Saa3 (serum amyloid A 3) - Rat Genome Database

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Gene: Saa3 (serum amyloid A 3) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Saa3
Name: serum amyloid A 3
RGD ID: 1594860
Description: Orthologous to human SAAL1 (serum amyloid A like 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC687992; Saal1; serum amyloid A-like 1; similar to Serum amyloid A-3 protein precursor; uncharacterized protein LOC687992
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81106,354,986 - 106,358,432 (-)NCBIGRCr8
mRatBN7.2197,218,706 - 97,222,150 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1102,604,798 - 102,608,267 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01111,076,788 - 111,080,254 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01104,367,068 - 104,370,512 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01102,738,691 - 102,743,571 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01103,813,349 - 103,818,197 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera191,465,623 - 91,470,503 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Saa3
20 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:113
Count of miRNA genes:91
Interacting mature miRNAs:95
Transcripts:ENSRNOT00000016254
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)194494440117601394Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat

Markers in Region
RH137346  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2197,218,726 - 97,218,932 (+)MAPPERmRatBN7.2
Rnor_6.01102,738,712 - 102,738,917NCBIRnor6.0
Rnor_5.01103,813,370 - 103,813,575UniSTSRnor5.0
RGSC_v3.4197,248,463 - 97,248,668UniSTSRGSC3.4
Celera191,465,644 - 91,465,849UniSTS
RH 3.4 Map19269.4UniSTS
Cytogenetic Map1q22UniSTS
RH140916  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2197,200,158 - 97,200,696 (+)MAPPERmRatBN7.2
Rnor_6.01102,720,146 - 102,720,683NCBIRnor6.0
Rnor_5.01103,794,804 - 103,795,341UniSTSRnor5.0
RGSC_v3.4197,229,896 - 97,230,433UniSTSRGSC3.4
Celera191,447,077 - 91,447,614UniSTS
RH 3.4 Map1908.5UniSTS
Cytogenetic Map1q22UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_001402101   ⟹   NP_001389030
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81106,354,986 - 106,358,430 (-)NCBI
mRatBN7.2197,218,706 - 97,222,150 (-)NCBI
RefSeq Acc Id: XM_063274266   ⟹   XP_063130336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81106,354,986 - 106,358,432 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001389030 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130336 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM07258 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001389030   ⟸   NM_001402101
- Peptide Label: precursor
- UniProtKB: A6JBC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130336   ⟸   XM_063274266
- Peptide Label: isoform X1
- UniProtKB: A6JBC6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1594860 AgrOrtholog
BioCyc Gene G2FUF-59618 BioCyc
Gene3D-CATH Serum amyloid A protein UniProtKB/TrEMBL
InterPro Serum_amyloid_A UniProtKB/TrEMBL
NCBI Gene 687992 ENTREZGENE
Pfam SAA UniProtKB/TrEMBL
PhenoGen Saa3 PhenoGen
PIRSF Serum_amyloid_A UniProtKB/TrEMBL
PRINTS SERUMAMYLOID UniProtKB/TrEMBL
PROSITE SAA UniProtKB/TrEMBL
SMART SAA UniProtKB/TrEMBL
UniProt A6JBC5_RAT UniProtKB/TrEMBL
  A6JBC6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-03-04 Saa3  serum amyloid A 3  Saal1  serum amyloid A-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-16 Saal1  serum amyloid A-like 1  LOC687992  similar to Serum amyloid A-3 protein precursor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC687992  similar to Serum amyloid A-3 protein precursor      Symbol and Name status set to provisional 70820 PROVISIONAL