Ube2r2l2 (ubiquitin-conjugating enzyme E2R 2 like 2) - Rat Genome Database

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Gene: Ube2r2l2 (ubiquitin-conjugating enzyme E2R 2 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ube2r2l2 (Ensembl: LOC691764)
Name: ubiquitin-conjugating enzyme E2R 2 like 2 (Ensembl:similar to ubiquitin-conjugating enzyme E2R 2)
RGD ID: 1595959
Description: Predicted to enable ATP binding activity and transferase activity.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC691708; LOC691764; similar to ubiquitin-conjugating enzyme E2R 2; Ube2r2l1; ubiquitin-conjugating enzyme E2 R2-like; ubiquitin-conjugating enzyme E2R 2 like 1
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8718,624,095 - 18,659,956 (+)NCBIGRCr8
mRatBN7.2717,045,737 - 17,118,072 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl717,057,079 - 17,117,685 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0721,152,885 - 21,180,063 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0721,319,800 - 21,343,695 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4719,105,932 - 19,191,905 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Ube2r2l2
681 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat

Markers in Region
D14Mit14  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,116,236 - 17,116,475 (+)MAPPERmRatBN7.2
mRatBN7.2716,022,133 - 16,022,370 (+)MAPPERmRatBN7.2
Rnor_6.0721,182,633 - 21,182,864NCBIRnor6.0
Rnor_6.0721,180,182 - 21,180,417NCBIRnor6.0
Rnor_5.0721,343,813 - 21,344,048UniSTSRnor5.0
Rnor_5.0721,346,797 - 21,347,028UniSTSRnor5.0
RGSC_v3.4719,190,401 - 19,190,632UniSTSRGSC3.4
RGSC_v3.4718,638,086 - 18,638,322UniSTSRGSC3.4
RGSC_v3.1719,198,536 - 19,198,882RGD
Cytogenetic Map7q13UniSTS
AU047534  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,116,236 - 17,116,472 (+)MAPPERmRatBN7.2
mRatBN7.2716,022,133 - 16,022,367 (+)MAPPERmRatBN7.2
Rnor_6.0721,180,182 - 21,180,414NCBIRnor6.0
Rnor_6.0721,182,633 - 21,182,861NCBIRnor6.0
Rnor_5.0721,346,797 - 21,347,025UniSTSRnor5.0
Rnor_5.0721,343,813 - 21,344,045UniSTSRnor5.0
RGSC_v3.4719,190,401 - 19,190,629UniSTSRGSC3.4
RGSC_v3.4718,638,086 - 18,638,319UniSTSRGSC3.4
Cytogenetic Map7q13UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000098371   ⟹   ENSRNOP00000095042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl717,057,079 - 17,117,685 (+)Ensembl
RefSeq Acc Id: XM_039080495   ⟹   XP_038936423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8718,624,095 - 18,659,956 (+)NCBI
mRatBN7.2717,090,236 - 17,118,072 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038936423 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000095042.1
Reference Protein Sequences
RefSeq Acc Id: XP_038936423   ⟸   XM_039080495
- UniProtKB: A0A8I6AKR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000095042   ⟸   ENSRNOT00000098371
Protein Domains
UBC core

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-34653 BioCyc
Ensembl Genes ENSRNOG00000065932 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000098371.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/TrEMBL
InterPro UBQ-conjugat_E2 UniProtKB/TrEMBL
  UBQ-conjugating_AS UniProtKB/TrEMBL
  UBQ-conjugating_enzyme/RWD UniProtKB/TrEMBL
NCBI Gene 691764 ENTREZGENE
PANTHER UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/TrEMBL
  UBIQUITIN-CONJUGATING ENZYME E2 R2 UniProtKB/TrEMBL
Pfam UQ_con UniProtKB/TrEMBL
PhenoGen Ube2r2l2 PhenoGen
PROSITE UBC_1 UniProtKB/TrEMBL
  UBC_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000065932 RatGTEx
RNAcentral URS0000CCFF39 RNACentral
  URS0000CD063C RNACentral
Superfamily-SCOP SSF54495 UniProtKB/TrEMBL
UniProt A0A8I6AKR3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-17 Ube2r2l2  ubiquitin-conjugating enzyme E2R 2 like 2  Ube2r2l1  ubiquitin-conjugating enzyme E2R 2 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Ube2r2l1  ubiquitin-conjugating enzyme E2R 2 like 1  LOC691764  similar to ubiquitin-conjugating enzyme E2R 2  Symbol and Name Changed 1299863 APPROVED
2015-07-29 LOC691764  similar to ubiquitin-conjugating enzyme E2R 2  LOC691708  similar to ubiquitin-conjugating enzyme E2R 2  Data merged from RGD:1596006 737654 PROVISIONAL
2006-11-20 LOC691708  similar to ubiquitin-conjugating enzyme E2R 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC691764  similar to ubiquitin-conjugating enzyme E2R 2      Symbol and Name status set to provisional 70820 PROVISIONAL