Glyatl3 (glycine-N-acyltransferase-like 3) - Rat Genome Database

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Gene: Glyatl3 (glycine-N-acyltransferase-like 3) Rattus norvegicus
Analyze
Symbol: Glyatl3
Name: glycine-N-acyltransferase-like 3
RGD ID: 1587643
Description: Predicted to enable glycine N-acyltransferase activity. Predicted to be located in mitochondrion. Orthologous to human GLYATL3 (glycine-N-acyltransferase like 3); INTERACTS WITH acrylamide; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glycine N-acyltransferase-like protein 3; LOC688448; LOC688536; similar to kidney expressed gene 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8927,474,057 - 27,492,281 (+)NCBIGRCr8
mRatBN7.2919,977,493 - 19,995,723 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl919,977,302 - 19,995,650 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx928,555,452 - 28,565,981 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0933,630,005 - 33,640,537 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0931,937,028 - 31,947,315 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0923,372,614 - 23,390,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl923,379,200 - 23,390,487 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0922,236,745 - 22,248,032 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4916,119,729 - 16,131,491 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera917,661,422 - 17,672,330 (+)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:27016726  


Genomics

Comparative Map Data
Glyatl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8927,474,057 - 27,492,281 (+)NCBIGRCr8
mRatBN7.2919,977,493 - 19,995,723 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl919,977,302 - 19,995,650 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx928,555,452 - 28,565,981 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0933,630,005 - 33,640,537 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0931,937,028 - 31,947,315 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0923,372,614 - 23,390,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl923,379,200 - 23,390,487 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0922,236,745 - 22,248,032 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4916,119,729 - 16,131,491 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera917,661,422 - 17,672,330 (+)NCBICelera
Cytogenetic Map9q13NCBI
GLYATL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38649,499,923 - 49,528,078 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl649,499,923 - 49,528,078 (+)EnsemblGRCh38hg38GRCh38
GRCh37649,467,636 - 49,495,791 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36649,467,671 - 49,495,777 (+)NCBINCBI36Build 36hg18NCBI36
Celera651,023,868 - 51,051,973 (+)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef649,197,157 - 49,225,147 (+)NCBIHuRef
CHM1_1649,470,698 - 49,498,820 (+)NCBICHM1_1
T2T-CHM13v2.0649,342,084 - 49,370,250 (+)NCBIT2T-CHM13v2.0
Glyatl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391741,214,599 - 41,229,469 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1741,215,509 - 41,225,241 (-)EnsemblGRCm39 Ensembl
GRCm381740,904,727 - 40,923,048 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1740,904,618 - 40,914,350 (-)EnsemblGRCm38mm10GRCm38
MGSCv371741,041,690 - 41,051,299 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361740,368,225 - 40,376,239 (-)NCBIMGSCv36mm8
Celera1744,314,932 - 44,324,945 (-)NCBICelera
Cytogenetic Map17B2NCBI
cM Map1719.55NCBI
Glyatl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541033,444,100 - 33,462,285 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541033,444,100 - 33,462,285 (-)NCBIChiLan1.0ChiLan1.0
GLYATL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2563,989,981 - 64,011,474 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1659,854,701 - 59,876,197 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0649,075,808 - 49,097,303 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1650,337,934 - 50,359,318 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl650,337,934 - 50,359,318 (+)Ensemblpanpan1.1panPan2
GLYATL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11217,359,085 - 17,375,833 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1217,362,736 - 17,375,694 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1217,259,077 - 17,275,637 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01217,855,371 - 17,871,923 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1217,858,986 - 17,870,755 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11217,375,110 - 17,391,850 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01217,480,383 - 17,497,143 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01217,610,009 - 17,626,571 (+)NCBIUU_Cfam_GSD_1.0
Glyatl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494652,776,950 - 52,788,712 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647611,172,032 - 11,183,099 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647611,172,032 - 11,183,099 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLYATL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl743,639,946 - 43,659,566 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1743,641,443 - 43,659,754 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2750,130,074 - 50,144,643 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GLYATL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11722,871,047 - 22,894,071 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1722,872,486 - 22,892,476 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604449,485,043 - 49,505,679 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Glyatl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247831,796,386 - 1,813,262 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247831,796,648 - 1,813,268 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Glyatl3
102 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:32
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000074110
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 2 5 4 1 4 12 6 18
Below cutoff 27 25 19 13 19 2 2 39 15 18 2 2

Sequence


RefSeq Acc Id: ENSRNOT00000074110   ⟹   ENSRNOP00000066244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl919,977,302 - 19,995,650 (+)Ensembl
Rnor_6.0 Ensembl923,379,200 - 23,390,487 (+)Ensembl
RefSeq Acc Id: NM_001145062   ⟹   NP_001138534
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8927,474,057 - 27,492,281 (+)NCBI
mRatBN7.2919,977,493 - 19,995,723 (+)NCBI
Rnor_6.0923,379,200 - 23,390,487 (+)NCBI
Rnor_5.0922,236,745 - 22,248,032 (+)NCBI
RGSC_v3.4916,119,729 - 16,131,491 (+)RGD
Celera917,661,422 - 17,672,330 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001138534 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066244
  ENSRNOP00000066244.1
RefSeq Acc Id: NP_001138534   ⟸   NM_001145062
- UniProtKB: D3ZHY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000066244   ⟸   ENSRNOT00000074110
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHY4-F1-model_v2 AlphaFold D3ZHY4 1-290 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1587643 AgrOrtholog
BioCyc Gene G2FUF-28084 BioCyc
Ensembl Genes ENSRNOG00000050990 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000074110 ENTREZGENE
  ENSRNOT00000074110.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.630.30 UniProtKB/TrEMBL
InterPro Acyl_CoA_acyltransferase UniProtKB/TrEMBL
  Glycine_N-acyltransferase UniProtKB/TrEMBL
  Glycine_N-acyltransferase_C UniProtKB/TrEMBL
  Glycine_N-acyltransferase_N UniProtKB/TrEMBL
KEGG Report rno:688536 UniProtKB/TrEMBL
NCBI Gene 688536 ENTREZGENE
PANTHER GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 3 UniProtKB/TrEMBL
  PTHR15298 UniProtKB/TrEMBL
Pfam Gly_acyl_tr_C UniProtKB/TrEMBL
  Gly_acyl_tr_N UniProtKB/TrEMBL
PhenoGen Glyatl3 PhenoGen
RatGTEx ENSRNOG00000050990 RatGTEx
Superfamily-SCOP Acyl_CoA_acyltransferase UniProtKB/TrEMBL
UniProt D3ZHY4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Glyatl3  glycine-N-acyltransferase-like 3  LOC688448  similar to kidney expressed gene 1  Data merged from RGD:1588840 737654 PROVISIONAL
2010-04-23 Glyatl3  glycine-N-acyltransferase-like 3  LOC688536  similar to kidney expressed gene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC688448  similar to kidney expressed gene 1  LOC684248  similar to kidney expressed gene 1  Data merged from RGD:1592699 1643240 APPROVED
2006-11-20 LOC684248  similar to kidney expressed gene 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC688448  similar to kidney expressed gene 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC688536  similar to kidney expressed gene 1      Symbol and Name status set to provisional 70820 PROVISIONAL