Klhl4 (kelch-like family member 4)

Gene: Klhl4 (kelch-like family member 4) Rattus norvegicus

Analyze

Symbol:

Klhl4

Name:

kelch-like family member 4

RGD ID:

1565441

Description:

Predicted to be located in centriolar satellite. Orthologous to human KLHL4 (kelch like family member 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

kelch-like 4; kelch-like 4 (Drosophila); kelch-like protein 4; LOC317196; RGD1565441; similar to KIAA1687 protein

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KLHL4 (kelch like family member 4)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Klhl4 (kelch-like 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Klhl4 (kelch like family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KLHL4 (kelch like family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KLHL4 (kelch like family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Klhl4 (kelch like family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KLHL4 (kelch like family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KLHL4 (kelch like family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Klhl4 (kelch like family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DDAH2 (DDAH family member 2, ADMA-independent)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	KLHL4 (kelch like family member 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Klhl4 (kelch-like 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	klhl4 (kelch-like family member 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG17754	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	klhl4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	83,626,047 - 83,916,328 (+)	NCBI		GRCr8
mRatBN7.2	X	79,429,193 - 79,719,482 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	79,622,113 - 79,719,480 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	81,310,098 - 81,407,006 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	84,708,360 - 84,805,945 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	82,296,515 - 82,393,646 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	86,125,929 - 86,229,565 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	86,126,157 - 86,229,563 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	86,066,906 - 86,171,225 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	103,218,938 - 103,317,748 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	80,890,575 - 80,987,712 (+)	NCBI		Celera
Cytogenetic Map	X	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

amphibole asbestos (ISO)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

carbamazepine (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

cyclosporin A (ISO)

diazinon (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

fenvalerate (EXP)

folic acid (ISO)

genistein (ISO)

indole-3-methanol (EXP)

levonorgestrel (ISO)

lipopolysaccharide (ISO)

mercury dibromide (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (EXP)

phenylmercury acetate (ISO)

potassium chromate (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sunitinib (ISO)

testosterone undecanoate (ISO)

thalidomide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triclosan (ISO)

valproic acid (ISO)

vitamin E (ISO)

XL147 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

Cellular Component

cellular_component (ND)

centriolar satellite (ISO)

microtubule cytoskeleton (ISO)

Molecular Function

molecular_function (ND)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Klhl4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	83,626,047 - 83,916,328 (+)	NCBI		GRCr8
mRatBN7.2	X	79,429,193 - 79,719,482 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	79,622,113 - 79,719,480 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	81,310,098 - 81,407,006 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	84,708,360 - 84,805,945 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	82,296,515 - 82,393,646 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	86,125,929 - 86,229,565 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	86,126,157 - 86,229,563 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	86,066,906 - 86,171,225 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	103,218,938 - 103,317,748 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	80,890,575 - 80,987,712 (+)	NCBI		Celera
Cytogenetic Map	X	q31	NCBI

KLHL4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	87,517,802 - 87,670,050 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	87,517,409 - 87,670,050 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	86,772,805 - 86,925,050 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	86,659,465 - 86,811,706 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	86,578,961 - 86,730,741	NCBI
Celera	X	87,012,392 - 87,164,729 (+)	NCBI		Celera
Cytogenetic Map	X	q21.31	NCBI
HuRef	X	80,353,756 - 80,506,308 (+)	NCBI		HuRef
CHM1_1	X	86,665,377 - 86,817,732 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	85,944,797 - 86,097,065 (+)	NCBI		T2T-CHM13v2.0

Klhl4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	113,384,030 - 113,470,826 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	113,384,030 - 113,470,526 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	114,474,333 - 114,561,129 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	114,474,333 - 114,560,829 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	111,588,129 - 111,674,307 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	110,591,464 - 110,677,642 (+)	NCBI		MGSCv36	mm8
Celera	X	101,283,043 - 101,355,844 (+)	NCBI		Celera
Cytogenetic Map	X	E1	NCBI
cM Map	X	49.47	NCBI

Klhl4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955525	1,849,413 - 1,965,441 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955525	1,849,428 - 1,963,168 (+)	NCBI	ChiLan1.0	ChiLan1.0

KLHL4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	86,985,286 - 87,136,205 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	86,988,893 - 87,139,812 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	76,575,811 - 76,726,687 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	86,678,423 - 86,828,738 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	86,678,164 - 86,829,346 (+)	Ensembl	panpan1.1		panPan2

KLHL4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	67,949,674 - 68,111,260 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	67,949,034 - 68,109,486 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	58,721,143 - 58,882,528 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	69,291,043 - 69,450,378 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	69,291,089 - 69,448,604 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	66,926,923 - 67,088,348 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	68,569,225 - 68,730,643 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	68,163,017 - 68,324,360 (+)	NCBI		UU_Cfam_GSD_1.0

Klhl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	76,323,006 - 76,422,124 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936499	11,235,788 - 11,334,958 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936499	11,235,844 - 11,335,678 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KLHL4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	70,334,774 - 70,435,109 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	70,334,755 - 70,436,299 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	80,884,832 - 81,030,921 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KLHL4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	76,157,121 - 76,316,371 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	76,157,130 - 76,314,932 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666067	4,434,150 - 4,594,245 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Klhl4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624852	493,040 - 629,663 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624852	493,062 - 629,787 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Klhl4
1443 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	602
Count of miRNA genes:	287
Interacting mature miRNAs:	362
Transcripts:	ENSRNOT00000006992
Prediction methods:	Microtar, Miranda, Pita, Pita,Microtar
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	41304447	112935181	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	65612192	120568734	Rat
724551	Glom1	Glomerulus QTL 1	2.8	0.0004	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	X	75294106	120294106	Rat

Markers in Region

RH144205

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	79,718,870 - 79,719,035 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	86,228,956 - 86,229,120	NCBI	Rnor6.0
Rnor_5.0	X	86,170,616 - 86,170,780	UniSTS	Rnor5.0
RGSC_v3.4	X	103,317,139 - 103,317,303	UniSTS	RGSC3.4
Celera	X	80,987,103 - 80,987,267	UniSTS
RH 3.4 Map	X	749.71	UniSTS
Cytogenetic Map	X	q32	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		10	4	4		4			13	10	11
Low	2	33	43	28	18	28	8	9	61	25	30	11	8
Below cutoff	1		10	9	1	9		1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006257199	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099724	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063280013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000006992 ⟹ ENSRNOP00000006992

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	79,622,113 - 79,719,480 (+)	Ensembl
Rnor_6.0 Ensembl	X	86,126,157 - 86,229,563 (+)	Ensembl

RefSeq Acc Id:

NM_001108244 ⟹ NP_001101714

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	83,819,178 - 83,916,328 (+)	NCBI
mRatBN7.2	X	79,622,324 - 79,719,480 (+)	NCBI
Rnor_6.0	X	86,126,346 - 86,229,565 (+)	NCBI
Rnor_5.0	X	86,066,906 - 86,171,225 (+)	NCBI
RGSC_v3.4	X	103,218,938 - 103,317,748 (+)	RGD
Celera	X	80,890,575 - 80,987,712 (+)	RGD

Sequence:

show sequence

ATGTCAGTGTCCGGCAAGAAAGAGTTTGATGTGAAACAGATCCTGAGGCTGCGCTGGAGATGGT
TTAGTCATCCTTCTCAAGGATCCCCTAACACTGGAAGCTGCCTTCAGCAGGAAGGATATGAGCA
TAGAGGGACCCCGGTGCAGGGCAGGTTGAAGAACCACTCACGGGACAGAAACGGACTGAAGAAA
AGCAATAGTCCTGTCCACCACGATATACTGACGCCAGTGCCAGGACCAGCCCCTACCCATCAAA
GAGTCCTTCAGAATTGGCACCAACAAAACGTGATAGTACATCTTCAAGCAAATGAAGACACTCC
TAAAGCCGTTCCAGAAGGAAATTTGCTCAAAGAAGCTTGTGAGAAGCGCGCACGAGATTTGGAG
ATGATGGGTGATGACAATATAGAAGATTCTAGAGCACGACAATATGCTGAGGAGCCTGAACAAA
TGAATGTCATTTCTGAGGATCACTACCGTTCTCGAAACCATGCGGATTATACGCTCTGTAAAAT
GGAAAGCTATTTAAAAGAGAAAAAACTGTGTGATGTGCTACTTATTGCTGGACCGCTTAAAATC
CCAGCTCACAGATTGGTTCTCAGTGCTGTGTCTGATTATTTTGCTGCAATGTTTACTAATGATG
TGCTAGAAGCCAGACAAGAAGAGGTCAAAATGGAAGGAGTGGATCCAAATGCACTTAATTCTTT
AGTGCAGTATGCTTATACAGGTGTGCTGCAACTGAGAGAAGACACCATTGAAAATTTGCTGTCT
GCAGCTTGTCTCTTACAGCTGACTCAGGTCATTGATGTGTGCTGTAATTTCCTCATAAAGCAGC
TTCATCCTTCAAATTGCCTAGGAATTCGCTCATTCGGAGATGCCCAGGGCTGTATGGAGCTTCA
GAATGTGGCACATAAGTACACCATGGAACATTTCATTGATGTCGTAAAGAACCAAGAATTCCTG
CTGCTTCCAGCTAATGAAATATCAAAACTTCTGTGTAGTGATGACATTAATGTGCCTGATGAAG
AAACAATTTTCCATGCTCTTATGCAGTGGGTAGGACATGATGCTCAAGCTAGGCAACAAGATCT
GGCGAAGCTGCTTTCTTATATCAGACTGCCATTACTGTCGCCTCAGTTGCTTGCAGATCTAGAA
AACAGTTCAATGTTTAGTGGTGATCTGGAATGTCAGAAGCTACTAATGGAAGCTATGAAGTATC
ATCTCTTGCCTGAGAGAAGATCCATGTTGCAAAGCCCTCGTACAAAGCCTAGAAAATCAACTGT
GGGGGCACTTTATGCTGTAGGAGGTATGGATGCTGCTAAAGGTACCACTACAATTGAGAAGTAT
GACCTCAGAACCAACAGTTGGATCCATATTGGCACTATGAGTGGTCGTAGACTTCAGTTTGGAG
TTGCAGTTGTTGATAATAAACTTTATGTTGTGGGAGGAAGAGATGGCTTAAAAACTTTGAATAC
TGTGGAATGTTTCAATCCAGTTACTAAAACCTGGGTTGTGATGCCTCCTATGTCAACACATAGA
CATGGGCTAGGCGTGGCCACACTTGAAGGACCAATGTATGCTGTTGGAGGGCACGATGGCTGGA
GCTATCTAAATACTGTAGAAAGATGGGATCCTGATGGACGTCAGTGGAATTATGTGGCCAGCAT
GTCAACCCCAAGAAGCACAGTTGGAGTTGTTGCATTGAACAATAAATTGTATGCTATTGGTGGG
CGTGATGGAAGTTCCTGCCTCAAGTCGATGGAGTACTTTGACCCACATACTAACAAATGGAGTC
TGTGTGCTCCAATGTCCAAAAGACGTGGGGGTGTAGGAGTAGCAACACATAATGGATATTTGTA
TGTTGTAGGGGGTCATGATGCCCCTGCTCCTAATCATTGCTCCAGACTTTCTGACTGTGTGGAA
AGATATGATCCAAAAAGTGATTCATGGTCAACCGTGGCACCTTTGAGTGTTCCTCGAGATGCTG
TTGCAGTATGCCCCCTTGGAGACAAACTCTATGTGGTTGGCGGATATGACGGTCATACCTATTT
GAACACCGTTGAATCATACGATGCTCAGAAAGATGAATGGAAAGAGGAAGTTCCTGTGAACATT
GGAAGAGCTGGAGCATGTGTTGTTGTTGTGAAGCTACACTGAAATTATCATTTGACAATGCAAT
GAAATGGATTTCAAGAATGAAGATTAAACATGTTCTTTTATGAAGTTCATAAGCAAACTAAATG
TTGTTGTGTCGTTCTCATGTATAGTTGAAACTGTTAACATTCGTAAGGCTGAAAACAAAAATTA
AATGTGGATTACATGTTAGTGTTAAGTGTATGTGCTCAGATTATAGTCTAATGAGAAATCCAAT
ATGCTATGATTTAAGCTCATTACTCTAAAATGTTAACATACCTAATGGATATTTCATAGTGGAC
AATATTTGAAGGTGATGAATACATTAACAATTTTCATGTAAGGATCTGGGAAGTAAAAAAAAAC
ATTCTGTTAAAGGTACTCTACTGTGTGGAATAACTCAATGGAAAAAAGACAGAAGGTTTAGAGC
ATAATGTCTGGTTTTCAAACAATAGCTGACTTTGCTAATAATACCTCACATTTGTCAAGAAGAA
AGGTTTTTCTGTGTCAAAGATGAAAGTGAACATTCGCTGATGTAATTTGCTATACTAATCACAC
CATTTCAAACTTTTCACAAGCCTATTATTTTTAATTTACTATCTGCCAAAATACATGTATAGAT
TTTCTATTTCATGATGTGGTGTATTGGTACATTCATTTGCAGTAAAATATCATAATGTCACATA
TACAATCTTTATTCTGAAACAGTGAGTCACTGAATATTGTATTGATACAAACTGTGACCTAAGA
TTCAGAATGTGAGGGCCTAATTTGTACAGAAATTAATTTTCCCCTTAAATATTTAGTGTGTTCT
CTGGAAACACCTATTAAGTTTAGAAAGTCGATTTAAACAATTCTAAAGATTATAATTGAGAAAT
GTTCCACAATGTTGACACTTGGATACACCAAAATGTTTAATACACACTGTCAATTCTATAATTT
CTATTTACCTACCAATATCTGTGTTTCTTTTAATTTCATAATCATGTTTCTCCAGTAGGAGATG
GTAAGGATAAATGTTCTACAAAACTACACTTTTGAAGAAAAAAAAAGAATATTGAGTCATTTTA
GCTTTTAACTATTATTTTAATTCATTCTACCTAATGATAAAACTAATATGGTAAAATATTGAAA
ACTAACATTTATGGAGTTAACTTTTCAAGTAAATGTTCCATTTTAGAATTTCTATAATATCTTC
TCTTAAATGAACTTTGTTGACTATCAAAAAAAATCCAGAGTTGATGCTTATAATATGTGTTACT
GCTACGTACTAAATTTTTTTTAAATCATATCATAAGTTGCACAAAGATGTTTGTACTTTGACCA
GCTGAATTTAAATAAAATCTTTTCCCTCTGGC

hide sequence

RefSeq Acc Id:

XM_006257199 ⟹ XP_006257261

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	83,818,654 - 83,916,328 (+)	NCBI
mRatBN7.2	X	79,621,805 - 79,719,482 (+)	NCBI
Rnor_6.0	X	86,125,929 - 86,229,565 (+)	NCBI
Rnor_5.0	X	86,066,906 - 86,171,225 (+)	NCBI

Sequence:

show sequence

TTTGCTTTTACTCACATGCCTGAGTTTAAGTGACAGCTATGCATTTTGGCATCAAAGAAGCAGG
GTTAGATATTTACTAGTTCAGGAGTGAGGACTGTGAGTTTGCATATCTAGCAGCTGGAGTGTGT
TTGTGGTAGCTGCTTTCCTGTGCTAAGCTGATTTACTTGTTTAAGGTCTGACCTCATCATCCTG
TCAGTATGGGTTCCCACCTACACTGTTAGCGGCAGCTTTCTGGCTTCAGCTAAGCTGGAAGTAT
TCACAGGCAGAGGGGGAGGGGAGAGAAAGCAAGAAAAACTGCTCGCTCTCTCAGCACTTGTGCT
TTTGTTAGTTCTACACAAGAGGCAGAGAGAAACAAGAGATAACAAAGGCTCCATTTCCTTTCTG
TTAGAGAAGCCTTTTGTCTTTTCTCGGGCAACAATGTCAGTGTCCGGCAAGAAAGAGTTTGATG
TGAAACAGATCCTGAGGCTGCGCTGGAGATGGTTTAGTCATCCTTCTCAAGGATCCCCTAACAC
TGGAAGCTGCCTTCAGCAGGAAGGATATGAGCATAGAGGGACCCCGGTGCAGGGCAGGTTGAAG
AACCACTCACGGGACAGAAACGGACTGAAGAAAAGCAATAGTCCTGTCCACCACGATATACTGA
CGCCAGTGCCAGGACCAGCCCCTACCCATCAAAGAGTCCTTCAGAATTGGCACCAACAAAACGT
GATAGTACATCTTCAAGCAAATGAAGACACTCCTAAAGCCGTTCCAGAAGGAAATTTGCTCAAA
GAAGCTTGTGAGAAGCGCGCACGAGATTTGGAGATGATGGGTGATGACAATATAGAAGATTCTA
GAGCACGACAATATGCTGAGGAGCCTGAACAAATGAATGTCATTTCTGAGGATCACTACCGTTC
TCGAAACCATGCGGATTATACGCTCTGTAAAATGGAAAGCTATTTAAAAGAGAAAAAACTGTGT
GATGTGCTACTTATTGCTGGACCGCTTAAAATCCCAGCTCACAGATTGGTTCTCAGTGCTGTGT
CTGATTATTTTGCTGCAATGTTTACTAATGATGTGCTAGAAGCCAGACAAGAAGAGGTCAAAAT
GGAAGGAGTGGATCCAAATGCACTTAATTCTTTAGTGCAGTATGCTTATACAGGTGTGCTGCAA
CTGAGAGAAGACACCATTGAAAATTTGCTGTCTGCAGCTTGTCTCTTACAGCTGACTCAGGTCA
TTGATGTGTGCTGTAATTTCCTCATAAAGCAGCTTCATCCTTCAAATTGCCTAGGAATTCGCTC
ATTCGGAGATGCCCAGGGCTGTATGGAGCTTCAGAATGTGGCACATAAGTACACCATGGAACAT
TTCATTGATGTCGTAAAGAACCAAGAATTCCTGCTGCTTCCAGCTAATGAAATATCAAAACTTC
TGTGTAGTGATGACATTAATGTGCCTGATGAAGAAACAATTTTCCATGCTCTTATGCAGTGGGT
AGGACATGATGCTCAAGCTAGGCAACAAGATCTGGCGAAGCTGCTTTCTTATATCAGACTGCCA
TTACTGTCGCCTCAGTTGCTTGCAGATCTAGAAAACAGTTCAATGTTTAGTGGTGATCTGGAAT
GTCAGAAGCTACTAATGGAAGCTATGAAGTATCATCTCTTGCCTGAGAGAAGATCCATGTTGCA
AAGCCCTCGTACAAAGCCTAGAAAATCAACTGTGGGGGCACTTTATGCTGTAGGAGGTACCACT
ACAATTGAGAAGTATGACCTCAGAACCAACAGTTGGATCCATATTGGCACTATGAGTGGTCGTA
GACTTCAGTTTGGAGTTGCAGTTGTTGATAATAAACTTTATGTTGTGGGAGGAAGAGATGGCTT
AAAAACTTTGAATACTGTGGAATGTTTCAATCCAGTTACTAAAACCTGGGTTGTGATGCCTCCT
ATGTCAACACATAGACATGGGCTAGGCGTGGCCACACTTGAAGGACCAATGTATGCTGTTGGAG
GGCACGATGGCTGGAGCTATCTAAATACTGTAGAAAGATGGGATCCTGATGGACGTCAGTGGAA
TTATGTGGCCAGCATGTCAACCCCAAGAAGCACAGTTGGAGTTGTTGCATTGAACAATAAATTG
TATGCTATTGGTGGGCGTGATGGAAGTTCCTGCCTCAAGTCGATGGAGTACTTTGACCCACATA
CTAACAAATGGAGTCTGTGTGCTCCAATGTCCAAAAGACGTGGGGGTGTAGGAGTAGCAACACA
TAATGGATATTTGTATGTTGTAGGGGGTCATGATGCCCCTGCTCCTAATCATTGCTCCAGACTT
TCTGACTGTGTGGAAAGATATGATCCAAAAAGTGATTCATGGTCAACCGTGGCACCTTTGAGTG
TTCCTCGAGATGCTGTTGCAGTATGCCCCCTTGGAGACAAACTCTATGTGGTTGGCGGATATGA
CGGTCATACCTATTTGAACACCGTTGAATCATACGATGCTCAGAAAGATGAATGGAAAGAGGAA
GTTCCTGTGAACATTGGAAGAGCTGGAGCATGTGTTGTTGTTGTGAAGCTACACTGAAATTATC
ATTTGACAATGCAATGAAATGGATTTCAAGAATGAAGATTAAACATGTTCTTTTATGAAGTTCA
TAAGCAAACTAAATGTTGTTGTGTCGTTCTCATGTATAGTTGAAACTGTTAACATTCGTAAGGC
TGAAAACAAAAATTAAATGTGGATTACATGTTAGTGTTAAGTGTATGTGCTCAGATTATAGTCT
AATGAGAAATCCAATATGCTATGATTTAAGCTCATTACTCTAAAATGTTAACATACCTAATGGA
TATTTCATAGTGGACAATATTTGAAGGTGATGAATACATTAACAATTTTCATGTAAGGATCTGG
GAAGTAAAAAAAAACATTCTGTTAAAGGTACTCTACTGTGTGGAATAACTCAATGGAAAAAAGA
CAGAAGGTTTAGAGCATAATGTCTGGTTTTCAAACAATAGCTGACTTTGCTAATAATACCTCAC
ATTTGTCAAGAAGAAAGGTTTTTCTGTGTCAAAGATGAAAGTGAACATTCGCTGATGTAATTTG
CTATACTAATCACACCATTTCAAACTTTTCACAAGCCTATTATTTTTAATTTACTATCTGCCAA
AATACATGTATAGATTTTCTATTTCATGATGTGGTGTATTGGTACATTCATTTGCAGTAAAATA
TCATAATGTCACATATACAATCTTTATTCTGAAACAGTGAGTCACTGAATATTGTATTGATACA
AACTGTGACCTAAGATTCAGAATGTGAGGGCCTAATTTGTACAGAAATTAATTTTCCCCTTAAA
TATTTAGTGTGTTCTCTGGAAACACCTATTAAGTTTAGAAAGTCGATTTAAACAATTCTAAAGA
TTATAATTGAGAAATGTTCCACAATGTTGACACTTGGATACACCAAAATGTTTAATACACACTG
TCAATTCTATAATTTCTATTTACCTACCAATATCTGTGTTTCTTTTAATTTCATAATCATGTTT
CTCCAGTAGGAGATGGTAAGGATAAATGTTCTACAAAACTACACTTTTGAAGAAAAAAAAAGAA
TATTGAGTCATTTTAGCTTTTAACTATTATTTTAATTCATTCTACCTAATGATAAAACTAATAT
GGTAAAATATTGAAAACTAACATTTATGGAGTTAACTTTTCAAGTAAATGTTCCATTTTAGAAT
TTCTATAATATCTTCTCTTAAATGAACTTTGTTGACTATCAAAAAAAATCCAGAGTTGATGCTT
ATAATATGTGTTACTGCTACGTACTAAATTTTTTTTAAATCATATCATAAGTTGCACAAAGATG
TTTGTACTTTGACCAGCTGAATTTAAATAAAATCTTTTCCCTCTGGC

hide sequence

RefSeq Acc Id:

XM_039099723 ⟹ XP_038955651

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	83,626,047 - 83,916,328 (+)	NCBI
mRatBN7.2	X	79,429,193 - 79,719,482 (+)	NCBI

RefSeq Acc Id:

XM_039099724 ⟹ XP_038955652

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	83,819,486 - 83,916,328 (+)	NCBI
mRatBN7.2	X	79,622,633 - 79,719,482 (+)	NCBI

RefSeq Acc Id:

XM_063280013 ⟹ XP_063136083

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	83,626,047 - 83,916,328 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101714	(Get FASTA)	NCBI Sequence Viewer
	XP_006257261	(Get FASTA)	NCBI Sequence Viewer
	XP_038955651	(Get FASTA)	NCBI Sequence Viewer
	XP_038955652	(Get FASTA)	NCBI Sequence Viewer
	XP_063136083	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM07070	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006992
	ENSRNOP00000006992.7

RefSeq Acc Id:

NP_001101714 ⟸ NM_001108244

- UniProtKB:

D3ZHI3 (UniProtKB/TrEMBL), A6IVB0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSVSGKKEFDVKQILRLRWRWFSHPSQGSPNTGSCLQQEGYEHRGTPVQGRLKNHSRDRNGLKK
SNSPVHHDILTPVPGPAPTHQRVLQNWHQQNVIVHLQANEDTPKAVPEGNLLKEACEKRARDLE
MMGDDNIEDSRARQYAEEPEQMNVISEDHYRSRNHADYTLCKMESYLKEKKLCDVLLIAGPLKI
PAHRLVLSAVSDYFAAMFTNDVLEARQEEVKMEGVDPNALNSLVQYAYTGVLQLREDTIENLLS
AACLLQLTQVIDVCCNFLIKQLHPSNCLGIRSFGDAQGCMELQNVAHKYTMEHFIDVVKNQEFL
LLPANEISKLLCSDDINVPDEETIFHALMQWVGHDAQARQQDLAKLLSYIRLPLLSPQLLADLE
NSSMFSGDLECQKLLMEAMKYHLLPERRSMLQSPRTKPRKSTVGALYAVGGMDAAKGTTTIEKY
DLRTNSWIHIGTMSGRRLQFGVAVVDNKLYVVGGRDGLKTLNTVECFNPVTKTWVVMPPMSTHR
HGLGVATLEGPMYAVGGHDGWSYLNTVERWDPDGRQWNYVASMSTPRSTVGVVALNNKLYAIGG
RDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATHNGYLYVVGGHDAPAPNHCSRLSDCVE
RYDPKSDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQKDEWKEEVPVNI
GRAGACVVVVKLH

hide sequence

RefSeq Acc Id:	XP_006257261 ⟸ XM_006257199
- Peptide Label:	isoform X1
- UniProtKB:	D3ZHI3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSVSGKKEFDVKQILRLRWRWFSHPSQGSPNTGSCLQQEGYEHRGTPVQGRLKNHSRDRNGLKK SNSPVHHDILTPVPGPAPTHQRVLQNWHQQNVIVHLQANEDTPKAVPEGNLLKEACEKRARDLE MMGDDNIEDSRARQYAEEPEQMNVISEDHYRSRNHADYTLCKMESYLKEKKLCDVLLIAGPLKI PAHRLVLSAVSDYFAAMFTNDVLEARQEEVKMEGVDPNALNSLVQYAYTGVLQLREDTIENLLS AACLLQLTQVIDVCCNFLIKQLHPSNCLGIRSFGDAQGCMELQNVAHKYTMEHFIDVVKNQEFL LLPANEISKLLCSDDINVPDEETIFHALMQWVGHDAQARQQDLAKLLSYIRLPLLSPQLLADLE NSSMFSGDLECQKLLMEAMKYHLLPERRSMLQSPRTKPRKSTVGALYAVGGTTTIEKYDLRTNS WIHIGTMSGRRLQFGVAVVDNKLYVVGGRDGLKTLNTVECFNPVTKTWVVMPPMSTHRHGLGVA TLEGPMYAVGGHDGWSYLNTVERWDPDGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSC LKSMEYFDPHTNKWSLCAPMSKRRGGVGVATHNGYLYVVGGHDAPAPNHCSRLSDCVERYDPKS DSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQKDEWKEEVPVNIGRAGAC VVVVKLH hide sequence

RefSeq Acc Id:

ENSRNOP00000006992 ⟸ ENSRNOT00000006992

RefSeq Acc Id:	XP_038955651 ⟸ XM_039099723
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038955652 ⟸ XM_039099724
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063136083 ⟸ XM_063280013
- Peptide Label:	isoform X3

Protein Domains

BTB

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZHI3-F1-model_v2	AlphaFold	D3ZHI3	1-711	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565441	AgrOrtholog
BioCyc Gene	G2FUF-1810	BioCyc
Ensembl Genes	ENSRNOG00000005215	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006992	ENTREZGENE
	ENSRNOT00000006992.7	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.420	UniProtKB/TrEMBL
	2.120.10.80	UniProtKB/TrEMBL
InterPro	BACK	UniProtKB/TrEMBL
	BTB/POZ-like	UniProtKB/TrEMBL
	BTB/POZ_fold	UniProtKB/TrEMBL
	Kelch-typ_b-propeller	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
KEGG Report	rno:317196	UniProtKB/TrEMBL
NCBI Gene	317196	ENTREZGENE
PANTHER	KELCH-LIKE PROTEIN DIABLO	UniProtKB/TrEMBL
	LD33804P	UniProtKB/TrEMBL
Pfam	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
PhenoGen	Klhl4	PhenoGen
PRINTS	KELCHREPEAT	UniProtKB/TrEMBL
PROSITE	BTB	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000005215	RatGTEx
SMART	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch	UniProtKB/TrEMBL
Superfamily-SCOP	BTB/POZ_fold	UniProtKB/TrEMBL
	SSF117281	UniProtKB/TrEMBL
UniProt	A6IVB0	ENTREZGENE, UniProtKB/TrEMBL
	D3ZHI3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-02-06	Klhl4	kelch-like family member 4	Klhl4	kelch-like 4 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Klhl4	kelch-like 4 (Drosophila)	RGD1565441_predicted	similar to KIAA1687 protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1565441_predicted	similar to KIAA1687 protein (predicted)	LOC317196	similar to KIAA1687 protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC317196	similar to KIAA1687 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar