Zfp106 (zinc finger protein 106) - Rat Genome Database

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Gene: Zfp106 (zinc finger protein 106) Rattus norvegicus
Analyze
Symbol: Zfp106
Name: zinc finger protein 106
RGD ID: 1593644
Description: Predicted to enable SH3 domain binding activity and opioid peptide activity. Predicted to act upstream of or within insulin receptor signaling pathway. Predicted to be located in cytosol and membrane. Orthologous to human ZNF106 (zinc finger protein 106); INTERACTS WITH 17beta-estradiol; acrylamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC688018; similar to SH3-domain binding protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83127,912,981 - 127,964,254 (-)NCBIGRCr8
mRatBN7.23107,459,232 - 107,510,507 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,462,096 - 107,510,481 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03112,279,782 - 112,330,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,283,112 - 112,320,762 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,827,186 - 118,857,322 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3106,368,014 - 106,418,966 (-)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,ISO)
membrane  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9507006   PMID:12477932   PMID:22658674  


Genomics

Comparative Map Data
Zfp106
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83127,912,981 - 127,964,254 (-)NCBIGRCr8
mRatBN7.23107,459,232 - 107,510,507 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,462,096 - 107,510,481 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03112,279,782 - 112,330,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,283,112 - 112,320,762 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,827,186 - 118,857,322 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3106,368,014 - 106,418,966 (-)NCBICelera
Cytogenetic Map3q35NCBI
ZNF106
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381542,412,823 - 42,491,141 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1542,412,823 - 42,491,141 (-)EnsemblGRCh38hg38GRCh38
GRCh371542,705,021 - 42,783,339 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361540,492,313 - 40,537,019 (-)NCBINCBI36Build 36hg18NCBI36
Build 341540,492,313 - 40,537,022NCBI
Celera1519,472,730 - 19,517,437 (-)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1519,553,142 - 19,597,638 (-)NCBIHuRef
CHM1_11542,823,506 - 42,868,172 (-)NCBICHM1_1
T2T-CHM13v2.01540,218,871 - 40,297,183 (-)NCBIT2T-CHM13v2.0
Zfp106
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392120,337,303 - 120,394,345 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2120,337,301 - 120,394,324 (-)EnsemblGRCm39 Ensembl
GRCm382120,506,820 - 120,563,864 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2120,506,820 - 120,563,843 (-)EnsemblGRCm38mm10GRCm38
MGSCv372120,332,566 - 120,389,567 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362120,201,054 - 120,255,231 (-)NCBIMGSCv36mm8
Celera2121,660,934 - 121,716,678 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.37NCBI
Znf106
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554169,118,812 - 9,183,583 (-)NCBIChiLan1.0ChiLan1.0
ZNF106
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21631,662,415 - 31,741,644 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11535,815,641 - 35,898,578 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01521,372,911 - 21,452,149 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11539,529,324 - 39,608,427 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1539,533,822 - 39,608,427 (-)Ensemblpanpan1.1panPan2
TMEM87A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1309,215,585 - 9,253,712 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl309,216,702 - 9,253,700 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha309,273,738 - 9,311,932 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0309,350,326 - 9,388,853 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl309,350,330 - 9,388,833 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1309,270,636 - 9,308,807 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0309,375,705 - 9,414,213 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0309,509,957 - 9,548,150 (-)NCBIUU_Cfam_GSD_1.0
Znf106
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864087,864,589 - 87,931,764 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364715,712,655 - 5,779,827 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF106
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1128,893,971 - 128,957,305 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11128,893,965 - 128,957,334 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21143,786,697 - 143,851,832 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF106
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12640,486,801 - 40,567,811 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2640,486,913 - 40,563,332 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048100,446,196 - 100,525,254 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf106
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248049,513,090 - 9,606,758 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zfp106
141 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:144
Count of miRNA genes:113
Interacting mature miRNAs:121
Transcripts:ENSRNOT00000070976, ENSRNOT00000072405
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3102200529115665732Rat

Markers in Region
D3Rat20  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23107,464,053 - 107,464,168 (+)MAPPERmRatBN7.2
Rnor_6.03112,284,604 - 112,284,718NCBIRnor6.0
Rnor_5.03118,832,008 - 118,832,122UniSTSRnor5.0
Celera3106,372,836 - 106,372,950UniSTS
RH 3.4 Map3948.0UniSTS
RH 3.4 Map3948.0RGD
RH 2.0 Map3609.0RGD
SHRSP x BN Map352.9098RGD
RH128384  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23107,459,403 - 107,459,618 (+)MAPPERmRatBN7.2
Rnor_6.03112,279,954 - 112,280,168NCBIRnor6.0
Rnor_5.03118,827,358 - 118,827,572UniSTSRnor5.0
RGSC_v3.43106,999,820 - 107,000,034UniSTSRGSC3.4
Celera3106,368,186 - 106,368,400UniSTS
RH 3.4 Map3938.0UniSTS
RH133910  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23107,475,857 - 107,476,076 (+)MAPPERmRatBN7.2
Rnor_6.03112,296,412 - 112,296,631NCBIRnor6.0
Celera3106,384,640 - 106,384,858UniSTS
RH 3.4 Map3975.5UniSTS
RH137886  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23107,509,502 - 107,509,629 (+)MAPPERmRatBN7.2
Rnor_6.03112,329,302 - 112,329,428NCBIRnor6.0
Rnor_5.03118,876,579 - 118,876,705UniSTSRnor5.0
Celera3106,417,981 - 106,418,107UniSTS
RH 3.4 Map3938.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 50 34 19 34 8 11 74 35 39 11 8
Low 7 7 7 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000078893   ⟹   ENSRNOP00000072228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3107,462,096 - 107,510,481 (-)Ensembl
Rnor_6.0 Ensembl3112,283,112 - 112,320,762 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000081074   ⟹   ENSRNOP00000068586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3107,462,096 - 107,487,979 (-)Ensembl
Rnor_6.0 Ensembl3112,283,112 - 112,320,762 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000089857   ⟹   ENSRNOP00000070083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3112,303,358 - 112,320,762 (-)Ensembl
RefSeq Acc Id: NM_001419871   ⟹   NP_001406800
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83127,912,981 - 127,964,254 (-)NCBI
mRatBN7.23107,459,232 - 107,510,507 (-)NCBI
RefSeq Acc Id: XM_039106519   ⟹   XP_038962447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83127,912,983 - 127,964,249 (-)NCBI
mRatBN7.23107,459,232 - 107,510,493 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001406800 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962447 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66427 (Get FASTA)   NCBI Sequence Viewer  
  AAT77251 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000068586.2
  ENSRNOP00000072228
  ENSRNOP00000072228.2
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000070083   ⟸   ENSRNOT00000089857
RefSeq Acc Id: ENSRNOP00000068586   ⟸   ENSRNOT00000081074
RefSeq Acc Id: ENSRNOP00000072228   ⟸   ENSRNOT00000078893
RefSeq Acc Id: XP_038962447   ⟸   XM_039106519
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001406800   ⟸   NM_001419871
- UniProtKB: A0A0G2K2F8 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JT65-F1-model_v2 AlphaFold A0A0G2JT65 1-1881 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593644 AgrOrtholog
BioCyc Gene G2FUF-48162 BioCyc
Ensembl Genes ENSRNOG00000052583 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078893 ENTREZGENE
  ENSRNOT00000078893.2 UniProtKB/TrEMBL
  ENSRNOT00000081074.2 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro PQQ_beta_propeller_repeat UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
  Znf106 UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene 688018 ENTREZGENE
PANTHER PTHR14435 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 106 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PhenoGen Zfp106 PhenoGen
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000052583 RatGTEx
SMART PQQ UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0G2JT65_RAT UniProtKB/TrEMBL
  A0A0G2K2F8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-10-27 Zfp106  zinc finger protein 106  LOC688018  similar to SH3-domain binding protein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC688018  similar to SH3-domain binding protein 3      Symbol and Name status set to provisional 70820 PROVISIONAL