Mageb6 (MAGE family member B6) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Mageb6 (MAGE family member B6) Rattus norvegicus
Analyze
Symbol: Mageb6
Name: MAGE family member B6
RGD ID: 1565662
Description: Orthologous to human MAGEB6 (MAGE family member B6); INTERACTS WITH aflatoxin B1 (ortholog); benzo[a]pyrene (ortholog); CGP 52608 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC302441; Mageb17; melanoma antigen family B, 17; melanoma antigen family B, 6; melanoma-associated antigen B17-like; RGD1565662; similar to Smage-3 protein
RGD Orthologs
Human
Mouse
Bonobo
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X60,468,437 - 60,469,905 (-)NCBIGRCr8
mRatBN7.2X56,493,231 - 56,494,699 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX56,492,713 - 56,494,541 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X60,863,372 - 60,864,521 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX60,863,453 - 60,864,478 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X61,448,940 - 61,450,069 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X79,052,623 - 79,053,729 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX56,983,687 - 56,984,836 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Comparative Map Data
Mageb6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X60,468,437 - 60,469,905 (-)NCBIGRCr8
mRatBN7.2X56,493,231 - 56,494,699 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX56,492,713 - 56,494,541 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X60,863,372 - 60,864,521 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX60,863,453 - 60,864,478 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X61,448,940 - 61,450,069 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X79,052,623 - 79,053,729 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX56,983,687 - 56,984,836 (-)NCBICelera
Cytogenetic MapXq22NCBI
MAGEB6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X26,192,440 - 26,195,646 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX26,192,440 - 26,195,646 (+)EnsemblGRCh38hg38GRCh38
GRCh37X26,210,557 - 26,213,763 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X26,120,478 - 26,123,684 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X25,970,213 - 25,973,420NCBI
CeleraX30,337,984 - 30,341,189 (+)NCBICelera
Cytogenetic MapXp21.3NCBI
HuRefX23,949,213 - 23,952,423 (+)NCBIHuRef
CHM1_1X26,242,215 - 26,245,426 (+)NCBICHM1_1
T2T-CHM13v2.0X25,779,752 - 25,782,962 (+)NCBIT2T-CHM13v2.0
Mageb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X90,375,511 - 90,376,503 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX90,375,296 - 90,376,966 (+)EnsemblGRCm39 Ensembl
GRCm38X91,331,905 - 91,332,897 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX91,331,690 - 91,333,360 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X88,577,244 - 88,578,236 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X87,584,624 - 87,585,616 (+)NCBIMGSCv36mm8
CeleraX58,967,165 - 58,967,572 (+)NCBICelera
Cytogenetic MapXC2NCBI
cM MapX40.35NCBI
MAGEB6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X27,995,598 - 27,998,712 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X27,998,979 - 28,002,093 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X18,795,462 - 18,796,559 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X26,159,664 - 26,160,761 (+)NCBIpanpan1.1PanPan1.1panPan2
LOC100513448
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X22,170,175 - 22,171,346 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X23,753,221 - 23,756,311 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mageb6
1 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

reproductive system
High
Medium
Low 14
Below cutoff 13

Sequence


RefSeq Acc Id: ENSRNOT00000088653   ⟹   ENSRNOP00000070675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX56,492,713 - 56,494,541 (-)Ensembl
Rnor_6.0 EnsemblX60,863,453 - 60,864,478 (-)Ensembl
RefSeq Acc Id: NM_001408843   ⟹   NP_001395772
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X60,468,437 - 60,469,905 (-)NCBI
mRatBN7.2X56,493,231 - 56,494,699 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001395772 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96025 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000070675.2
RefSeq Acc Id: ENSRNOP00000070675   ⟸   ENSRNOT00000088653
RefSeq Acc Id: NP_001395772   ⟸   NM_001408843
- UniProtKB: A6IPY8 (UniProtKB/TrEMBL)
Protein Domains
MAGE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JYJ2-F1-model_v2 AlphaFold A0A0G2JYJ2 1-319 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565662 AgrOrtholog
BioCyc Gene G2FUF-2293 BioCyc
Ensembl Genes ENSRNOG00000055102 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000088653.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
  MHD_dom UniProtKB/TrEMBL
NCBI Gene 302441 ENTREZGENE
PANTHER MAGE FAMILY MEMBER B6B UniProtKB/TrEMBL
  PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
PhenoGen Mageb6 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000055102 RatGTEx
SMART MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
UniProt A0A0G2JYJ2_RAT UniProtKB/TrEMBL
  A6IPY8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-04-19 Mageb6  MAGE family member B6  Mageb6  melanoma antigen family B, 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-05 Mageb6  melanoma antigen family B, 6  Mageb17  melanoma antigen family B, 17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-12 Mageb17  melanoma antigen family B, 17  RGD1565662  similar to Smage-3 protein   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565662  similar to Smage-3 protein   RGD1565662_predicted  similar to Smage-3 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565662_predicted  similar to Smage-3 protein (predicted)  LOC302441  similar to Smage-3 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302441  similar to Smage-3 protein      Symbol and Name status set to provisional 70820 PROVISIONAL