Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Fhod1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of FHOD1 mRNA] | CTD | PMID:22206623 | 1,2-dimethylhydrazine | increases expression | ISO | Fhod1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of FHOD1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | FHOD1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of FHOD1 mRNA | CTD | PMID:30165855 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of FHOD1 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fhod1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FHOD1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FHOD1 mRNA | CTD | PMID:34747641 | 2,4,6-tribromophenol | increases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2-methylcholine | affects expression | ISO | FHOD1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of FHOD1 mRNA | CTD | PMID:21179406 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:32119087 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of FHOD1 protein | CTD | PMID:31675489 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | FHOD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FHOD1 mRNA | CTD | PMID:28628672 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of FHOD1 mRNA | CTD | PMID:30047161 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of FHOD1 mRNA | CTD | PMID:31881176 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of FHOD1 mRNA | CTD | PMID:30047161 | aristolochic acid A | increases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of FHOD1 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | FHOD1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of FHOD1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | FHOD1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of FHOD1 gene | CTD | PMID:25304211 | arsenous acid | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of FHOD1 mRNA | CTD | PMID:20458559 | benzo[a]pyrene | decreases methylation | ISO | Fhod1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of FHOD1 exon and Benzo(a)pyrene results in decreased methylation of FHOD1 intron | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | FHOD1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of FHOD1 promoter | CTD | PMID:27901495 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FHOD1 mRNA | CTD | PMID:25181051 and PMID:31129395 | bisphenol A | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of FHOD1 protein | CTD | PMID:31675489 | bisphenol A | decreases methylation | ISO | FHOD1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of FHOD1 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FHOD1 mRNA | CTD | PMID:32145629 and PMID:34947998 | bisphenol A | increases expression | ISO | Fhod1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of FHOD1 mRNA | CTD | PMID:33221593 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with tributyltin] results in increased expression of FHOD1 mRNA | CTD | PMID:31129395 | bisphenol A | multiple interactions | ISO | FHOD1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of FHOD1 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FHOD1 mRNA | CTD | PMID:28628672 and PMID:31601247 | bisphenol A | increases methylation | ISO | Fhod1 (Mus musculus) | 6480464 | bisphenol A results in increased methylation of FHOD1 promoter | CTD | PMID:27312807 | Bisphenol B | increases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of FHOD1 protein | CTD | PMID:34186270 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of FHOD1 mRNA | CTD | PMID:19167457 | caffeine | affects phosphorylation | ISO | FHOD1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of FHOD1 protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | ISO | Fhod1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of FHOD1 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | FHOD1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to FHOD1 gene] | CTD | PMID:28238834 | clozapine | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Clozapine results in decreased expression of FHOD1 protein | CTD | PMID:34122009 | cobalt dichloride | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of FHOD1 mRNA | CTD | PMID:19320972 | coumarin | decreases phosphorylation | ISO | FHOD1 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of FHOD1 protein | CTD | PMID:35688186 | cyclosporin A | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of FHOD1 mRNA | CTD | PMID:25562108 | decabromodiphenyl ether | increases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of FHOD1 protein | CTD | PMID:31675489 | dexamethasone | multiple interactions | ISO | FHOD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FHOD1 mRNA | CTD | PMID:28628672 | diarsenic trioxide | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of FHOD1 mRNA | CTD | PMID:20458559 | dibutyl phthalate | decreases expression | ISO | Fhod1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of FHOD1 mRNA | CTD | PMID:17361019 and PMID:21266533 | dioxygen | multiple interactions | ISO | Fhod1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of FHOD1 mRNA | CTD | PMID:30529165 | diuron | affects expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Diuron affects the expression of FHOD1 mRNA | CTD | PMID:35967413 | entinostat | increases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | entinostat results in increased expression of FHOD1 mRNA | CTD | PMID:27188386 | fenthion | decreases expression | ISO | Fhod1 (Mus musculus) | 6480464 | Fenthion results in decreased expression of FHOD1 mRNA | CTD | PMID:34813904 | folic acid | multiple interactions | ISO | Fhod1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of FHOD1 mRNA] | CTD | PMID:22206623 | FR900359 | decreases phosphorylation | ISO | FHOD1 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of FHOD1 protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | FHOD1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of FHOD1 gene | CTD | PMID:31601247 | indometacin | multiple interactions | ISO | FHOD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FHOD1 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of FHOD1 protein | CTD | PMID:32959892 | lead(0) | affects methylation | ISO | FHOD1 (Homo sapiens) | 6480464 | Lead affects the methylation of FHOD1 gene | CTD | PMID:31636367 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of FHOD1 mRNA | CTD | PMID:30047161 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of FHOD1 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | Fhod1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of FHOD1 mRNA | CTD | PMID:34911549 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Fhod1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of FHOD1 mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of FHOD1 protein | CTD | PMID:26879310 | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of FHOD1 mRNA | CTD | PMID:30047161 | sodium arsenite | increases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of FHOD1 mRNA | CTD | PMID:34032870 | sunitinib | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of FHOD1 mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of FHOD1 mRNA | CTD | PMID:31758290 | topotecan | increases expression | EXP | | 6480464 | Topotecan results in increased expression of FHOD1 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of FHOD1 mRNA | CTD | PMID:25729387 | tributylstannane | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with tributyltin] results in increased expression of FHOD1 mRNA | CTD | PMID:31129395 | triptonide | decreases expression | ISO | Fhod1 (Mus musculus) | 6480464 | triptonide results in decreased expression of FHOD1 mRNA | CTD | PMID:33045310 | tungsten | decreases expression | ISO | Fhod1 (Mus musculus) | 6480464 | Tungsten results in decreased expression of FHOD1 mRNA | CTD | PMID:30912803 | urethane | decreases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of FHOD1 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FHOD1 mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | FHOD1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of FHOD1 mRNA | CTD | PMID:25979313 | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of FHOD1 mRNA | CTD | PMID:19015723 | |