LOC685964 (hypothetical protein LOC685964)

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Keyword

Gene: LOC685964 (hypothetical protein LOC685964) Rattus norvegicus

Symbol:

LOC685964

Name:

hypothetical protein LOC685964

Description:

INTERACTS WITH aflatoxin B1 (ortholog); fonofos (ortholog); parathion (ortholog)

Type:

protein-coding

RefSeq Status:

PREDICTED

Also known as:

hypothetical protein LOC685964; uncharacterized protein LOC685964

Orthologs:

Homo sapiens : C3orf22 (chromosome 3 open reading frame 22) HGNC
Mus musculus : BC048671 (cDNA sequence BC048671) MGI

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	4	q34		NCBI
RGSC Genome Assembly v5.0	4	186,758,874 - 186,763,368	+	NCBI
RGSC Genome Assembly v3.4	4	124,564,593 - 124,569,087	+	NCBI
Rat Celera Assembly	4	111,742,535 - 111,746,963	+	NCBI

Model

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Annotation (Toggle Detail/Summary View)

Gene-Chemical Interaction Annotations

References - curated

Genomics

Comparative Map Data

QTLs in Region (RGSC Genome Assembly v3.4)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303168	Bp330	Blood pressure QTL 330	4.25	.017	Blood pressure		4	456799	149181446	Rat
2316958	Gluco58	Glucose level QTL 58	10		Glucose level	postprandial	4	6690606	185398530	Rat
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		Hypothalamic-pituitary-adrenal axis	corticosterone post-stress	4	8819982	149560340	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		Mammary tumor susceptibility	estradiol-induced	4	41729583	159115617	Rat
1354612	Foco1	Food consumption QTL 1	8.87		Consumption level	food intake	4	41729771	151158666	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		Consumption level	saline intake	4	41729771	151158666	Rat
2312567	Glom19	Glomerulus QTL 19	1.9	.006	Renal pathology		4	43686352	149560340	Rat
1298082	Stresp4	Stress response QTL 4			Hormone level	corticosterone	4	47889730	149560340	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		Consumption level	alcohol preference	4	54828166	152570244	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	.0001	Consumption level	alcohol preference	4	54879077	127941994	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	.000016	Consumption level	saccharin preference	4	58421110	158108528	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	.00015	Consumption level	alcohol preference	4	58421110	158108528	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	.00003	Consumption level	alcohol preference	4	58421110	158108528	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		Joint/bone inflammation	inflammation score	4	60974346	130228614	Rat
1641919	Alc22	Alcohol consumption QTL 22		.0005	Consumption level	alcohol preference	4	62832008	127941994	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			Glucose level		4	63276741	160891592	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		.0003	Uvea inflammation score		4	69183301	134858710	Rat
631646	Stl4	Serum triglyceride level QTL 4	6.5	.0001	Lipid level	triglyceride	4	72160227	134858710	Rat
61476	Aia3	Adjuvant induced arthritis QTL 3	3.9		Joint/bone inflammation	arthritis severity	4	73972453	133939659	Rat
61406	Scwia1	Streptococcal cell wall induced arthritis QTL 1	2.3		Joint/bone inflammation	streptococcal cell wall induced	4	73972453	154937227	Rat
631662	Hcar2	Hepatocarcinoma resistance QTL 2	3.1	.0003	Liver tumor resistance	nodule volume	4	78035196	135074488	Rat
738015	Pia9	Pristane induced arthritis QTL 9	4.5	.048	Joint/bone inflammation	arthritis severity	4	81916057	126916057	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		Gland mass	pituitary	4	82700691	182307104	Rat
70177	Xhs1	X-ray hypersensitivity QTL 1	25.1		X-ray sensitivity		4	82861630	155893772	Rat
634334	Xhs3	X-ray hypersensitivity QTL 3	10		X-ray sensitivity		4	84355208	131969855	Rat
1582232	Gluco25	Glucose level QTL 25	3.6	.0023	Glucose level	uptake	4	84886545	151158853	Rat
1358202	Gluco11	Glucose level QTL 11	2.4	.02	Glucose level	uptake	4	85014031	171204531	Rat
1578662	Bss15	Bone structure and strength QTL 15	19.6		Bone structure	femoral neck width	4	89539438	134539438	Rat
1578670	Bss14	Bone structure and strength QTL 14	16.4		Bone structure	femoral neck trabecular area	4	89539438	134539438	Rat
1578655	Bmd11	Bone mineral density QTL 11	11		Bone mineral density	femoral neck total vBMD	4	93201451	138201451	Rat
634335	Anxrr16	Anxiety related response QTL 16	7.22		Anxiety response		4	93498821	171204377	Rat
631689	Scl4	Serum cholesterol level QTL 4	1.9	.008	Lipid level	cholesterol	4	96867443	141867443	Rat
61434	Cia3	Collagen induced arthritis QTL 3	4.8		Joint/bone inflammation	arthritis severity	4	104415843	149415843	Rat
737821	Hcar9	Hepatocarcinoma resistance QTL 9	3.7		Liver tumor resistance	nodule number	4	106554769	171204531	Rat
6478680	Anxrr29	Anxiety related response QTL 29		.00092	Anxiety response	open field inner locomotion	4	106808891	151808891	Rat
6478740	Anxrr39	Anxiety related response QTL 39		.07528	Anxiety response	open field inner locomotion	4	106808891	151808891	Rat
2302049	Pia32	Pristane induced arthritis QTL 32	5.1	.001	Joint/bone inflammation	pristane induced	4	107728559	152728559	Rat
731165	Uae21	Urinary albumin excretion QTL 21	2.4	.0001	Renal function	urine albumin level	4	108641841	153641841	Rat
1331759	Hrtrt13	Heart rate QTL 13	3.54628		Heart rate		4	111754988	172369380	Rat
1549832	Bss3	Bone structure and strength QTL 3	11		Bone structure	Femoral midshaft cortical area	4	112039347	157039347	Rat
7207480	Bss105	Bone structure and strength QTL 105	8.1		Bone structure	Femoral midshaft moment of inertia	4	112039347	157039347	Rat
6478760	Anxrr45	Anxiety related response QTL 45		.06717	Anxiety response	response in light-dark box	4	113136999	158136999	Rat
6478763	Anxrr46	Anxiety related response QTL 46		.07428	Anxiety response	response in light-dark box	4	113136999	158136999	Rat
1331802	Srn5	Serum renin concentration QTL 5	3.045		Renin concentration	serum	4	115896404	160896404	Rat
1300116	Hrtrt5	Heart rate QTL 5	3.76		Heart rate	salt-loaded	4	117887605	154283969	Rat
724535	Cm18	Cardiac mass QTL 18	2.6		Cardiac mass		4	121375269	166375269	Rat
2293840	Kiddil9	Kidney dilation QTL 9	2.9		Renal pathology	kidney dilation	4	122550935	151158853	Rat

Sequence

Nucleotide Sequences

Protein Sequences

Strain Variation

Strain Sequence Variants

ACI/Eur (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.5.9-r16 and GATK v1.3-14

ACI/N (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLID
Secondary Analysis:	SAP42 (Developed at RNAAS)
Breeder:	National Institutes of Health
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

BN-Lx (ICL)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Imperial College London (Dr Timothy Aitman)
Platform:	SOLID
Secondary Analysis:	BWA, GATK, Samtools
Breeder:	Academy of Sciences of the Czech Republic (Dr.Michal Pravenec)
Grant Information:	MC-A654-5QB00

BN-Lx (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Platform:	SOLID
Secondary Analysis:	SAP42 (Developed at RNAAS)
Breeder:	Academy of Sciences of the Czech Republic (Dr.Michal Pravenec)
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

BN/NHsdMcwi (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLID
Secondary Analysis:	SAP42 (Developed at RNAAS)
Breeder:	Medical College of Wisconsin
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

BN/SsN (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLID
Secondary Analysis:	SAP42 (Developed at RNAAS)
Breeder:	National Institutes of Health
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

Buf/N (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLID
Secondary Analysis:	SAP42 (Developed at RNAAS)
Breeder:	National Institutes of Health
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

COP/Crl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) Univiersity of Wisconsin (Jim Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.5.9-r16 and GATK v2.3-5
Breeder:	Charles River
Grant Information:	NIH (CA77876)

F344/N (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLID
Breeder:	National Institutes of Health
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.5.9-r16 and GATK v1.3-14

FHH/EurMcwi (MDC)

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Sequenced By:	Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	Illumina/Solexa, Genome Analyzer II
Secondary Analysis:	CASAVA Software v1.7
Breeder:	Medical College of Wisconsin
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.5.9-r16 and GATK v1.3-14

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.5.9-r16 and GATK v2.3-5

LE/Stm (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLID
Secondary Analysis:	SAP42 (Developed at RNAAS)
Breeder:	Dr. Tadao Serikawa, Kyoto Japan.
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

M520/N (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLID
Secondary Analysis:	SAP42 (Developed at RNAAS)
Breeder:	National Institutes of Health
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

MR/N (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLID
Breeder:	National Institutes of Health
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

SHR/Olalpcv (ICL)

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Sequenced By:	Imperial College London (Dr Timothy Aitman) University of British Columbia (Dr. Steven Jones)
Platform:	Illumina Hi-seq 2000 and GAII
Secondary Analysis:	BWA, GATK
Breeder:	Institute of Physiology, Academy of Sciences of the Czech Republic, Prague
Grant Information:	LSHG-CT-2005-019015, HEALTH-F4-2010-241504

SHR/Olalpcv (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Imperial College London (Dr Timothy Aitman)
Platform:	Illumina
Secondary Analysis:	GATK
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

SHRSP/Gcrc (MDC)

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Sequenced By:	Max Delbruch Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	Illumina/Solexa, Genome Analyzer II
Secondary Analysis:	CASAVA Software v1.7
Breeder:	University of Glasgow, Anna Dominiczak
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.5.9-r16 and GATK v1.3-14
Breeder:	Harlan

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.5.9-r16 and GATK v1.3-14
Grant Information:	R01 HL089930

SS/JrHsdMcwi (MDC)

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Sequenced By:	Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	Illumina/Solexa, Genome Analyzer II
Secondary Analysis:	CASAVA Software v1.7
Breeder:	Medical College of Wisconsin
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

WKY/N (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLID
Secondary Analysis:	SAP42 (Developed at RNAAS)
Breeder:	National Institutes of Health
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

WN/N (KNAW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLID
Secondary Analysis:	SAP42 (Developed at RNAAS)
Breeder:	National Institutes of Health
Grant Information:	EURATRANS (HEALTH-F4-2010-241504)

Additional Information

External Database Links

Nomenclature History

More on LOC685964
	Entrez Gene
	Ensembl Gene
	Genome Browser
	NCBI Map Viewer
	Vista
	Vista + UCSC

RGD Object Information
RGD ID:	1587811
Created:	2006-11-19
Species:	Rattus norvegicus
Last Modified:	2013-05-28
Status:	ACTIVE