Spin2bl1 (spindlin family member 2B like 1) - Rat Genome Database

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Gene: Spin2bl1 (spindlin family member 2B like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Spin2bl1 (Ensembl: RGD1565862)
Name: spindlin family member 2B like 1 (Ensembl:similar to Spindlin-like protein 2 (SPIN-2))
RGD ID: 1565862
Description: Predicted to be involved in gamete generation; INTERACTS WITH 17beta-estradiol; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC302579; RGD1565862; similar to Spindlin-like protein 2 (SPIN-2); spindlin-2-like; spindlin-2B-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X19,851,615 - 19,880,090 (-)NCBIGRCr8
mRatBN7.2X17,118,840 - 17,133,137 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX17,118,816 - 17,129,381 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X18,080,209 - 18,092,441 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X18,845,475 - 18,850,660 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X27,932,154 - 27,948,738 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX17,209,868 - 17,226,914 (-)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA)
nucleoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Spin2bl1
19 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:126
Count of miRNA genes:103
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000042670
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X162371522646544Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_006227295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001835001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001842678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000045517   ⟹   ENSRNOP00000046674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX17,118,816 - 17,129,381 (-)Ensembl
RefSeq Acc Id: XM_039100266   ⟹   XP_038956194
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,084 (-)NCBI
mRatBN7.2X17,118,840 - 17,133,137 (-)NCBI
RefSeq Acc Id: XM_039100268   ⟹   XP_038956196
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,860,528 (-)NCBI
mRatBN7.2X17,118,840 - 17,133,137 (-)NCBI
RefSeq Acc Id: XM_063280458   ⟹   XP_063136528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
RefSeq Acc Id: XM_063280459   ⟹   XP_063136529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,089 (-)NCBI
RefSeq Acc Id: XM_063280460   ⟹   XP_063136530
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,089 (-)NCBI
RefSeq Acc Id: XM_063280461   ⟹   XP_063136531
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
RefSeq Acc Id: XM_063280462   ⟹   XP_063136532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
RefSeq Acc Id: XM_063280463   ⟹   XP_063136533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
RefSeq Acc Id: XM_063280464   ⟹   XP_063136534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
RefSeq Acc Id: XM_063280465   ⟹   XP_063136535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
RefSeq Acc Id: XM_063280466   ⟹   XP_063136536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
RefSeq Acc Id: XM_063280467   ⟹   XP_063136537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
RefSeq Acc Id: XM_063280468   ⟹   XP_063136538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
RefSeq Acc Id: XM_063280469   ⟹   XP_063136539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
RefSeq Acc Id: XM_063280470   ⟹   XP_063136540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X19,851,615 - 19,880,090 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038956196   ⟸   XM_039100268
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956194   ⟸   XM_039100266
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000046674   ⟸   ENSRNOT00000045517
RefSeq Acc Id: XP_063136531   ⟸   XM_063280461
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136539   ⟸   XM_063280469
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136538   ⟸   XM_063280468
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136537   ⟸   XM_063280467
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136536   ⟸   XM_063280466
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136535   ⟸   XM_063280465
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136534   ⟸   XM_063280464
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136540   ⟸   XM_063280470
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136533   ⟸   XM_063280463
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136532   ⟸   XM_063280462
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136528   ⟸   XM_063280458
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136530   ⟸   XM_063280460
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136529   ⟸   XM_063280459
- UniProtKB: F1LPW6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LPW6-F1-model_v2 AlphaFold F1LPW6 1-236 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565862 AgrOrtholog
BioCyc Gene G2FUF-2850 BioCyc
Ensembl Genes ENSRNOG00000068201 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045517.4 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.70 UniProtKB/TrEMBL
InterPro SPIN/Ssty UniProtKB/TrEMBL
  SPIN/Ssty_sf UniProtKB/TrEMBL
NCBI Gene 302579 ENTREZGENE
PANTHER PTHR10405 UniProtKB/TrEMBL
  PTHR10405:SF13 UniProtKB/TrEMBL
Pfam Spin-Ssty UniProtKB/TrEMBL
PhenoGen Spin2bl1 PhenoGen
RatGTEx ENSRNOG00000068201 RatGTEx
UniProt F1LPW6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Spin2bl1  spindlin family member 2B like 1  RGD1565862  similar to Spindlin-like protein 2 (SPIN-2)  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1565862  similar to Spindlin-like protein 2 (SPIN-2)   RGD1565862_predicted  similar to Spindlin-like protein 2 (SPIN-2) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565862_predicted  similar to Spindlin-like protein 2 (SPIN-2) (predicted)  LOC302579  similar to Spindlin-like protein 2 (SPIN-2)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302579  similar to Spindlin-like protein 2 (SPIN-2)      Symbol and Name status set to provisional 70820 PROVISIONAL