Vom2r71 (vomeronasal 2 receptor, 71) - Rat Genome Database

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Pathways
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Gene: Vom2r71 (vomeronasal 2 receptor, 71) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r71
Name: vomeronasal 2 receptor, 71
RGD ID: 1597426
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane; INTERACTS WITH 6-propyl-2-thiouracil; cadmium dichloride; Monobutylphthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100911147; LOC689060; similar to vomeronasal 2, receptor, 1; vomeronasal 2, receptor 71; vomeronasal type-2 receptor 116-like; vomeronasal type-2 receptor 26-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814706,671 - 731,019 (-)NCBIGRCr8
mRatBN7.214691,705 - 716,053 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14691,705 - 716,053 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.014900,696 - 923,918 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,606,503 - 71,630,403 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl14900,696 - 973,231 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014900,797 - 924,019 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414893,641 - 917,991 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1463,878 - 87,853 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17382427  


Genomics

Variants

.
Variants in Vom2r71
31 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:190
Count of miRNA genes:88
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000029752, ENSRNOT00000037286, ENSRNOT00000045085, ENSRNOT00000049544
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000045085   ⟹   ENSRNOP00000043336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl171,606,503 - 71,630,403 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000049544   ⟹   ENSRNOP00000041059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl14900,696 - 973,231 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115443   ⟹   ENSRNOP00000093961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl14691,705 - 716,053 (-)Ensembl
RefSeq Acc Id: NM_001419359   ⟹   NP_001406288
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814706,671 - 731,019 (-)NCBI
mRatBN7.214691,705 - 716,053 (-)NCBI
RefSeq Acc Id: NM_001419360   ⟹   NP_001406289
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814706,671 - 731,019 (-)NCBI
mRatBN7.214691,705 - 716,053 (-)NCBI
RefSeq Acc Id: XM_039092460   ⟹   XP_038948388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814706,671 - 731,019 (-)NCBI
mRatBN7.214691,705 - 716,053 (-)NCBI
RefSeq Acc Id: XM_039092461   ⟹   XP_038948389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814706,671 - 731,019 (-)NCBI
mRatBN7.214691,705 - 716,053 (-)NCBI
RefSeq Acc Id: XM_063273634   ⟹   XP_063129704
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814706,671 - 731,019 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000041059   ⟸   ENSRNOT00000049544
RefSeq Acc Id: XP_038948389   ⟸   XM_039092461
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GKI6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948388   ⟸   XM_039092460
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GKI6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000043336   ⟸   ENSRNOT00000045085
RefSeq Acc Id: ENSRNOP00000093961   ⟸   ENSRNOT00000115443
RefSeq Acc Id: NP_001406289   ⟸   NM_001419360
- Peptide Label: isoform 2 precursor
RefSeq Acc Id: NP_001406288   ⟸   NM_001419359
- Peptide Label: isoform 1 precursor
RefSeq Acc Id: XP_063129704   ⟸   XM_063273634
- Peptide Label: isoform X1
Protein Domains
G-protein coupled receptors family 3 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LPZ0-F1-model_v2 AlphaFold F1LPZ0 1-851 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1597426 AgrOrtholog
BioCyc Gene G2FUF-16698 BioCyc
Ensembl Genes ENSRNOG00000042719 Ensembl
  ENSRNOG00000046835 Ensembl
  ENSRNOG00000063032 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000115443 ENTREZGENE
  ENSRNOT00000115443.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
KEGG Report rno:689060 UniProtKB/TrEMBL
NCBI Gene 689060 ENTREZGENE
PANTHER PTHR24061 UniProtKB/TrEMBL
  VOMERONASAL 2, RECEPTOR 10-RELATED UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vom2r71 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000042719 RatGTEx
  ENSRNOG00000046835 RatGTEx
  ENSRNOG00000063032 RatGTEx
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A0A8I6GKI6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Vom2r71  vomeronasal 2 receptor, 71  LOC100911147  vomeronasal type-2 receptor 26-like  Data merged from RGD:6494652 737654 PROVISIONAL
2012-07-05 LOC100911147  vomeronasal type-2 receptor 26-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-07-23 Vom2r71  vomeronasal 2 receptor, 71    vomeronasal 2, receptor 71  Symbol and Name updated 1299863 APPROVED
2008-05-29 Vom2r71  vomeronasal 2, receptor 71  LOC689060  similar to vomeronasal 2, receptor, 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC689060  similar to vomeronasal 2, receptor, 1  LOC681762  similar to vomeronasal 2, receptor, 9  Data merged from RGD:1591642 1643240 APPROVED
2006-11-20 LOC689060  similar to vomeronasal 2, receptor, 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC681762  similar to vomeronasal 2, receptor, 9      Symbol and Name status set to provisional 70820 PROVISIONAL