Gene: Vps35 (VPS35 retromer complex component) Rattus norvegicus
Symbol: Vps35
Name: VPS35 retromer complex component
Description: INVOLVED IN negative regulation of late endosome to lysosome transport (ortholog); positive regulation of canonical Wnt signaling pathway (ortholog); positive regulation of Wnt protein secretion (ortholog); PARTICIPATES IN altered retromer-mediated pathway; Parkinson disease pathway; retromer-mediated pathway; ASSOCIATED WITH Abnormalities, Multiple (ortholog); Parkinson Disease (ortholog); Parkinson Disease 17 (ortholog); FOUND IN retromer complex; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH benzo[a]pyrene; bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Maternal embryonic message 3; Mem3; vacuolar protein sorting 35; vacuolar protein sorting 35 (mapped); vacuolar protein sorting 35 homolog; vacuolar protein sorting 35 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 35; Vps35_mapped
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01927,464,937 - 27,500,636+NCBI
Rat Cytogenetic Map19q11 NCBI
RGSC Genome Assembly v5.01938,430,733 - 38,466,263+NCBI
RGSC Genome Assembly v3.41923,124,790 - 23,161,655+NCBI
Rat Celera Assembly1921,625,446 - 21,661,413+NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Vps35
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1589784
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2016-02-02
Status: ACTIVE