Krtap16-5 (keratin associated protein 16-5) - Rat Genome Database

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Gene: Krtap16-5 (keratin associated protein 16-5) Rattus norvegicus
Analyze
Symbol: Krtap16-5
Name: keratin associated protein 16-5
RGD ID: 1588263
Description: Predicted to be located in intermediate filament. Orthologous to several human genes including KRTAP19-3 (keratin associated protein 19-3); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC680703; keratin-associated protein 19-1; LOC680703
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81141,735,430 - 41,736,014 (-)NCBIGRCr8
mRatBN7.21128,249,212 - 28,249,796 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,249,212 - 28,249,796 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1136,933,424 - 36,934,008 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01129,633,452 - 29,634,036 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01128,814,985 - 28,815,569 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01128,899,792 - 28,900,376 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1128,899,792 - 28,900,376 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01132,518,932 - 32,519,516 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41128,774,731 - 28,775,315 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1127,964,542 - 27,965,126 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Krtap16-5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81141,735,430 - 41,736,014 (-)NCBIGRCr8
mRatBN7.21128,249,212 - 28,249,796 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,249,212 - 28,249,796 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1136,933,424 - 36,934,008 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01129,633,452 - 29,634,036 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01128,814,985 - 28,815,569 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01128,899,792 - 28,900,376 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1128,899,792 - 28,900,376 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01132,518,932 - 32,519,516 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41128,774,731 - 28,775,315 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1127,964,542 - 27,965,126 (-)NCBICelera
Cytogenetic Map11q11NCBI
KRTAP19-7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382130,560,875 - 30,561,314 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2130,560,875 - 30,561,314 (-)EnsemblGRCh38hg38GRCh38
GRCh372131,933,194 - 31,933,633 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362130,855,288 - 30,855,479 (-)NCBINCBI36Build 36hg18NCBI36
Build 342130,855,287 - 30,855,479NCBI
Celera2117,116,560 - 17,116,751 (-)NCBICelera
Cytogenetic Map21q22.11NCBI
HuRef2117,342,432 - 17,342,623 (-)NCBIHuRef
CHM1_12131,495,141 - 31,495,332 (-)NCBICHM1_1
T2T-CHM13v2.02128,926,825 - 28,927,264 (-)NCBIT2T-CHM13v2.0

Variants

.
Variants in Krtap16-5
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:13
Count of miRNA genes:13
Interacting mature miRNAs:13
Transcripts:ENSRNOT00000061606
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

integumental system musculoskeletal system renal system reproductive system appendage
High
Medium
Low 2 2 2
Below cutoff 1 1 2 3 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000061606   ⟹   ENSRNOP00000058323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1128,249,212 - 28,249,796 (-)Ensembl
Rnor_6.0 Ensembl1128,899,792 - 28,900,376 (-)Ensembl
RefSeq Acc Id: NM_001109424   ⟹   NP_001102894
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81141,735,430 - 41,736,014 (-)NCBI
mRatBN7.21128,249,212 - 28,249,796 (-)NCBI
Rnor_6.01128,899,792 - 28,900,376 (-)NCBI
Rnor_5.01132,518,932 - 32,519,516 (-)NCBI
RGSC_v3.41128,774,731 - 28,775,315 (-)RGD
Celera1127,964,542 - 27,965,126 (-)RGD
Sequence:
RefSeq Acc Id: XM_039088620   ⟹   XP_038944548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81141,735,678 - 41,735,965 (-)NCBI
mRatBN7.21128,249,460 - 28,249,747 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001102894 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944548 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM10673 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000058323
  ENSRNOP00000058323.3
Reference Protein Sequences
RefSeq Acc Id: NP_001102894   ⟸   NM_001109424
- UniProtKB: D3ZK72 (UniProtKB/TrEMBL),   A6JLA8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000058323   ⟸   ENSRNOT00000061606
RefSeq Acc Id: XP_038944548   ⟸   XM_039088620
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZK72-F1-model_v2 AlphaFold D3ZK72 1-95 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698035
Promoter ID:EPDNEW_R8559
Type:single initiation site
Name:Krtap16-5_1
Description:keratin associated protein 16-5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01128,900,380 - 28,900,440EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1588263 AgrOrtholog
BioCyc Gene G2FUF-22006 BioCyc
Ensembl Genes ENSRNOG00000040064 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061606 ENTREZGENE
  ENSRNOT00000061606.5 UniProtKB/TrEMBL
InterPro KRTAP UniProtKB/TrEMBL
KEGG Report rno:680703 UniProtKB/TrEMBL
NCBI Gene 680703 ENTREZGENE
PANTHER KERATIN-ASSOCIATED PROTEIN 19-3-RELATED UniProtKB/TrEMBL
  KERATIN-ASSOCIATED PROTEIN 19-3-RELATED UniProtKB/TrEMBL
Pfam KRTAP UniProtKB/TrEMBL
PhenoGen Krtap16-5 PhenoGen
RatGTEx ENSRNOG00000040064 RatGTEx
UniProt A6JLA8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZK72 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-07-08 Krtap16-5  keratin associated protein 16-5  LOC683602  hypothetical protein LOC683602  Data merged from RGD:1584549 1643240 APPROVED
2008-03-05 Krtap16-5  keratin associated protein 16-5  LOC680703  hypothetical protein LOC680703  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC680703  hypothetical protein LOC680703      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC683602  hypothetical protein LOC683602      Symbol and Name status set to provisional 70820 PROVISIONAL