Vom2r69 (vomeronasal 2 receptor, 69) - Rat Genome Database

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Gene: Vom2r69 (vomeronasal 2 receptor, 69) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r69
Name: vomeronasal 2 receptor, 69
RGD ID: 1564750
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane; INTERACTS WITH bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC289433; RGD1564750; similar to putative pheromone receptor ; vomeronasal 2 receptor 69
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814543,239 - 556,759 (-)NCBIGRCr8
mRatBN7.214528,257 - 541,777 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14528,236 - 541,777 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0141,007,495 - 1,020,982 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl141,007,495 - 1,020,982 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0141,006,116 - 1,019,603 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414724,637 - 738,171 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera14226,231 - 239,642 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17382427  


Genomics

Variants

.
Variants in Vom2r69
70 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:6
Count of miRNA genes:6
Interacting mature miRNAs:6
Transcripts:ENSRNOT00000039900
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

reproductive system
High
Medium
Low
Below cutoff 2

Sequence


RefSeq Acc Id: ENSRNOT00000039900   ⟹   ENSRNOP00000044230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl14528,236 - 541,777 (-)Ensembl
Rnor_6.0 Ensembl141,007,495 - 1,020,982 (+)Ensembl
RefSeq Acc Id: NM_001099468   ⟹   NP_001092938
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814543,239 - 556,759 (-)NCBI
mRatBN7.214528,257 - 541,777 (-)NCBI
Rnor_6.0141,007,495 - 1,020,982 (+)NCBI
Rnor_5.0141,006,116 - 1,019,603 (+)NCBI
RGSC_v3.414724,637 - 738,171 (-)RGD
Celera14226,231 - 239,642 (+)RGD
Sequence:
RefSeq Acc Id: XM_017599091   ⟹   XP_017454580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814543,239 - 556,759 (-)NCBI
mRatBN7.214528,257 - 541,777 (-)NCBI
Rnor_6.0141,007,495 - 1,020,982 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599092   ⟹   XP_017454581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814543,239 - 556,759 (-)NCBI
mRatBN7.214528,257 - 541,777 (-)NCBI
Rnor_6.0141,007,495 - 1,020,982 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599093   ⟹   XP_017454582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814543,239 - 556,759 (-)NCBI
mRatBN7.214528,257 - 541,777 (-)NCBI
Rnor_6.0141,007,495 - 1,020,982 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599094   ⟹   XP_017454583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814543,239 - 556,759 (-)NCBI
mRatBN7.214528,257 - 541,777 (-)NCBI
Rnor_6.0141,007,495 - 1,020,982 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091652   ⟹   XP_038947580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr814543,239 - 556,759 (-)NCBI
mRatBN7.214528,257 - 541,777 (-)NCBI
RefSeq Acc Id: NP_001092938   ⟸   NM_001099468
- Peptide Label: precursor
- UniProtKB: D3ZXT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454583   ⟸   XM_017599094
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017454581   ⟸   XM_017599092
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017454582   ⟸   XM_017599093
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017454580   ⟸   XM_017599091
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000044230   ⟸   ENSRNOT00000039900
RefSeq Acc Id: XP_038947580   ⟸   XM_039091652
- Peptide Label: isoform X5
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZXT3-F1-model_v2 AlphaFold D3ZXT3 1-849 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564750 AgrOrtholog
BioCyc Gene G2FUF-16705 BioCyc
Ensembl Genes ENSRNOG00000040210 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039900 ENTREZGENE
  ENSRNOT00000039900.4 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
KEGG Report rno:289433 UniProtKB/TrEMBL
NCBI Gene 289433 ENTREZGENE
PANTHER PTHR24061 UniProtKB/TrEMBL
  VOMERONASAL 2, RECEPTOR 10-RELATED UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vom2r69 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000040210 RatGTEx
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt D3ZXT3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-07-23 Vom2r69  vomeronasal 2 receptor, 69  RGD1564750  similar to putative pheromone receptor   Symbol and Name updated 1299863 APPROVED
2008-04-30 RGD1564750  similar to putative pheromone receptor   RGD1564750_predicted  similar to putative pheromone receptor (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564750_predicted  similar to putative pheromone receptor (predicted)  LOC289433  similar to putative pheromone receptor  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC289433  similar to putative pheromone receptor      Symbol and Name status set to provisional 70820 PROVISIONAL