C19h19orf67 (similar to human chromosome 19 open reading frame 67) - Rat Genome Database

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Gene: C19h19orf67 (similar to human chromosome 19 open reading frame 67) Rattus norvegicus
Analyze
Symbol: C19h19orf67 (Ensembl: LOC686013)
Name: similar to human chromosome 19 open reading frame 67 (Ensembl:RIKEN cDNA 1700067K01 gene)
RGD ID: 1586683
Description: Predicted to act upstream of or within in utero embryonic development. Orthologous to human C19orf67 (chromosome 19 open reading frame 67); INTERACTS WITH bisphenol A; resveratrol (ortholog); sodium arsenite (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC686013; LOC686013; rCG51246-like; uncharacterized protein LOC686013; UPF0575 protein C19orf67 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81941,051,577 - 41,054,875 (-)NCBIGRCr8
mRatBN7.21924,146,815 - 24,150,983 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,146,815 - 24,150,095 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01925,122,870 - 25,126,960 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1925,123,724 - 25,127,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01936,100,780 - 36,103,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41925,832,898 - 25,835,839 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1923,694,648 - 23,699,266 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:27996060  


Genomics

Comparative Map Data
C19h19orf67
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81941,051,577 - 41,054,875 (-)NCBIGRCr8
mRatBN7.21924,146,815 - 24,150,983 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,146,815 - 24,150,095 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01925,122,870 - 25,126,960 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1925,123,724 - 25,127,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01936,100,780 - 36,103,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41925,832,898 - 25,835,839 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1923,694,648 - 23,699,266 (-)NCBICelera
Cytogenetic Map19q11NCBI
C19orf67
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381914,081,624 - 14,085,783 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1914,081,624 - 14,085,875 (-)EnsemblGRCh38hg38GRCh38
GRCh371914,192,436 - 14,196,595 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,052,952 - 14,057,439 (-)NCBINCBI36Build 36hg18NCBI36
Celera1914,085,754 - 14,090,241 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1913,764,099 - 13,768,262 (-)NCBIHuRef
CHM1_11914,193,014 - 14,197,177 (-)NCBICHM1_1
T2T-CHM13v2.01914,207,916 - 14,212,075 (-)NCBIT2T-CHM13v2.0
1700067K01Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,727,145 - 84,731,399 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl884,728,131 - 84,731,399 (+)EnsemblGRCm39 Ensembl
GRCm38884,000,516 - 84,004,770 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl884,001,502 - 84,004,770 (+)EnsemblGRCm38mm10GRCm38
MGSCv37886,525,605 - 86,528,669 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36886,891,657 - 86,894,875 (+)NCBIMGSCv36mm8
Celera888,295,023 - 88,298,103 (+)NCBICelera
Cytogenetic Map8C2NCBI
cM Map840.24NCBI
CUNH19orf67
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541532,785,649 - 32,788,706 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541532,785,472 - 32,789,328 (-)NCBIChiLan1.0ChiLan1.0
C20H19orf67
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,013,748 - 19,017,951 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,015,415 - 18,020,865 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01913,646,905 - 13,651,425 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11914,374,098 - 14,378,137 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1914,374,098 - 14,378,134 (-)Ensemblpanpan1.1panPan2
C20H19orf67
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12048,431,736 - 48,435,274 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2048,432,244 - 48,435,273 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2048,306,586 - 48,310,955 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02048,949,871 - 48,954,194 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2048,949,670 - 48,952,956 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12048,161,041 - 48,165,383 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02048,587,607 - 48,591,946 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02048,830,424 - 48,834,765 (+)NCBIUU_Cfam_GSD_1.0
CUNH19orf67
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118207,611,022 - 207,614,129 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366592,740,728 - 2,743,490 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366592,740,595 - 2,743,490 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C2H19orf67
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl265,100,755 - 65,104,628 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1265,100,933 - 65,103,997 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2265,374,485 - 65,378,332 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH19orf67
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1612,723,781 - 12,733,587 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl612,723,991 - 12,733,051 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660746,921,343 - 6,925,797 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH19orf67
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249011,310,605 - 1,314,415 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249011,310,671 - 1,314,361 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C19h19orf67
8 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:93
Count of miRNA genes:80
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000007407
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8
Low 3 11 27 11 19 11 8 11 11 11 12 11 8
Below cutoff 16 10 10 10 31 14 18

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000007407   ⟹   ENSRNOP00000007407
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,146,815 - 24,150,095 (-)Ensembl
Rnor_6.0 Ensembl1925,123,724 - 25,127,145 (+)Ensembl
RefSeq Acc Id: NM_001419771   ⟹   NP_001406700
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,051,577 - 41,054,875 (-)NCBI
mRatBN7.21924,146,815 - 24,150,113 (-)NCBI
RefSeq Acc Id: XM_001066168   ⟹   XP_001066168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,051,577 - 41,054,756 (-)NCBI
mRatBN7.21924,146,921 - 24,150,983 (-)NCBI
Rnor_6.01925,122,870 - 25,126,960 (+)NCBI
Rnor_5.01936,100,780 - 36,103,979 (+)NCBI
RGSC_v3.41925,832,898 - 25,835,839 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001406700 (Get FASTA)   NCBI Sequence Viewer  
  XP_001066168 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL92248 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007407
  ENSRNOP00000007407.4
Reference Protein Sequences
RefSeq Acc Id: XP_001066168   ⟸   XM_001066168
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000007407   ⟸   ENSRNOT00000007407
RefSeq Acc Id: NP_001406700   ⟸   NM_001419771
- UniProtKB: D4A283 (UniProtKB/TrEMBL),   A6IYC0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A283-F1-model_v2 AlphaFold D4A283 1-356 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701010
Promoter ID:EPDNEW_R11532
Type:single initiation site
Name:LOC686013_1
Description:hypothetical protein LOC686013
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01925,123,773 - 25,123,833EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586683 AgrOrtholog
BioCyc Gene G2FUF-6041 BioCyc
Ensembl Genes ENSRNOG00000005533 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007407 ENTREZGENE
  ENSRNOT00000007407.5 UniProtKB/TrEMBL
InterPro DUF3314 UniProtKB/TrEMBL
NCBI Gene 686013 ENTREZGENE
PANTHER PTHR36292 UniProtKB/TrEMBL
  UPF0575 PROTEIN C19ORF67 UniProtKB/TrEMBL
Pfam DUF3314 UniProtKB/TrEMBL
PhenoGen C19h19orf67 PhenoGen
RatGTEx ENSRNOG00000005533 RatGTEx
UniProt A6IYC0 ENTREZGENE, UniProtKB/TrEMBL
  D4A283 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C19h19orf67  similar to human chromosome 19 open reading frame 67  LOC686013  hypothetical protein LOC686013  Symbol and Name Changed 1299863 APPROVED
2013-05-24 LOC686013  hypothetical protein LOC686013  LOC100365832  rCG51246-like  Data merged from RGD:2318255 1643240 APPROVED
2010-05-05 LOC100365832  rCG51246-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-01-09 LOC686013  hypothetical protein LOC686013  LOC684880  hypothetical protein LOC684880  Data merged from RGD:1585518 1643240 APPROVED
2006-11-19 LOC686013  hypothetical protein LOC686013      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC684880  hypothetical protein LOC684880      Symbol and Name status set to provisional 70820 PROVISIONAL