Mageb7 (MAGE family member B7) - Rat Genome Database

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Gene: Mageb7 (MAGE family member B7) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Mageb7
Name: MAGE family member B7
RGD ID: 1563904
Description: INVOLVED IN negative regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleus (inferred); INTERACTS WITH manganese(II) chloride; trichloroethene
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC503442; LOC503442; melanoma antigen, family B, 7; RGD1563904; similar to melanoma antigen family B, 4
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X54,916,581 - 54,919,884 (-)NCBIGRCr8
mRatBN7.2X50,965,892 - 50,969,116 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX50,966,208 - 50,967,245 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX52,295,899 - 52,296,936 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X55,796,334 - 55,797,371 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X53,427,297 - 53,428,334 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X54,938,470 - 54,941,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX54,938,845 - 54,939,919 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X55,142,111 - 55,145,020 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X73,217,286 - 73,218,323 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX51,498,715 - 51,499,752 (-)NCBICelera
Cytogenetic MapXq21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Mageb7
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:31
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000065450
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

integumental system musculoskeletal system reproductive system appendage
High
Medium 4
Low 19
Below cutoff 1 2 9 1

Sequence


RefSeq Acc Id: ENSRNOT00000065450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX50,966,208 - 50,967,245 (-)Ensembl
Rnor_6.0 EnsemblX54,938,845 - 54,939,919 (-)Ensembl
RefSeq Acc Id: NM_001109367   ⟹   NP_001102837
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X54,916,661 - 54,919,884 (-)NCBI
mRatBN7.2X50,965,892 - 50,969,116 (-)NCBI
Rnor_6.0X54,938,852 - 54,939,889 (-)NCBI
Rnor_5.0X55,142,111 - 55,145,020 (-)NCBI
RGSC_v3.4X73,217,286 - 73,218,323 (-)RGD
CeleraX51,498,715 - 51,499,752 (-)RGD
Sequence:
RefSeq Acc Id: XM_063280264   ⟹   XP_063136334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X54,916,581 - 54,919,645 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001102837 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136334 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96040 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000083438
  ENSRNOP00000083438.1
RefSeq Acc Id: NP_001102837   ⟸   NM_001109367
- UniProtKB: A0A8I5ZWY3 (UniProtKB/TrEMBL),   A6IPX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_063136334   ⟸   XM_063280264
- Peptide Label: isoform X1
Protein Domains
MAGE

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-2333 BioCyc
Ensembl Genes ENSRNOG00000042751 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000065450 ENTREZGENE
  ENSRNOT00000065450.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
  MHD_dom UniProtKB/TrEMBL
KEGG Report rno:503442 UniProtKB/TrEMBL
NCBI Gene 503442 ENTREZGENE
PANTHER MELANOMA-ASSOCIATED ANTIGEN B4 UniProtKB/TrEMBL
  PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
PhenoGen Mageb7 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000042751 RatGTEx
SMART MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
UniProt A0A8I5ZWY3 ENTREZGENE, UniProtKB/TrEMBL
  A6IPX3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-18 Mageb7  MAGE family member B7  Mageb7  melanoma antigen, family B, 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-05-27 Mageb7  melanoma antigen, family B, 7  RGD1563904  similar to melanoma antigen family B, 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1563904  similar to melanoma antigen family B, 4   RGD1563904_predicted  similar to melanoma antigen family B, 4 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563904_predicted  similar to melanoma antigen family B, 4 (predicted)  LOC503442  similar to melanoma antigen family B, 4  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC503442  similar to melanoma antigen family B, 4      Symbol and Name status set to provisional 70820 PROVISIONAL