Sinhcaf (SIN3-HDAC complex associated factor)

Gene: Sinhcaf (SIN3-HDAC complex associated factor) Rattus norvegicus

Analyze

Symbol:

Sinhcaf

Name:

SIN3-HDAC complex associated factor

RGD ID:

1595037

Description:

Predicted to be involved in negative regulation of cell differentiation; negative regulation of cell migration; and positive regulation of cell population proliferation. Predicted to be part of Sin3-type complex. Orthologous to human SINHCAF (SIN3-HDAC complex associated factor); INTERACTS WITH 17beta-estradiol; 2,3,4,7,8-Pentachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Fam60a; family with sequence similarity 60, member A; LOC100909791; LOC686611; MGC187734; protein FAM60A-like; similar to Protein FAM60A (Tera protein); SIN3-HDAC complex-associated factor

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SINHCAF (SIN3-HDAC complex associated factor)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Sinhcaf (SIN3-HDAC complex associated factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sinhcaf (SIN3-HDAC complex associated factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SINHCAF (SIN3-HDAC complex associated factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SINHCAF (SIN3-HDAC complex associated factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sinhcaf (SIN3-HDAC complex associated factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SINHCAF (SIN3-HDAC complex associated factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SINHCAF (SIN3-HDAC complex associated factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sinhcaf (SIN3-HDAC complex associated factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SINHCAF (SIN3-HDAC complex associated factor)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sinhcaf (SIN3-HDAC complex associated factor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG44774	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	sinhcaf	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sinhcaf	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	183,619,647 - 183,644,628 (-)	NCBI		GRCr8
mRatBN7.2	4	181,888,301 - 181,913,294 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	181,888,312 - 181,910,276 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	188,163,184 - 188,188,284 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	183,947,713 - 183,972,815 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	182,568,207 - 182,593,309 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	183,401,314 - 183,426,439 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	183,401,318 - 183,426,439 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	247,532,024 - 247,556,126 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	4	170,356,442 - 170,381,382 (-)	NCBI		Celera
Cytogenetic Map	4	q44	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

pancreatic cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP,ISO)

2,3,4,7,8-Pentachlorodibenzofuran (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

butan-1-ol (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

choline (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dibutyl phthalate (EXP,ISO)

dorsomorphin (ISO)

doxifluridine (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

folic acid (ISO)

fulvestrant (ISO)

furan (EXP)

hydrogen sulfide (ISO)

L-methionine (ISO)

lead(0) (ISO)

leflunomide (ISO)

manganese(II) chloride (EXP)

menadione (ISO)

orphenadrine (EXP)

paracetamol (EXP,ISO)

phenylmercury acetate (ISO)

piroxicam (ISO)

rac-lactic acid (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

torcetrapib (ISO)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of cell differentiation (ISO)

negative regulation of cell migration (IBA,ISO)

positive regulation of cell population proliferation (ISO)

Cellular Component

Sin3-type complex (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:22984288	PMID:28554894

Genomics

Comparative Map Data

Sinhcaf
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	183,619,647 - 183,644,628 (-)	NCBI		GRCr8
mRatBN7.2	4	181,888,301 - 181,913,294 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	181,888,312 - 181,910,276 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	188,163,184 - 188,188,284 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	183,947,713 - 183,972,815 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	182,568,207 - 182,593,309 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	183,401,314 - 183,426,439 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	183,401,318 - 183,426,439 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	247,532,024 - 247,556,126 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	4	170,356,442 - 170,381,382 (-)	NCBI		Celera
Cytogenetic Map	4	q44	NCBI

SINHCAF
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	31,280,584 - 31,326,150 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	31,280,584 - 31,327,058 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	31,433,518 - 31,479,084 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	31,324,785 - 31,370,340 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	31,324,784 - 31,370,340	NCBI
Celera	12	11,254,383 - 11,300,023 (-)	NCBI		Celera
Cytogenetic Map	12	p11.21	NCBI
HuRef	12	31,186,852 - 31,232,433 (-)	NCBI		HuRef
CHM1_1	12	31,398,520 - 31,444,157 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	31,157,116 - 31,202,680 (-)	NCBI		T2T-CHM13v2.0

Sinhcaf
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	148,822,538 - 148,847,968 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	148,822,533 - 148,847,965 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	148,921,057 - 148,946,470 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	148,921,035 - 148,946,467 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	148,869,579 - 148,894,954 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	148,878,227 - 148,903,602 (-)	NCBI		MGSCv36	mm8
Celera	6	151,959,092 - 151,984,485 (-)	NCBI		Celera
Cytogenetic Map	6	G3	NCBI
cM Map	6	78.67	NCBI

Sinhcaf
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955505	4,365,386 - 4,379,232 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955505	4,344,465 - 4,377,463 (+)	NCBI	ChiLan1.0	ChiLan1.0

SINHCAF
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	65,447,437 - 65,492,192 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	65,442,956 - 65,487,773 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	54,914,625 - 54,960,258 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	57,498,428 - 57,544,498 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	57,498,428 - 57,544,489 (+)	Ensembl	panpan1.1		panPan2

SINHCAF
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	17,421,065 - 17,456,628 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	17,429,052 - 17,455,144 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	28,961,376 - 28,996,459 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	17,604,428 - 17,639,788 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	17,604,757 - 17,639,726 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	17,413,787 - 17,449,047 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	17,444,696 - 17,480,029 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	29,114,405 - 29,149,788 (-)	NCBI		UU_Cfam_GSD_1.0

Sinhcaf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	78,020,954 - 78,055,473 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936607	4,854,332 - 4,889,999 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SINHCAF
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	42,930,521 - 42,985,144 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	42,930,445 - 42,963,604 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SINHCAF
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	30,755,143 - 30,797,383 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666069	4,184,169 - 4,230,836 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sinhcaf
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624778	4,917,195 - 4,947,871 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624778	4,917,169 - 4,947,880 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Sinhcaf
88 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	81
Count of miRNA genes:	71
Interacting mature miRNAs:	76
Transcripts:	ENSRNOT00000071930
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
6478718	Anxrr34	Anxiety related response QTL 34		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
6478748	Anxrr42	Anxiety related response QTL 42		0.28008	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
6478754	Anxrr43	Anxiety related response QTL 43		0.14035	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	144639524	182687754	Rat
6478693	Anxrr32	Anxiety related response QTL 32		0.00092	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	144639524	182687754	Rat
6478700	Anxrr33	Anxiety related response QTL 33		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
10401796	Kidm48	Kidney mass QTL 48			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	145568712	182687754	Rat
10053718	Scort25	Serum corticosterone level QTL 25	2.15	0.0097	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	155561574	182687754	Rat
1300109	Rf13	Renal function QTL 13	3.91		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	4	157710145	182687754	Rat

Markers in Region

D4Rat207

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	181,900,635 - 181,900,813 (+)	MAPPER	mRatBN7.2
mRatBN7.2	4	181,900,635 - 181,900,813 (-)	MAPPER	mRatBN7.2
Rnor_6.0	16	18,445,430 - 18,445,607	NCBI	Rnor6.0
Rnor_6.0	4	183,414,218 - 183,414,395	NCBI	Rnor6.0
Rnor_5.0	16	18,323,079 - 18,323,256	UniSTS	Rnor5.0
Rnor_5.0	4	247,544,444 - 247,544,621	UniSTS	Rnor5.0
Celera	4	170,368,814 - 170,368,991	UniSTS
RH 3.4 Map	4	1118.2	RGD
RH 3.4 Map	4	1118.2	UniSTS
RH 2.0 Map	4	1151.5	RGD
SHRSP x BN Map	4	98.8499	RGD

BI282073

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	4	183,424,351 - 183,424,561	NCBI	Rnor6.0
Celera	4	170,381,181 - 170,381,385	UniSTS
RH 3.4 Map	4	1130.44	UniSTS

Fam60a

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	181,888,596 - 181,889,508 (-)	MAPPER	mRatBN7.2
Rnor_6.0	4	183,401,605 - 183,403,086	NCBI	Rnor6.0
Rnor_6.0	16	18,456,752 - 18,457,659	NCBI	Rnor6.0
Rnor_5.0	16	18,334,401 - 18,335,308	UniSTS	Rnor5.0
Rnor_5.0	4	247,532,315 - 247,533,312	UniSTS	Rnor5.0
Celera	4	170,356,733 - 170,357,644	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	20	21	12	18	12			45	22	39	11
Low		23	36	29	1	29	8	10	29	13	2		8
Below cutoff								1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001134711	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001134712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286697	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EV762285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000071930 ⟹ ENSRNOP00000067114

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	181,888,312 - 181,910,276 (-)	Ensembl
Rnor_6.0 Ensembl	4	183,403,000 - 183,424,449 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000083310 ⟹ ENSRNOP00000071885

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	4	183,401,318 - 183,426,439 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089160 ⟹ ENSRNOP00000072156

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	4	183,401,318 - 183,417,667 (-)	Ensembl

RefSeq Acc Id:

NM_001134711 ⟹ NP_001128183

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	183,619,652 - 183,641,626 (-)	NCBI
mRatBN7.2	4	181,888,306 - 181,910,276 (-)	NCBI
Rnor_6.0	4	183,401,314 - 183,417,665 (-)	NCBI
Rnor_5.0	4	247,532,024 - 247,556,126 (-)	NCBI
Celera	4	170,356,442 - 170,378,392 (-)	NCBI

Sequence:

show sequence

GATTCTGTTATAATCAAATGATGTTTGTAAGAGAGACTTGAATGACTTAAGAGAAAAGGGAAAG
CAAGGTCTTCACCTTCTGTTATTTTGTGGGTGGTTGGAGATTTTAAAGAACATCTGTGTATGTG
TATCTTCATATATGAGACCATATATTGGGGGAGTTGGATCTCACAACCACAGGAATTAAGGGAT
CAAATTCAGCTGCGTCCTTAGTGCCTTGTAAAGCTGTCCTCACTCTCTGTTCTGTAATATCTGC
AGTGGAGTGGATTGTCTAACAGCTTTGAACCAGAAGAAAAGATGTTTGGTTTTCACAAGCCAAA
GATGTACCGAAGTATAGAAGGCTGCTGTATCTGCAGAGCCAAGTCCTCCAGCTCTCGGTTCACG
GACAGCAAGCGCTATGAGAAGGACTTCCAGAGCTGCTTTGGGCTGCATGAGACTCGCTCAGGAG
ACATCTGCAACGCCTGTGTGCTGCTTGTGAAAAGATGGAAGAAGCTGCCGGCAGGATCCAAAAA
AAACTGGAATCACGTCGTAGATGCAAGAGCAGGCCCCAGTCTAAAGACAACACTGAAACCAAAG
AAAGTGAAGACTCTGTCTGGAAACAGGATGAAAAGCAGCCAGATCAGTAAGCTGCAGAAGGAGT
TTAAACGCCACAATTCTGATGCTCATAGCACCACCTCAAGTGCCTCTCCAGCCCAGTCTCCATG
CTATAGTAACCAGTCAGACGAGGGCTCAGATACAGAGATGGCTTCCAGCTCTAATAGAACTCCG
GTTTTTTCCTTCTTAGATCTTACCTACTGGAAAAGACAGAAAATATGTTGTGGGATCATCTATA
AGGGCCGTTTTGGGGAAGTCCTCATCGACACTCATCTCTTCAAGCCTTGCTGCAGCAGTAAGAA
AGCTGCTGCCGAGAAGCCAGAGGAGCAGGCCCCAGCGCCTCTGCCCATCTCCACTCAGGAGTGG
TGACTGAGGTTCATTTAGAAGGGAGCGAAGAACGATTTAAACTTTGAAAAGACCACAAAACAAA
CTGACCCTCCTATTTTTAACTTGGATACCTGCTATTCTGCCAAAAGACATTTTCTAGAATAGTT
TTTAATGGGTTACTATCCTTACCCTTCACCCAACCAACTCTGAAGCCAGTCTCTAGCTTACTGC
AAGAAAAGACGTGTACATACTATTTAAGATGCTGAGTATCTCATAGGAAAGCTGAATGCTGCTG
TAAAGTGCTCTTTAAGTCTTTTAAAATCCCCTCTAATGAATGGAATAGGGGAACTTCAGGGGAC
AGAGATGGGATTTGTTGTGTGATAAACCATATGTAGTTTAGTCTTTCTGTGGAGAGGCAGTGGT
TGGGGCATTTTTAAATGGCTGGCTACACTTCTTTTCCCTCATGATAATTTGTCATAACTCAGTA
GCATGACCTGTCCCTAGAAGGTAGTTAAAATTTTTTACATGCTAAGGCGTTGCCAAGGTTCTGA
TGATTCAGACCTGTACTACTGATTATTAAGCAGGACAGACTGAGCTTTCTGCAAATAGCTTGAA
GGAGGAAGCAATTTCTGAGCACACAAGTAGCACCGTGTCGCCTCCCCTTATCTTCACATTGATA
AAAGACTTTATGTGGATCTCGTAAAACAGAACCAGATCTCCTTCTGGGGAAGGCCTGCCTCTAG
GATGGGCAAGGTCCTGTAGGGATAGAACCAAAGCATCACCACAAAGTAGAGAACACATGTGGTT
AGAAACTACTTAATCAGAATGGCTAAGTCCTGGGGACGCATGGACACAGTTGTTGATGCTGCTT
GGGGCGTGTCTCCTAGAGGGCTCACAGTATGTAAATAATTGACATTGGTGTTAACACGACTGTC
TGGGATTCACTGAAATCCACATGATTCAGTTCTAGCTCTGGATTACCTCAGTTGACCTTTGTGG
AGGTTTTATCTGTAGAGTAGCTCTTTGCCTTGTCATAAACCTTATTAGGGTTTGGGGTTCTGTT
GTTTTGTTGTTTCTCTCCCACTATTTAAAGCTGACTAGAAGGGTTAGTTGTGTGTTGAGGCTAA
GTTGGGTGGTTGGGTCGGCTTCTTAACATTAAGATAGCTGAGTGGAGCTCCACACCTGGATCTC
AATGACTCGGTTGGCTTCTCAGTGGAACCCAACTGAGGTTGTCTAATCGCCTCTTCTCAAAAGT
TCAGGAAAAAGAGTAGTGCCACGTGAGACCTCACAGAGGAGGTGTACGTGGCTGCCTTAGTATT
CTGTTGCTCATGATTATTTTAGAAACTGGATTTTTAAAGACTTTTAGAGTTTCATAACAAGGAA
AAGCCACAGTTTGTGTCATCCTACAGTTTTACATCGTGTATTTCTTCCTTTTAGAAAAAACCTA
CCTAGTACAAGGTACCACATGCACAGACTGCCCAGTGAATGGGTCAATTCTCCACAGCCCTGGT
GTAGTGCAGAGTCCAGTCATTACCATTCTCCTGCGTTACTTTGACATGGGATTTTTTTTTTTTT
TTGTACATTTTGGCTGCAGTATTGGTGGTAGAATATACTTTGATGGATCATCTCTACTTCTGTA
TTTATTTATTTATTACTAGACCTCAACCACAGCCTTCTCCCCCTCCACTCTCTGCCTGTAGGAT
GTACTGTATGTAGTCATGCACTTTGTATTAATATATTAGAAATCTACAGATCTGTTTTGTACTT
TTTATACTGTTGGATACTTATAATCAAAACTTTACTCTAGGGTATTGAATAAATTTAGTCTTAT
TAGAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001134712 ⟹ NP_001128184

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	183,619,652 - 183,644,628 (-)	NCBI
mRatBN7.2	4	181,888,306 - 181,913,278 (-)	NCBI
Rnor_6.0	4	183,401,314 - 183,426,439 (-)	NCBI
Rnor_5.0	4	247,532,024 - 247,556,126 (-)	NCBI
Celera	4	170,356,442 - 170,381,382 (-)	RGD

Sequence:

show sequence

CAACTGAAGAACTGCTGGAGACAATCTTTCTGGACTCGGCGCTGGCGGAGGGAGTGCTTGCAGG
GGGTTGGCCTGGTGCAGTTTGCACCGTGGGGACGCTGCTGCGCGTGGAAGCTTTGAACCAGAAG
AAAAGATGTTTGGTTTTCACAAGCCAAAGATGTACCGAAGTATAGAAGGCTGCTGTATCTGCAG
AGCCAAGTCCTCCAGCTCTCGGTTCACGGACAGCAAGCGCTATGAGAAGGACTTCCAGAGCTGC
TTTGGGCTGCATGAGACTCGCTCAGGAGACATCTGCAACGCCTGTGTGCTGCTTGTGAAAAGAT
GGAAGAAGCTGCCGGCAGGATCCAAAAAAAACTGGAATCACGTCGTAGATGCAAGAGCAGGCCC
CAGTCTAAAGACAACACTGAAACCAAAGAAAGTGAAGACTCTGTCTGGAAACAGGATGAAAAGC
AGCCAGATCAGTAAGCTGCAGAAGGAGTTTAAACGCCACAATTCTGATGCTCATAGCACCACCT
CAAGTGCCTCTCCAGCCCAGTCTCCATGCTATAGTAACCAGTCAGACGAGGGCTCAGATACAGA
GATGGCTTCCAGCTCTAATAGAACTCCGGTTTTTTCCTTCTTAGATCTTACCTACTGGAAAAGA
CAGAAAATATGTTGTGGGATCATCTATAAGGGCCGTTTTGGGGAAGTCCTCATCGACACTCATC
TCTTCAAGCCTTGCTGCAGCAGTAAGAAAGCTGCTGCCGAGAAGCCAGAGGAGCAGGCCCCAGC
GCCTCTGCCCATCTCCACTCAGGAGTGGTGACTGAGGTTCATTTAGAAGGGAGCGAAGAACGAT
TTAAACTTTGAAAAGACCACAAAACAAACTGACCCTCCTATTTTTAACTTGGATACCTGCTATT
CTGCCAAAAGACATTTTCTAGAATAGTTTTTAATGGGTTACTATCCTTACCCTTCACCCAACCA
ACTCTGAAGCCAGTCTCTAGCTTACTGCAAGAAAAGACGTGTACATACTATTTAAGATGCTGAG
TATCTCATAGGAAAGCTGAATGCTGCTGTAAAGTGCTCTTTAAGTCTTTTAAAATCCCCTCTAA
TGAATGGAATAGGGGAACTTCAGGGGACAGAGATGGGATTTGTTGTGTGATAAACCATATGTAG
TTTAGTCTTTCTGTGGAGAGGCAGTGGTTGGGGCATTTTTAAATGGCTGGCTACACTTCTTTTC
CCTCATGATAATTTGTCATAACTCAGTAGCATGACCTGTCCCTAGAAGGTAGTTAAAATTTTTT
ACATGCTAAGGCGTTGCCAAGGTTCTGATGATTCAGACCTGTACTACTGATTATTAAGCAGGAC
AGACTGAGCTTTCTGCAAATAGCTTGAAGGAGGAAGCAATTTCTGAGCACACAAGTAGCACCGT
GTCGCCTCCCCTTATCTTCACATTGATAAAAGACTTTATGTGGATCTCGTAAAACAGAACCAGA
TCTCCTTCTGGGGAAGGCCTGCCTCTAGGATGGGCAAGGTCCTGTAGGGATAGAACCAAAGCAT
CACCACAAAGTAGAGAACACATGTGGTTAGAAACTACTTAATCAGAATGGCTAAGTCCTGGGGA
CGCATGGACACAGTTGTTGATGCTGCTTGGGGCGTGTCTCCTAGAGGGCTCACAGTATGTAAAT
AATTGACATTGGTGTTAACACGACTGTCTGGGATTCACTGAAATCCACATGATTCAGTTCTAGC
TCTGGATTACCTCAGTTGACCTTTGTGGAGGTTTTATCTGTAGAGTAGCTCTTTGCCTTGTCAT
AAACCTTATTAGGGTTTGGGGTTCTGTTGTTTTGTTGTTTCTCTCCCACTATTTAAAGCTGACT
AGAAGGGTTAGTTGTGTGTTGAGGCTAAGTTGGGTGGTTGGGTCGGCTTCTTAACATTAAGATA
GCTGAGTGGAGCTCCACACCTGGATCTCAATGACTCGGTTGGCTTCTCAGTGGAACCCAACTGA
GGTTGTCTAATCGCCTCTTCTCAAAAGTTCAGGAAAAAGAGTAGTGCCACGTGAGACCTCACAG
AGGAGGTGTACGTGGCTGCCTTAGTATTCTGTTGCTCATGATTATTTTAGAAACTGGATTTTTA
AAGACTTTTAGAGTTTCATAACAAGGAAAAGCCACAGTTTGTGTCATCCTACAGTTTTACATCG
TGTATTTCTTCCTTTTAGAAAAAACCTACCTAGTACAAGGTACCACATGCACAGACTGCCCAGT
GAATGGGTCAATTCTCCACAGCCCTGGTGTAGTGCAGAGTCCAGTCATTACCATTCTCCTGCGT
TACTTTGACATGGGATTTTTTTTTTTTTTTGTACATTTTGGCTGCAGTATTGGTGGTAGAATAT
ACTTTGATGGATCATCTCTACTTCTGTATTTATTTATTTATTACTAGACCTCAACCACAGCCTT
CTCCCCCTCCACTCTCTGCCTGTAGGATGTACTGTATGTAGTCATGCACTTTGTATTAATATAT
TAGAAATCTACAGATCTGTTTTGTACTTTTTATACTGTTGGATACTTATAATCAAAACTTTACT
CTAGGGTATTGAATAAATTTAGTCTTATTAGAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039108360 ⟹ XP_038964288

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	183,619,647 - 183,644,397 (-)	NCBI
mRatBN7.2	4	181,888,301 - 181,913,055 (-)	NCBI

RefSeq Acc Id:

XM_039108361 ⟹ XP_038964289

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	183,619,647 - 183,643,131 (-)	NCBI
mRatBN7.2	4	181,888,301 - 181,911,781 (-)	NCBI

RefSeq Acc Id:

XM_063286697 ⟹ XP_063142767

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	183,619,647 - 183,643,721 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001128183	(Get FASTA)	NCBI Sequence Viewer
	NP_001128184	(Get FASTA)	NCBI Sequence Viewer
	XP_038964288	(Get FASTA)	NCBI Sequence Viewer
	XP_038964289	(Get FASTA)	NCBI Sequence Viewer
	XP_063142767	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68169	(Get FASTA)	NCBI Sequence Viewer
	EDM01372	(Get FASTA)	NCBI Sequence Viewer
	EDM01373	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000067114
	ENSRNOP00000067114.3

RefSeq Acc Id:

NP_001128184 ⟸ NM_001134712

- UniProtKB:

B4F781 (UniProtKB/TrEMBL), M0RC11 (UniProtKB/TrEMBL), A0A9K3Y7U5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWK
KLPAGSKKNWNHVVDARAGPSLKTTLKPKKVKTLSGNRMKSSQISKLQKEFKRHNSDAHSTTSS
ASPAQSPCYSNQSDEGSDTEMASSSNRTPVFSFLDLTYWKRQKICCGIIYKGRFGEVLIDTHLF
KPCCSSKKAAAEKPEEQAPAPLPISTQEW

hide sequence

RefSeq Acc Id:

NP_001128183 ⟸ NM_001134711

- UniProtKB:

B4F781 (UniProtKB/TrEMBL), M0RC11 (UniProtKB/TrEMBL), A0A9K3Y7U5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWK
KLPAGSKKNWNHVVDARAGPSLKTTLKPKKVKTLSGNRMKSSQISKLQKEFKRHNSDAHSTTSS
ASPAQSPCYSNQSDEGSDTEMASSSNRTPVFSFLDLTYWKRQKICCGIIYKGRFGEVLIDTHLF
KPCCSSKKAAAEKPEEQAPAPLPISTQEW

hide sequence

RefSeq Acc Id:

ENSRNOP00000072156 ⟸ ENSRNOT00000089160

RefSeq Acc Id:

ENSRNOP00000071885 ⟸ ENSRNOT00000083310

RefSeq Acc Id:

ENSRNOP00000067114 ⟸ ENSRNOT00000071930

RefSeq Acc Id:	XP_038964288 ⟸ XM_039108360
- Peptide Label:	isoform X1
- UniProtKB:	M0RC11 (UniProtKB/TrEMBL), A0A9K3Y7U5 (UniProtKB/TrEMBL), B4F781 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038964289 ⟸ XM_039108361
- Peptide Label:	isoform X1
- UniProtKB:	M0RC11 (UniProtKB/TrEMBL), A0A9K3Y7U5 (UniProtKB/TrEMBL), B4F781 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142767 ⟸ XM_063286697
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0RC11-F1-model_v2	AlphaFold	M0RC11	1-261	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693514

Promoter ID:

EPDNEW_R4039

Type:

initiation region

Name:

Sinhcaf_1

Description:

SIN3-HDAC complex associated factor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	183,426,455 - 183,426,515	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1595037	AgrOrtholog
BioCyc Gene	G2FUF-42371	BioCyc
Ensembl Genes	ENSRNOG00000049943	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000071930	ENTREZGENE
	ENSRNOT00000071930.3	UniProtKB/TrEMBL
InterPro	FAM60A	UniProtKB/TrEMBL
KEGG Report	rno:686611	UniProtKB/TrEMBL
NCBI Gene	686611	ENTREZGENE
PANTHER	PTHR13422	UniProtKB/TrEMBL
	SIN3-HDAC COMPLEX-ASSOCIATED FACTOR	UniProtKB/TrEMBL
Pfam	FAM60A	UniProtKB/TrEMBL
PhenoGen	Sinhcaf	PhenoGen
RatGTEx	ENSRNOG00000049943	RatGTEx
UniProt	A0A9K3Y7U5	ENTREZGENE, UniProtKB/TrEMBL
	B4F781	ENTREZGENE, UniProtKB/TrEMBL
	M0RC11	ENTREZGENE
UniProt Secondary	M0RC11	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Sinhcaf	SIN3-HDAC complex associated factor	LOC100909791	protein FAM60A-like	Data merged from RGD:6501581	737654	PROVISIONAL
2017-07-31	Sinhcaf	SIN3-HDAC complex associated factor	Fam60a	family with sequence similarity 60, member A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-05	LOC100909791	protein FAM60A-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-10-08	Fam60a	family with sequence similarity 60, member A	LOC686611	similar to Protein FAM60A (Tera protein)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC686611	similar to Protein FAM60A (Tera protein)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD