Rpl14l2 (ribosomal protein L14 like 2) - Rat Genome Database

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Gene: Rpl14l2 (ribosomal protein L14 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rpl14l2 (Ensembl: LOC680579)
Name: ribosomal protein L14 like 2 (Ensembl:similar to ribosomal protein L14)
RGD ID: 1590581
Description: Predicted to be involved in translation. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Orthologous to human RPL14 (ribosomal protein L14).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 60S ribosomal protein L14-like; AABR07014996.1; large ribosomal subunit protein eL14-like; LOC680579; ribosomal protein L14 like 1; Rpl14l1; similar to ribosomal protein L14
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81442,947,085 - 42,949,752 (-)NCBIGRCr8
mRatBN7.21442,594,039 - 42,594,681 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,594,039 - 42,594,665 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01444,224,567 - 44,226,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,225,087 - 44,225,713 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01444,044,687 - 44,045,424 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,284,854 - 45,285,480 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1441,744,584 - 41,746,226 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rpl14l2
2 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000049161   ⟹   ENSRNOP00000060476
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1442,594,039 - 42,594,665 (-)Ensembl
RefSeq Acc Id: XM_063273825   ⟹   XP_063129895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81442,947,085 - 42,949,752 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063129895 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000060476.1
RefSeq Acc Id: ENSRNOP00000060476   ⟸   ENSRNOT00000049161
RefSeq Acc Id: XP_063129895   ⟸   XM_063273825
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHE6-F1-model_v2 AlphaFold D3ZHE6 1-208 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1590581 AgrOrtholog
BioCyc Gene G2FUF-15750 BioCyc
Ensembl Genes ENSRNOG00000032160 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000049161.4 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.30 UniProtKB/TrEMBL
  6.10.250.2270 UniProtKB/TrEMBL
InterPro Rib_L2_dom2 UniProtKB/TrEMBL
  Ribosomal_L14e_dom UniProtKB/TrEMBL
  Ribosomal_protein_L14 UniProtKB/TrEMBL
  RPL14_KOW UniProtKB/TrEMBL
  Translation_prot_SH3-like_sf UniProtKB/TrEMBL
NCBI Gene 680579 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L14 UniProtKB/TrEMBL
  PTHR11127 UniProtKB/TrEMBL
Pfam Ribosomal_L14e UniProtKB/TrEMBL
PhenoGen Rpl14l2 PhenoGen
RatGTEx ENSRNOG00000032160 RatGTEx
Superfamily-SCOP SSF50104 UniProtKB/TrEMBL
UniProt D3ZHE6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-13 Rpl14l2  ribosomal protein L14 like 2  Rpl14l1  ribosomal protein L14 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Rpl14l1  ribosomal protein L14 like 1  LOC680579  similar to ribosomal protein L14  Symbol and Name Changed 1299863 APPROVED
2022-06-02 LOC680579  similar to ribosomal protein L14  AABR07014996.1    Data merged from RGD:15003936 737654 PROVISIONAL
2019-11-08 AABR07014996.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2008-01-09 LOC680579  similar to ribosomal protein L14  LOC686540  similar to ribosomal protein L14  Data merged from RGD:1596358 1643240 APPROVED
2006-11-20 LOC680579  similar to ribosomal protein L14      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC686540  similar to ribosomal protein L14      Symbol and Name status set to provisional 70820 PROVISIONAL