Ncr2l1 (natural cytotoxicity triggering receptor 2 like 1) - Rat Genome Database

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Pathways
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Gene: Ncr2l1 (natural cytotoxicity triggering receptor 2 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ncr2l1 (Ensembl: LOC680920)
Name: natural cytotoxicity triggering receptor 2 like 1 (Ensembl:similar to natural cytotoxicity triggering receptor 2)
RGD ID: 1585869
Description:
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC680920; similar to natural cytotoxicity triggering receptor 2; triggering receptor expressed on myeloid cells 1-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8920,341,134 - 20,355,151 (+)NCBIGRCr8
mRatBN7.2912,843,542 - 12,858,881 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl912,843,566 - 12,857,392 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0914,850,763 - 14,864,999 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl914,851,132 - 14,864,680 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0913,773,870 - 13,787,958 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.498,256,595 - 8,271,097 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera910,633,711 - 10,634,723 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell surface  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Variants

.
Variants in Ncr2l1
115 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:72
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000066779
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
1578675Bss17Bone structure and strength QTL 173.8femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)9336865213533896Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 2 1 10 5 2
Below cutoff 1 10 17 12 6 12 4 5 2 12 14 7 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000040323   ⟹   ENSRNOP00000048233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl912,843,566 - 12,857,392 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000066779   ⟹   ENSRNOP00000062495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl912,843,566 - 12,847,830 (+)Ensembl
Rnor_6.0 Ensembl914,851,132 - 14,864,680 (+)Ensembl
RefSeq Acc Id: XM_006244494   ⟹   XP_006244556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,341,134 - 20,355,151 (+)NCBI
mRatBN7.2912,843,542 - 12,858,881 (+)NCBI
Rnor_6.0914,850,763 - 14,864,999 (+)NCBI
Rnor_5.0913,773,870 - 13,787,958 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039084482   ⟹   XP_038940410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,341,134 - 20,355,151 (+)NCBI
mRatBN7.2912,843,542 - 12,858,881 (+)NCBI
Protein Sequences
Protein RefSeqs XP_006244556 (Get FASTA)   NCBI Sequence Viewer  
  XP_038940410 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000048233
  ENSRNOP00000048233.5
  ENSRNOP00000062495.4
Reference Protein Sequences
RefSeq Acc Id: XP_006244556   ⟸   XM_006244494
- Peptide Label: isoform X1
- UniProtKB: F1LTR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000062495   ⟸   ENSRNOT00000066779
RefSeq Acc Id: XP_038940410   ⟸   XM_039084482
- Peptide Label: isoform X2
- UniProtKB: D3ZDX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000048233   ⟸   ENSRNOT00000040323
Protein Domains
Immunoglobulin V-set

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZDX3-F1-model_v2 AlphaFold D3ZDX3 1-132 view protein structure
AF-F1LTR7-F1-model_v2 AlphaFold F1LTR7 1-232 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1585869 AgrOrtholog
BioCyc Gene G2FUF-28293 BioCyc
Ensembl Genes ENSRNOG00000042468 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040323.6 UniProtKB/TrEMBL
  ENSRNOT00000066779.4 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
NCBI Gene 680920 ENTREZGENE
PANTHER CRKD-BINDING PROTEIN-RELATED UniProtKB/TrEMBL
  TREM-LIKE TRANSCRIPT PROTEIN UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PhenoGen Ncr2l1 PhenoGen
RatGTEx ENSRNOG00000042468 RatGTEx
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt D3ZDX3 ENTREZGENE, UniProtKB/TrEMBL
  F1LTR7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Ncr2l1  natural cytotoxicity triggering receptor 2 like 1  LOC680920  similar to natural cytotoxicity triggering receptor 2  Symbol and Name Changed 1299863 APPROVED
2008-01-09 LOC680920  similar to natural cytotoxicity triggering receptor 2  LOC686501  hypothetical protein LOC686501  Data merged from RGD:1596396 1643240 APPROVED
2006-11-20 LOC686501  hypothetical protein LOC686501      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC680920  similar to natural cytotoxicity triggering receptor 2      Symbol and Name status set to provisional 70820 PROVISIONAL