus norvegicus
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Symbol: Plekha7
Name: pleckstrin homology domain containing A7
Description: ENCODES a protein that exhibits delta-catenin binding (ortholog); INVOLVED IN epithelial cell-cell adhesion (ortholog); zonula adherens maintenance (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ASSOCIATED WITH decreased susceptibility to hypertension; decreased systemic vascular resistance; decreased urine albumin level; ASSOCIATED WITH Cardiac Fibrosis; Glomerulosclerosis; glomerulosclerosis; FOUND IN cell junction (ortholog); centrosome (ortholog); cytosol (ortholog); INTERACTS WITH bisphenol A; vinclozolin; (-)-epigallocatechin 3-gallate (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC499249; pleckstrin homology domain containing, family A member 7; pleckstrin homology domain-containing family A member 7; RGD1304650; similar to Plekha7 protein
Orthologs:
Homo sapiens (human) : PLEKHA7 (pleckstrin homology domain containing A7)  HGNC  AGR
Mus musculus (house mouse) : Plekha7 (pleckstrin homology domain containing, family A member 7)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Plekha7 (pleckstrin homology domain containing A7)
Pan paniscus (bonobo/pygmy chimpanzee) : PLEKHA7 (pleckstrin homology domain containing A7)
Canis lupus familiaris (dog) : PLEKHA7 (pleckstrin homology domain containing A7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plekha7 (pleckstrin homology domain containing A7)
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Allele / Splice: Plekha7em1Mcwi   Plekha7em4Mcwi  
Genetic Models: SS-Plekha7em4Mcwi SS-Plekha7em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01185,427,600 - 185,493,985 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01192,397,589 - 192,463,974 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41174,249,022 - 174,316,226 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1168,231,482 - 168,298,068 (-)NCBICelera
Cytogenetic Map1q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Plekha7
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1598216
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2017-11-14
Status: ACTIVE