Ubr2 (ubiquitin protein ligase E3 component n-recognin 2) - Rat Genome Database

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Gene: Ubr2 (ubiquitin protein ligase E3 component n-recognin 2) Rattus norvegicus
Analyze
Symbol: Ubr2
Name: ubiquitin protein ligase E3 component n-recognin 2
RGD ID: 1593237
Description: Predicted to enable histone ubiquitin ligase activity and leucine binding activity. Predicted to be involved in several processes, including cellular response to leucine; meiotic nuclear division; and ubiquitin-dependent protein catabolic process via the N-end rule pathway. Predicted to act upstream of or within male meiosis I; spermatogenesis; and ubiquitin-dependent protein catabolic process. Predicted to be part of chromatin and ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human UBR2 (ubiquitin protein ligase E3 component n-recognin 2); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase UBR2; LOC363188; similar to ubiquitin protein ligase E3 component n-recognin 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,480,058 - 21,559,936 (+)NCBIGRCr8
mRatBN7.2913,982,427 - 14,062,315 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl913,982,329 - 14,062,139 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx922,564,690 - 22,642,065 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,628,725 - 27,706,075 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0925,928,057 - 26,005,432 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,003,058 - 16,080,152 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,003,058 - 16,080,152 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0914,919,790 - 14,997,035 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.499,165,363 - 9,247,261 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera911,731,361 - 11,809,500 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
1H-pyrazole  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
caffeine  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
decabromodiphenyl ether  (EXP)
endosulfan  (ISO)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
fenofibrate  (ISO)
folic acid  (ISO)
glafenine  (EXP)
isoprenaline  (ISO)
L-methionine  (ISO)
methamphetamine  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
pentane-2,3-dione  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phlorizin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tungsten  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11689692   PMID:12477932   PMID:14585983   PMID:19028597   PMID:20080676   PMID:20298436   PMID:28708824   PMID:28806172  


Genomics

Comparative Map Data
Ubr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,480,058 - 21,559,936 (+)NCBIGRCr8
mRatBN7.2913,982,427 - 14,062,315 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl913,982,329 - 14,062,139 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx922,564,690 - 22,642,065 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,628,725 - 27,706,075 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0925,928,057 - 26,005,432 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,003,058 - 16,080,152 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,003,058 - 16,080,152 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0914,919,790 - 14,997,035 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.499,165,363 - 9,247,261 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera911,731,361 - 11,809,500 (+)NCBICelera
Cytogenetic Map9q12NCBI
UBR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38642,564,029 - 42,693,505 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl642,564,029 - 42,693,505 (+)EnsemblGRCh38hg38GRCh38
GRCh37642,531,767 - 42,661,243 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36642,640,036 - 42,766,889 (+)NCBINCBI36Build 36hg18NCBI36
Celera644,084,013 - 44,213,528 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef642,250,154 - 42,379,642 (+)NCBIHuRef
CHM1_1642,534,602 - 42,663,798 (+)NCBICHM1_1
T2T-CHM13v2.0642,392,486 - 42,521,935 (+)NCBIT2T-CHM13v2.0
Ubr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391747,239,217 - 47,321,812 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1747,239,221 - 47,321,482 (-)EnsemblGRCm39 Ensembl
GRCm381746,928,291 - 47,010,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,928,295 - 47,010,556 (-)EnsemblGRCm38mm10GRCm38
MGSCv371747,065,240 - 47,147,481 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361746,391,482 - 46,473,684 (-)NCBIMGSCv36mm8
Celera1750,364,557 - 50,446,007 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.91NCBI
Ubr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554378,677,801 - 8,782,120 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554378,678,212 - 8,780,700 (+)NCBIChiLan1.0ChiLan1.0
UBR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,058,201 - 57,190,366 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1652,928,203 - 53,058,177 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,150,409 - 42,282,486 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1643,449,154 - 43,579,224 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl643,449,154 - 43,579,224 (+)Ensemblpanpan1.1panPan2
UBR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,167,286 - 11,296,817 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1211,167,346 - 11,294,911 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,194,238 - 11,324,038 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01211,648,206 - 11,778,081 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1211,648,320 - 11,778,079 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11211,176,544 - 11,306,317 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01211,261,325 - 11,391,207 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01211,354,858 - 11,484,875 (+)NCBIUU_Cfam_GSD_1.0
Ubr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494646,637,679 - 46,781,221 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647617,181,214 - 17,322,163 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647617,178,981 - 17,322,600 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl737,655,926 - 37,784,359 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1737,655,808 - 37,785,301 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,111,597 - 43,215,426 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11729,458,388 - 29,590,706 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1729,458,374 - 29,590,687 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604442,587,479 - 42,725,323 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ubr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475416,701,331 - 16,798,897 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475416,701,950 - 16,798,293 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ubr2
318 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:24
Count of miRNA genes:24
Interacting mature miRNAs:24
Transcripts:ENSRNOT00000021158
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat

Markers in Region
D9Rat40  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2914,013,840 - 14,013,932 (+)MAPPERmRatBN7.2
Rnor_6.0916,034,318 - 16,034,409NCBIRnor6.0
Rnor_5.0914,950,723 - 14,950,814UniSTSRnor5.0
RGSC_v3.499,196,789 - 9,196,880UniSTSRGSC3.4
RGSC_v3.499,196,788 - 9,196,880RGDRGSC3.4
RGSC_v3.199,194,111 - 9,194,202RGD
Celera911,763,068 - 11,763,159UniSTS
RH 3.4 Map953.1RGD
RH 3.4 Map953.1UniSTS
RH 2.0 Map955.5RGD
SHRSP x BN Map911.8399RGD
FHH x ACI Map96.94RGD
Cytogenetic Map9q12UniSTS
RH127717  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2914,062,015 - 14,062,200 (+)MAPPERmRatBN7.2
Rnor_6.0916,081,800 - 16,081,984NCBIRnor6.0
Rnor_5.0914,998,683 - 14,998,867UniSTSRnor5.0
RGSC_v3.499,246,962 - 9,247,146UniSTSRGSC3.4
Celera911,811,148 - 11,811,332UniSTS
RH 3.4 Map960.3UniSTS
Cytogenetic Map9q12UniSTS
RH128056  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2914,032,170 - 14,032,384 (+)MAPPERmRatBN7.2
Rnor_6.0916,052,646 - 16,052,859NCBIRnor6.0
Rnor_5.0914,969,051 - 14,969,264UniSTSRnor5.0
RGSC_v3.499,215,117 - 9,215,330UniSTSRGSC3.4
Celera911,781,396 - 11,781,609UniSTS
RH 3.4 Map955.7UniSTS
Cytogenetic Map9q12UniSTS
RH143201  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2914,060,552 - 14,060,693 (+)MAPPERmRatBN7.2
Rnor_6.0916,080,337 - 16,080,477NCBIRnor6.0
Rnor_5.0914,997,220 - 14,997,360UniSTSRnor5.0
RGSC_v3.499,245,499 - 9,245,639UniSTSRGSC3.4
Celera911,809,685 - 11,809,825UniSTS
RH 3.4 Map959.4UniSTS
Cytogenetic Map9q12UniSTS
RH138826  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2914,060,552 - 14,060,768 (+)MAPPERmRatBN7.2
Rnor_6.0916,080,337 - 16,080,552NCBIRnor6.0
Rnor_5.0914,997,220 - 14,997,435UniSTSRnor5.0
RGSC_v3.499,245,499 - 9,245,714UniSTSRGSC3.4
Celera911,809,685 - 11,809,900UniSTS
RH 3.4 Map955.0UniSTS
Cytogenetic Map9q12UniSTS
BF390989  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2914,019,516 - 14,019,722 (+)MAPPERmRatBN7.2
Rnor_6.0916,039,994 - 16,040,199NCBIRnor6.0
Rnor_5.0914,956,399 - 14,956,604UniSTSRnor5.0
RGSC_v3.499,202,465 - 9,202,670UniSTSRGSC3.4
Celera911,768,744 - 11,768,949UniSTS
RH 3.4 Map957.3UniSTS
Cytogenetic Map9q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 36 11 8
Low 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000021158   ⟹   ENSRNOP00000021158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl913,982,329 - 14,058,922 (+)Ensembl
Rnor_6.0 Ensembl916,003,058 - 16,080,152 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000081621   ⟹   ENSRNOP00000071986
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl913,982,329 - 14,058,922 (+)Ensembl
Rnor_6.0 Ensembl916,003,058 - 16,072,988 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094973   ⟹   ENSRNOP00000078618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl913,982,684 - 14,060,495 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100833   ⟹   ENSRNOP00000077068
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl913,982,684 - 14,060,495 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111742   ⟹   ENSRNOP00000076741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl913,982,329 - 14,062,139 (+)Ensembl
RefSeq Acc Id: NM_001178071   ⟹   NP_001171542
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8921,480,117 - 21,559,936 (+)NCBI
mRatBN7.2913,982,491 - 14,062,315 (+)NCBI
Rnor_6.0916,003,058 - 16,080,152 (+)NCBI
Rnor_5.0914,919,790 - 14,997,035 (+)NCBI
Celera911,731,361 - 11,809,500 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001412818   ⟹   NP_001399747
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8921,480,117 - 21,559,936 (+)NCBI
mRatBN7.2913,982,491 - 14,062,315 (+)NCBI
RefSeq Acc Id: XM_039083816   ⟹   XP_038939744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8921,480,064 - 21,559,936 (+)NCBI
mRatBN7.2913,982,432 - 14,062,315 (+)NCBI
RefSeq Acc Id: XM_039083820   ⟹   XP_038939748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8921,480,058 - 21,530,164 (+)NCBI
mRatBN7.2913,982,427 - 14,032,542 (+)NCBI
RefSeq Acc Id: XM_063267355   ⟹   XP_063123425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8921,480,064 - 21,559,936 (+)NCBI
RefSeq Acc Id: XM_063267356   ⟹   XP_063123426
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8921,520,181 - 21,559,936 (+)NCBI
RefSeq Acc Id: XM_063267357   ⟹   XP_063123427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8921,480,058 - 21,530,164 (+)NCBI
RefSeq Acc Id: XR_010054612
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8921,480,063 - 21,553,197 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001171542   ⟸   NM_001178071
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: ENSRNOP00000021158   ⟸   ENSRNOT00000021158
RefSeq Acc Id: ENSRNOP00000071986   ⟸   ENSRNOT00000081621
RefSeq Acc Id: XP_038939748   ⟸   XM_039083820
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038939744   ⟸   XM_039083816
- Peptide Label: isoform X1
- UniProtKB: D5MTH0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000078618   ⟸   ENSRNOT00000094973
RefSeq Acc Id: ENSRNOP00000077068   ⟸   ENSRNOT00000100833
RefSeq Acc Id: ENSRNOP00000076741   ⟸   ENSRNOT00000111742
RefSeq Acc Id: NP_001399747   ⟸   NM_001412818
- Peptide Label: isoform 1
- UniProtKB: A0A8I5YBG5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123427   ⟸   XM_063267357
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063123425   ⟸   XM_063267355
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063123426   ⟸   XM_063267356
- Peptide Label: isoform X3
Protein Domains
UBR-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9U6-F1-model_v2 AlphaFold D4A9U6 1-1755 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593237 AgrOrtholog
BioCyc Gene G2FUF-28254 BioCyc
Ensembl Genes ENSRNOG00000015813 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021158.8 UniProtKB/TrEMBL
  ENSRNOT00000081621 ENTREZGENE
  ENSRNOT00000081621.2 UniProtKB/TrEMBL
  ENSRNOT00000094973.1 UniProtKB/TrEMBL
  ENSRNOT00000100833.1 UniProtKB/TrEMBL
  ENSRNOT00000111742 ENTREZGENE
  ENSRNOT00000111742.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.2670 UniProtKB/TrEMBL
  2.10.110.30 UniProtKB/TrEMBL
  3.30.1390.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7308717 IMAGE-MGC_LOAD
InterPro ClpS_core UniProtKB/TrEMBL
  E3_ELL-like UniProtKB/TrEMBL
  E3_ligase_UBR-like_C UniProtKB/TrEMBL
  Ribosomal_L7/12_C/ClpS-like UniProtKB/TrEMBL
  UBR-box_UBR2 UniProtKB/TrEMBL
  UBR1-like UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
  Znf_N-recognin UniProtKB/TrEMBL
KEGG Report rno:363188 UniProtKB/TrEMBL
MGC_CLONE MGC:125135 IMAGE-MGC_LOAD
NCBI Gene 363188 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE UBR2 UniProtKB/TrEMBL
  PTHR21497 UniProtKB/TrEMBL
Pfam ClpS UniProtKB/TrEMBL
  PRT6_C UniProtKB/TrEMBL
  zf-UBR UniProtKB/TrEMBL
PhenoGen Ubr2 PhenoGen
PROSITE ZF_UBR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015813 RatGTEx
SMART ZnF_UBR1 UniProtKB/TrEMBL
Superfamily-SCOP Ribosomal_L7/12_C/ClpS-like UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
UniProt A0A0G2K1U4_RAT UniProtKB/TrEMBL
  A0A8I5XVR7_RAT UniProtKB/TrEMBL
  A0A8I5YBG5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZL62_RAT UniProtKB/TrEMBL
  D4A9U6_RAT UniProtKB/TrEMBL
  D5MTH0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-11-16 Ubr2  ubiquitin protein ligase E3 component n-recognin 2  LOC363188  similar to ubiquitin protein ligase E3 component n-recognin 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC363188  similar to ubiquitin protein ligase E3 component n-recognin 2      Symbol and Name status set to provisional 70820 PROVISIONAL