Exoc1l (exocyst complex component 1 like) - Rat Genome Database

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Gene: Exoc1l (exocyst complex component 1 like) Rattus norvegicus
Analyze
Symbol: Exoc1l
Name: exocyst complex component 1 like
RGD ID: 1591303
Description: Orthologous to human EXOC1L (exocyst complex component 1 like); INTERACTS WITH 4,4'-sulfonyldiphenol (ortholog); benzo[a]pyrene (ortholog); lipopolysaccharide (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: exocyst complex component 1-like; LOC686911; similar to Exocyst complex component 1 (Exocyst complex component Sec3)
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81432,027,702 - 32,062,413 (-)NCBIGRCr8
mRatBN7.21431,673,465 - 31,698,175 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1431,673,636 - 31,698,001 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1432,050,583 - 32,075,210 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01433,358,470 - 33,383,097 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01431,843,587 - 31,868,216 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01434,192,155 - 34,219,497 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1434,194,217 - 34,218,961 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01433,971,786 - 33,997,807 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1430,985,045 - 31,011,970 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Comparative Map Data
Exoc1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81432,027,702 - 32,062,413 (-)NCBIGRCr8
mRatBN7.21431,673,465 - 31,698,175 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1431,673,636 - 31,698,001 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1432,050,583 - 32,075,210 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01433,358,470 - 33,383,097 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01431,843,587 - 31,868,216 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01434,192,155 - 34,219,497 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1434,194,217 - 34,218,961 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01433,971,786 - 33,997,807 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1430,985,045 - 31,011,970 (-)NCBICelera
Cytogenetic Map14p11NCBI
EXOC1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38455,819,790 - 55,837,489 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl455,819,790 - 55,837,489 (+)EnsemblGRCh38hg38GRCh38
GRCh37456,685,956 - 56,703,655 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36456,380,950 - 56,398,274 (+)NCBINCBI36Build 36hg18NCBI36
Celera454,192,629 - 54,209,824 (+)NCBICelera
Cytogenetic Map4q12NCBI
HuRef452,640,110 - 52,657,305 (+)NCBIHuRef
CHM1_1456,721,385 - 56,738,581 (+)NCBICHM1_1
T2T-CHM13v2.0459,307,935 - 59,325,634 (+)NCBIT2T-CHM13v2.0
Exoc1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39576,631,924 - 76,664,475 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl576,631,887 - 76,664,496 (+)EnsemblGRCm39 Ensembl
GRCm38576,484,077 - 76,516,628 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl576,484,040 - 76,516,649 (+)EnsemblGRCm38mm10GRCm38
MGSCv37576,913,102 - 76,945,653 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36577,559,106 - 77,591,359 (+)NCBIMGSCv36mm8
Celera573,752,158 - 73,784,597 (+)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map541.23NCBI
EXOC1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2373,948,069 - 73,966,021 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1474,153,524 - 74,171,478 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0468,091,792 - 68,109,741 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1474,659,663 - 74,677,206 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl474,659,694 - 74,677,067 (-)Ensemblpanpan1.1panPan2
EXOC1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11348,073,183 - 48,090,042 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1348,073,596 - 48,089,911 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1347,965,050 - 47,982,159 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01348,687,409 - 48,704,529 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1348,687,348 - 48,703,959 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11348,361,811 - 48,378,978 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01347,888,957 - 47,906,468 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01348,835,448 - 48,852,591 (+)NCBIUU_Cfam_GSD_1.0
Exoc1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528528,162,633 - 28,182,209 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648218,116,452 - 18,133,056 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648218,116,469 - 18,133,227 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC106504669
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl855,139,725 - 55,156,575 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1855,139,783 - 55,156,700 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2858,404,588 - 58,421,358 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EXOC1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1712,777,613 - 12,796,257 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606613,449,616 - 13,467,351 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Exoc1l
189 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:57
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000072588
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141759376142336881Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141762256142337007Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141863134542337007Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
2324617Coatc2Coat color QTL 20.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)143076702539153750Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat

Markers in Region
D14Rat117  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21431,680,383 - 31,680,527 (+)MAPPERmRatBN7.2
Rnor_6.01434,201,342 - 34,201,485NCBIRnor6.0
Rnor_5.01433,979,176 - 33,979,319UniSTSRnor5.0
RGSC_v3.41433,954,109 - 33,954,253RGDRGSC3.4
RGSC_v3.41433,954,110 - 33,954,253UniSTSRGSC3.4
RGSC_v3.11433,954,109 - 33,954,253RGD
Celera1430,993,851 - 30,993,994UniSTS
SHRSP x BN Map1421.5399RGD
SHRSP x BN Map1421.5399UniSTS
AU046793  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21431,675,803 - 31,676,008 (+)MAPPERmRatBN7.2
Rnor_6.01434,196,766 - 34,196,966NCBIRnor6.0
Rnor_5.01433,974,600 - 33,974,800UniSTSRnor5.0
RGSC_v3.41433,949,534 - 33,949,734UniSTSRGSC3.4
Celera1430,989,275 - 30,989,475UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system nervous system reproductive system respiratory system
High
Medium
Low 19 5
Below cutoff 3 2 1 1 2 1 45 8 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000072588   ⟹   ENSRNOP00000064483
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1431,673,636 - 31,698,001 (-)Ensembl
Rnor_6.0 Ensembl1434,194,217 - 34,218,961 (-)Ensembl
RefSeq Acc Id: NM_001399551   ⟹   NP_001386480
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81432,027,702 - 32,052,405 (-)NCBI
mRatBN7.21431,673,465 - 31,698,175 (-)NCBI
RefSeq Acc Id: XM_063273631   ⟹   XP_063129701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81432,027,705 - 32,062,413 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001386480 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129701 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064483
  ENSRNOP00000064483.1
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000064483   ⟸   ENSRNOT00000072588
RefSeq Acc Id: NP_001386480   ⟸   NM_001399551
- UniProtKB: M0R528 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129701   ⟸   XM_063273631
- Peptide Label: isoform X1
Protein Domains
Exocyst complex component Sec3 PIP2-binding N-

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R528-F1-model_v2 AlphaFold M0R528 1-172 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591303 AgrOrtholog
BioCyc Gene G2FUF-15948 BioCyc
Ensembl Genes ENSRNOG00000050100 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072588 ENTREZGENE
  ENSRNOT00000072588.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.90 UniProtKB/TrEMBL
InterPro Sec3-PIP2_bind UniProtKB/TrEMBL
KEGG Report rno:686911 UniProtKB/TrEMBL
NCBI Gene 686911 ENTREZGENE
Pfam Sec3-PIP2_bind UniProtKB/TrEMBL
PhenoGen Exoc1l PhenoGen
RatGTEx ENSRNOG00000050100 RatGTEx
SMART Sec3-PIP2_bind UniProtKB/TrEMBL
UniProt A6JCX9_RAT UniProtKB/TrEMBL
  M0R528 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-11-08 Exoc1l  exocyst complex component 1 like  LOC686911  similar to Exocyst complex component 1 (Exocyst complex component Sec3)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC686911  similar to Exocyst complex component 1 (Exocyst complex component Sec3)      Symbol and Name status set to provisional 70820 PROVISIONAL