Prr23d1 (proline rich 23 domain containing 1) - Rat Genome Database

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Gene: Prr23d1 (proline rich 23 domain containing 1) Rattus norvegicus
Analyze
Symbol: Prr23d1
Name: proline rich 23 domain containing 1
RGD ID: 1592646
Description: ASSOCIATED WITH genetic disease (ortholog); INTERACTS WITH benzo[a]pyrene (ortholog); bisphenol A (ortholog); valproic acid (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC685501; LOC685501; proline-rich protein 23A3-like
RGD Orthologs
Human
Bonobo
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,351,972 - 108,352,688 (+)NCBIGRCr8
mRatBN7.2899,472,587 - 99,473,303 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,472,587 - 99,473,303 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.08107,155,003 - 107,156,241 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8107,155,220 - 107,155,930 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08106,580,155 - 106,580,871 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,763,194 - 103,763,910 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera898,877,984 - 98,879,222 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Prr23d1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,351,972 - 108,352,688 (+)NCBIGRCr8
mRatBN7.2899,472,587 - 99,473,303 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,472,587 - 99,473,303 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.08107,155,003 - 107,156,241 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8107,155,220 - 107,155,930 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08106,580,155 - 106,580,871 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,763,194 - 103,763,910 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera898,877,984 - 98,879,222 (+)NCBICelera
Cytogenetic Map8q31NCBI
PRR23C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383139,042,102 - 139,044,892 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3139,042,102 - 139,044,892 (-)EnsemblGRCh38hg38GRCh38
GRCh373138,760,944 - 138,763,734 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,245,364 - 140,246,418 (-)NCBINCBI36Build 36hg18NCBI36
Celera3137,187,214 - 137,190,001 (-)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3136,136,298 - 136,139,085 (-)NCBIHuRef
CHM1_13138,725,238 - 138,728,025 (-)NCBICHM1_1
T2T-CHM13v2.03141,783,116 - 141,785,903 (-)NCBIT2T-CHM13v2.0
PRR23C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22136,951,315 - 136,955,018 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13136,956,044 - 136,960,109 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03136,074,879 - 136,078,681 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13143,676,488 - 143,677,150 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3143,676,488 - 143,677,217 (-)Ensemblpanpan1.1panPan2
LOC110256523
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11379,795,592 - 79,797,974 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

Variants

.
Variants in Prr23d1
1 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system integumental system musculoskeletal system reproductive system appendage
High
Medium
Low 4
Below cutoff 1 3 1 1 12 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000085024   ⟹   ENSRNOP00000073039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl899,472,587 - 99,473,303 (+)Ensembl
Rnor_6.0 Ensembl8107,155,220 - 107,155,930 (+)Ensembl
RefSeq Acc Id: NM_001408792   ⟹   NP_001395721
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88108,351,972 - 108,352,688 (+)NCBI
mRatBN7.2899,472,587 - 99,473,303 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001395721 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073039.2
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000073039   ⟸   ENSRNOT00000085024
RefSeq Acc Id: NP_001395721   ⟸   NM_001408792

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K4G9-F1-model_v2 AlphaFold A0A0G2K4G9 1-183 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-29411 BioCyc
Ensembl Genes ENSRNOG00000061716 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000085024.2 UniProtKB/TrEMBL
InterPro PRR23 UniProtKB/TrEMBL
NCBI Gene 685501 ENTREZGENE
PANTHER PROLINE-RICH PROTEIN 23B UniProtKB/TrEMBL
  RIKEN CDNA 7420426K07 GENE UniProtKB/TrEMBL
Pfam DUF2476 UniProtKB/TrEMBL
PhenoGen Prr23d1 PhenoGen
RatGTEx ENSRNOG00000061716 RatGTEx
UniProt A0A0G2K4G9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-24 Prr23d1  proline rich 23 domain containing 1  LOC685501  hypothetical protein LOC685501  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC685501  hypothetical protein LOC685501      Symbol and Name status set to provisional 70820 PROVISIONAL