Mageb11 (MAGE family member B11) - Rat Genome Database

Name: Mageb11
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Mageb11 (MAGE family member B11) Rattus norvegicus

Analyze

Symbol:

Mageb11

Name:

MAGE family member B11

RGD ID:

1594017

Description:

INVOLVED IN negative regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC682831; melanoma-associated antigen B5; similar to melanoma antigen family B, 3

RGD Orthologs

Mouse

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	60,141,969 - 60,154,123 (+)	NCBI		GRCr8
mRatBN7.2	X	56,177,647 - 56,178,657 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	56,177,665 - 56,178,657 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	X	60,551,229 - 60,552,367 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	60,551,201 - 60,552,242 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	61,146,995 - 61,148,087 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	X	56,670,083 - 56,671,221 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of transcription by RNA polymerase II (IEA)

Cellular Component

nucleus (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Mageb11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	60,141,969 - 60,154,123 (+)	NCBI		GRCr8
mRatBN7.2	X	56,177,647 - 56,178,657 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	56,177,665 - 56,178,657 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	X	60,551,229 - 60,552,367 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	60,551,201 - 60,552,242 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	61,146,995 - 61,148,087 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	X	56,670,083 - 56,671,221 (+)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

Mageb11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	89,921,961 - 89,936,740 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	89,935,748 - 89,936,740 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	90,878,355 - 90,893,134 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	90,892,142 - 90,893,134 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	88,137,481 - 88,138,473 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	87,144,861 - 87,145,853 (+)	NCBI		MGSCv36	mm8
Celera	X	58,531,392 - 58,532,384 (+)	NCBI		Celera
Cytogenetic Map	X	C1	NCBI
cM Map	X	40.19	NCBI

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	13
Count of miRNA genes:	13
Interacting mature miRNAs:	13
Transcripts:	ENSRNOT00000071500
Prediction methods:	Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
71116	Niddm16	Non-insulin dependent diabetes mellitus QTL 16	7.81		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	15297802	60297802	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	41304447	112935181	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	reproductive system
High
Medium	1
Low	9
Below cutoff	8

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_001063311	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003752058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000071500

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	56,177,665 - 56,178,657 (+)	Ensembl
Rnor_6.0 Ensembl	X	60,551,201 - 60,552,242 (+)	Ensembl

RefSeq Acc Id:

XM_003752058 ⟹ XP_003752106

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	60,141,969 - 60,154,123 (+)	NCBI
mRatBN7.2	X	56,177,647 - 56,178,657 (+)	NCBI
Rnor_6.0	X	60,551,229 - 60,552,367 (+)	NCBI
Rnor_5.0	X	61,146,995 - 61,148,087 (+)	NCBI

Sequence:

show sequence

TGTTATATTAATCAGTCATCATGCCTCGAGGTCAAAAGAGTAAGCTAAATGTTCGAGGGACACA
CCGCCAAGCCATAAATTATGCTCAGGCTTTTGAAGATGCTAAGGAAACAGTAGAGCCAACAGAA
GAGTCTTCTTCTGAATCAGGTGGTACCTTTGAGGTGCCAGAAAAGCAATCAGTGTCCACCATGA
ATATTGATCTCTTTTCTATATTAGATGGCAGTTCTACTGATCTTGATGATGCCGAAAGTCTTTT
TAGGAATTACCACACCATTAATAATCAAGATCTTCTAGCCAGAAAGGTCCTAGTGCTAGTGCAG
ATTCTCCTTAAAAACTACAAAATAAAGCAGCTTACCACAATGGAAGATATGATGCAGGTTATTG
ATAAGGAGGAAATCAATGACTTCCCTGAGATGCTCCGGAAAGCTGCTGAGAGGCTTGCTGATGT
CTTTGCTGTTGAACTGAGGGAAGTTGAATCAAGCCGACGGGTGTATGATCTTATCAGTAAACTG
AAACTACCCAACAATGGGAGGGTTCGTGCTGGCCAGGGCTTTCCAAAGACGGGATTCCTGATGA
CTGTACTGGGCATAATCTTCATGAGTGGCAACTGTGCCCGAGAAGAAGACATCTGGAGAACACT
AAGATATATGGGTGTGTATTCTGGAAAGAAGCACCAAATCTATGGAGAGCCCCGGAAGCTCATC
ACTCAAAATTTTGTGAAGCTAAAGTATTTGGAGTACCGGCAGGTCGCCAACAGTAATCCTCCAC
AATATGAGTTCCTGTGGGGTCCCAAAGCATATGCTGAAACCAACAAGATGACCATCCTAAAGTT
TGTGGCTAAGGTCAATGATATCCCCCCTAGTTGCTTCCCAGATCTTTATGAAGAAGCTTTAAAA
GATGATCAAGGGAAGAATCAAAGCAACCGTAATGTCAGCTCTGCCATTTGTCCCAAAGCTAGGG
CATTTACATTTGTGATGTGTCCAGGGTTTGCTTGCTTCCCTGCCCAAGTTTAAAGGAAAAAGAT
ATAGCAGTAGAAGAAGAATTTCCTTGAAAACATGAAACGAAGCACAGAGAAAACAGGTTAAGGT
AATAAGAGGATAGAAATCAAAACATGAGTAAGCATTGCTTTTTTAGTTGCT

hide sequence

Protein Sequences


Protein RefSeqs	XP_003752106	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL96027	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000083227
	ENSRNOP00000083227.1

RefSeq Acc Id:

XP_003752106 ⟸ XM_003752058

- UniProtKB:

A0A8I5ZVH9 (UniProtKB/TrEMBL), A6IPY6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPRGQKSKLNVRGTHRQAINYAQAFEDAKETVEPTEESSSESGGTFEVPEKQSVSTMNIDLFSI
LDGSSTDLDDAESLFRNYHTINNQDLLARKVLVLVQILLKNYKIKQLTTMEDMMQVIDKEEIND
FPEMLRKAAERLADVFAVELREVESSRRVYDLISKLKLPNNGRVRAGQGFPKTGFLMTVLGIIF
MSGNCAREEDIWRTLRYMGVYSGKKHQIYGEPRKLITQNFVKLKYLEYRQVANSNPPQYEFLWG
PKAYAETNKMTILKFVAKVNDIPPSCFPDLYEEALKDDQGKNQSNRNVSSAICPKARAFTFVMC
PGFACFPAQV

hide sequence

Protein Domains

MAGE

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-2296	BioCyc
Ensembl Genes	ENSRNOG00000050041	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000071500.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.1200	UniProtKB/TrEMBL
	1.10.10.1210	UniProtKB/TrEMBL
InterPro	MAGE	UniProtKB/TrEMBL
	MAGE_WH1	UniProtKB/TrEMBL
	MAGE_WH2	UniProtKB/TrEMBL
	MHD_dom	UniProtKB/TrEMBL
KEGG Report	rno:682831	UniProtKB/TrEMBL
NCBI Gene	682831	ENTREZGENE
PANTHER	MAGE FAMILY MEMBER B11	UniProtKB/TrEMBL
	PTHR11736	UniProtKB/TrEMBL
Pfam	MAGE	UniProtKB/TrEMBL
PhenoGen	Mageb11	PhenoGen
PROSITE	MAGE	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000050041	RatGTEx
SMART	MAGE	UniProtKB/TrEMBL
UniProt	A0A8I5ZVH9	ENTREZGENE, UniProtKB/TrEMBL
	A6IPY6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-09-06	Mageb11	MAGE family member B11	LOC682831	similar to melanoma antigen family B, 3	Name and Symbol changed	629549	APPROVED
2006-11-20	LOC682831	similar to melanoma antigen family B, 3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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