Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TRAPPC6A mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Trappc6a (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TRAPPC6A mRNA | CTD | PMID:36331819 | 17beta-estradiol | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Estradiol results in decreased expression of TRAPPC6A mRNA | CTD | PMID:23019147 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Trappc6a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TRAPPC6A mRNA | CTD | PMID:21570461 and PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TRAPPC6A mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2-hydroxypropanoic acid | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TRAPPC6A mRNA | CTD | PMID:30851411 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TRAPPC6A mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of TRAPPC6A mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of TRAPPC6A mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Trappc6a (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of TRAPPC6A promoter | CTD | PMID:33297965 | acetylsalicylic acid | increases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Aspirin results in increased expression of TRAPPC6A mRNA | CTD | PMID:11906190 | acrylamide | affects expression | EXP | | 6480464 | Acrylamide affects the expression of TRAPPC6A mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of TRAPPC6A mRNA | CTD | PMID:32763439 | acrylamide | affects methylation | ISO | Trappc6a (Mus musculus) | 6480464 | Acrylamide affects the methylation of TRAPPC6A gene | CTD | PMID:35032568 | aflatoxin B1 | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of TRAPPC6A mRNA | CTD | PMID:22100608 | aristolochic acid A | increases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TRAPPC6A mRNA | CTD | PMID:33212167 | arsane | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TRAPPC6A mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TRAPPC6A mRNA | CTD | PMID:32525701 | atrazine | increases expression | EXP | | 6480464 | Atrazine results in increased expression of TRAPPC6A mRNA | CTD | PMID:36841081 | benzo[a]pyrene | multiple interactions | ISO | Trappc6a (Mus musculus) | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to TRAPPC6A promoter] | CTD | PMID:19654925 | benzo[a]pyrene | affects methylation | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TRAPPC6A intron | CTD | PMID:30157460 | benzo[a]pyrene | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TRAPPC6A mRNA | CTD | PMID:26238291 and PMID:32234424 | benzo[e]pyrene | decreases methylation | ISO | TRAPPC6A (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of TRAPPC6A intron | CTD | PMID:30157460 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TRAPPC6A mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Trappc6a (Mus musculus) | 6480464 | bisphenol A results in increased expression of TRAPPC6A mRNA | CTD | PMID:32156529 and PMID:33221593 | bisphenol A | increases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | bisphenol A results in increased expression of TRAPPC6A mRNA | CTD | PMID:29275510 | bisphenol A | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TRAPPC6A mRNA | CTD | PMID:28628672 | carbamazepine | affects expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Carbamazepine affects the expression of TRAPPC6A mRNA | CTD | PMID:25979313 | carbon nanotube | decreases expression | ISO | Trappc6a (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlorpyrifos | increases expression | ISO | Trappc6a (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of TRAPPC6A mRNA | CTD | PMID:37019170 | cisplatin | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of TRAPPC6A mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of TRAPPC6A mRNA | CTD | PMID:19376846 | copper(II) sulfate | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of TRAPPC6A mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TRAPPC6A mRNA | CTD | PMID:25562108 | cyfluthrin | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Melatonin inhibits the reaction [cyfluthrin results in decreased expression of TRAPPC6A mRNA] | CTD | PMID:31330490 | cyfluthrin | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | cyfluthrin results in decreased expression of TRAPPC6A mRNA | CTD | PMID:31330490 | dexamethasone | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TRAPPC6A mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of TRAPPC6A mRNA | CTD | PMID:28628672 | dicrotophos | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of TRAPPC6A mRNA | CTD | PMID:28302478 | dorsomorphin | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | fluoranthene | multiple interactions | ISO | Trappc6a (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of TRAPPC6A mRNA | CTD | PMID:28329830 | folic acid | increases expression | ISO | Trappc6a (Mus musculus) | 6480464 | Folic Acid results in increased expression of TRAPPC6A mRNA | CTD | PMID:25629700 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of TRAPPC6A gene | CTD | PMID:22079235 | glyphosate | decreases methylation | EXP | | 6480464 | Glyphosate results in decreased methylation of TRAPPC6A gene | CTD | PMID:31011160 | hydralazine | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of TRAPPC6A mRNA | CTD | PMID:17183730 | indometacin | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TRAPPC6A mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of TRAPPC6A mRNA | CTD | PMID:28628672 | inulin | multiple interactions | ISO | Trappc6a (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TRAPPC6A mRNA | CTD | PMID:36331819 | lipopolysaccharide | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [Lipopolysaccharides co-treated with resveratrol] results in increased expression of TRAPPC6A mRNA | CTD | PMID:26667767 | melatonin | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Melatonin inhibits the reaction [cyfluthrin results in decreased expression of TRAPPC6A mRNA] | CTD | PMID:31330490 | mercury dibromide | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | mercuric bromide results in decreased expression of TRAPPC6A mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TRAPPC6A mRNA | CTD | PMID:27188386 | methapyrilene | decreases methylation | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of TRAPPC6A intron | CTD | PMID:30157460 | methylmercury chloride | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of TRAPPC6A mRNA | CTD | PMID:28001369 | nickel atom | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Nickel results in decreased expression of TRAPPC6A mRNA | CTD | PMID:24768652 and PMID:25583101 | paracetamol | affects expression | ISO | Trappc6a (Mus musculus) | 6480464 | Acetaminophen affects the expression of TRAPPC6A mRNA | CTD | PMID:17562736 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Trappc6a (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TRAPPC6A mRNA more ... | CTD | PMID:36331819 | phenylmercury acetate | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of TRAPPC6A mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TRAPPC6A mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | ISO | Trappc6a (Mus musculus) | 6480464 | pirinixic acid results in increased expression of TRAPPC6A mRNA | CTD | PMID:18301758 and PMID:23811191 | quercetin | increases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Quercetin results in increased expression of TRAPPC6A mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TRAPPC6A mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [Lipopolysaccharides co-treated with resveratrol] results in increased expression of TRAPPC6A mRNA | CTD | PMID:26667767 | rotenone | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Rotenone results in decreased expression of TRAPPC6A mRNA | CTD | PMID:29955902 | SB 431542 | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of TRAPPC6A mRNA | CTD | PMID:25895662 | sodium arsenate | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TRAPPC6A mRNA | CTD | PMID:32525701 | sodium arsenite | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [CARM1 mutant form co-treated with sodium arsenite] results in increased expression of TRAPPC6A mRNA and [PRMT1 mutant form co-treated with sodium arsenite] results in increased expression of TRAPPC6A mRNA | CTD | PMID:23699174 | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of TRAPPC6A mRNA | CTD | PMID:22110744 | temozolomide | decreases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of TRAPPC6A mRNA | CTD | PMID:31758290 | testosterone enanthate | affects expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of TRAPPC6A mRNA | CTD | PMID:17440010 | tetrachloroethene | decreases expression | ISO | Trappc6a (Mus musculus) | 6480464 | Tetrachloroethylene results in decreased expression of TRAPPC6A mRNA | CTD | PMID:28973375 | tetrachloromethane | affects expression | ISO | Trappc6a (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of TRAPPC6A mRNA | CTD | PMID:17484886 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TRAPPC6A mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TRAPPC6A mRNA | CTD | PMID:31150632 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TRAPPC6A mRNA | CTD | PMID:34492290 | triptonide | increases expression | ISO | Trappc6a (Mus musculus) | 6480464 | triptonide results in increased expression of TRAPPC6A mRNA | CTD | PMID:33045310 | tunicamycin | increases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of TRAPPC6A mRNA | CTD | PMID:29453283 | valproic acid | increases methylation | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TRAPPC6A gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TRAPPC6A mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | TRAPPC6A (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of TRAPPC6A mRNA | CTD | PMID:17183730 | valproic acid | increases expression | ISO | TRAPPC6A (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TRAPPC6A mRNA | CTD | PMID:29154799 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of TRAPPC6A mRNA | CTD | PMID:22570695 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of TRAPPC6A mRNA | CTD | PMID:23034163 | |