Plac1 (placenta enriched 1) - Rat Genome Database

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Gene: Plac1 (placenta enriched 1) Rattus norvegicus
Analyze
Symbol: Plac1
Name: placenta enriched 1
RGD ID: 1563777
Description: Predicted to be involved in placenta development. Predicted to act upstream of or within spongiotrophoblast layer developmental growth. Predicted to be located in extracellular region. Orthologous to human PLAC1 (placenta enriched 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC102550080; placenta-specific 1; placenta-specific protein 1; placenta-specific protein 1-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X137,740,896 - 137,874,688 (-)NCBIGRCr8
mRatBN7.2X132,821,347 - 132,955,143 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX132,821,347 - 132,985,668 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX134,981,404 - 135,022,313 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X138,564,253 - 138,605,155 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X136,129,952 - 136,170,854 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,931,450 - 158,133,506 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX158,053,164 - 158,133,504 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 EnsemblX158,569,056 - 158,569,577 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X152,508,501 - 152,758,813 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X140,014,910 - 140,055,813 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic MapXq36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10995572   PMID:15489334   PMID:22729990  


Genomics

Comparative Map Data
Plac1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X137,740,896 - 137,874,688 (-)NCBIGRCr8
mRatBN7.2X132,821,347 - 132,955,143 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX132,821,347 - 132,985,668 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX134,981,404 - 135,022,313 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X138,564,253 - 138,605,155 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X136,129,952 - 136,170,854 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,931,450 - 158,133,506 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX158,053,164 - 158,133,504 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 EnsemblX158,569,056 - 158,569,577 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X152,508,501 - 152,758,813 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X140,014,910 - 140,055,813 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic MapXq36NCBI
PLAC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X134,565,838 - 134,764,322 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX134,565,838 - 134,764,322 (-)EnsemblGRCh38hg38GRCh38
GRCh37X133,699,868 - 133,898,352 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X133,527,539 - 133,620,179 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X133,425,392 - 133,518,033NCBI
CeleraX134,086,692 - 134,179,370 (-)NCBICelera
Cytogenetic MapXq26.3NCBI
HuRefX123,098,723 - 123,191,076 (-)NCBIHuRef
CHM1_1X133,611,604 - 133,704,211 (-)NCBICHM1_1
T2T-CHM13v2.0X132,891,012 - 133,089,435 (-)NCBIT2T-CHM13v2.0
Plac1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X52,158,870 - 52,328,969 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX52,158,872 - 52,328,988 (-)EnsemblGRCm39 Ensembl
GRCm38X53,069,993 - 53,240,110 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX53,069,995 - 53,240,111 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X50,423,179 - 50,467,582 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X49,314,629 - 49,359,032 (-)NCBIMGSCv36mm8
CeleraX40,495,994 - 40,539,998 (-)NCBICelera
Cytogenetic MapXA5NCBI
cM MapX29.31NCBI
Plac1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955473264,265 - 415,616 (+)NCBIChiLan1.0ChiLan1.0
PLAC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X134,001,183 - 134,169,153 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X134,004,781 - 134,005,817 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X123,715,148 - 123,913,821 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X134,013,624 - 134,159,805 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX134,013,830 - 134,014,468 (-)Ensemblpanpan1.1panPan2
PLAC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X105,200,725 - 105,390,714 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX91,311,411 - 91,356,422 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X107,052,170 - 107,053,059 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX107,052,230 - 107,052,868 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X104,473,935 - 104,518,964 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X106,339,901 - 106,384,891 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X106,131,606 - 106,176,593 (-)NCBIUU_Cfam_GSD_1.0
Plac1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X103,353,828 - 103,399,620 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936691602,707 - 603,342 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLAC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX110,403,437 - 110,539,258 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X110,403,257 - 110,592,117 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PLAC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X109,735,568 - 109,934,564 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX109,736,338 - 109,736,976 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606547,340,699 - 47,540,364 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plac1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479714,259,180 - 14,435,455 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plac1
50 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:46
Count of miRNA genes:41
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000003235
Prediction methods:Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 18 10 8 8 16 35
Below cutoff 8 16 10 2 10 1 3 33 5 3 6 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003235   ⟹   ENSRNOP00000003235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX132,821,350 - 132,985,668 (-)Ensembl
Rnor_6.0 EnsemblX158,053,164 - 158,133,504 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000074170   ⟹   ENSRNOP00000064922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX132,821,430 - 132,955,076 (-)Ensembl
Rnor_6.0 EnsemblX158,569,056 - 158,569,577 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094212   ⟹   ENSRNOP00000079856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX132,821,349 - 132,985,652 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105041   ⟹   ENSRNOP00000082384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX132,821,349 - 132,863,793 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110634   ⟹   ENSRNOP00000080103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX132,821,347 - 132,858,152 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114351   ⟹   ENSRNOP00000093046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX132,821,348 - 132,862,996 (-)Ensembl
RefSeq Acc Id: NM_001024894   ⟹   NP_001020065
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,740,896 - 137,781,800 (-)NCBI
mRatBN7.2X132,821,347 - 132,862,249 (-)NCBI
Rnor_6.0X158,059,897 - 158,133,506 (+)NCBI
Rnor_5.0X152,508,501 - 152,758,813 (+)NCBI
RGSC_v3.4X140,014,910 - 140,055,813 (-)RGD
Sequence:
RefSeq Acc Id: XM_017602056   ⟹   XP_017457545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,740,896 - 137,874,688 (-)NCBI
mRatBN7.2X132,821,347 - 132,955,143 (-)NCBI
Rnor_6.0X157,931,450 - 158,133,506 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001020065   ⟸   NM_001024894
- Peptide Label: precursor
- UniProtKB: Q4V7E2 (UniProtKB/Swiss-Prot),   A6KUJ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457545   ⟸   XM_017602056
- Peptide Label: isoform X1
- UniProtKB: Q4V7E2 (UniProtKB/Swiss-Prot),   A6KUJ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003235   ⟸   ENSRNOT00000003235
RefSeq Acc Id: ENSRNOP00000064922   ⟸   ENSRNOT00000074170
RefSeq Acc Id: ENSRNOP00000080103   ⟸   ENSRNOT00000110634
RefSeq Acc Id: ENSRNOP00000082384   ⟸   ENSRNOT00000105041
RefSeq Acc Id: ENSRNOP00000079856   ⟸   ENSRNOT00000094212
RefSeq Acc Id: ENSRNOP00000093046   ⟸   ENSRNOT00000114351
Protein Domains
ZP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4V7E2-F1-model_v2 AlphaFold Q4V7E2 1-173 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563777 AgrOrtholog
BioCyc Gene G2FUF-979 BioCyc
Ensembl Genes ENSRNOG00000002379 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00000047095 Ensembl
  ENSRNOG00055027023 UniProtKB/Swiss-Prot
  ENSRNOG00060024165 UniProtKB/Swiss-Prot
  ENSRNOG00065029049 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003235.8 UniProtKB/Swiss-Prot
  ENSRNOT00000074170.2 UniProtKB/Swiss-Prot
  ENSRNOT00000094212.1 UniProtKB/Swiss-Prot
  ENSRNOT00000105041.1 UniProtKB/TrEMBL
  ENSRNOT00000110634.1 UniProtKB/TrEMBL
  ENSRNOT00000114351 ENTREZGENE
  ENSRNOT00000114351.1 UniProtKB/Swiss-Prot
  ENSRNOT00055046662 UniProtKB/Swiss-Prot
  ENSRNOT00055046668 UniProtKB/Swiss-Prot
  ENSRNOT00060041828 UniProtKB/Swiss-Prot
  ENSRNOT00060041840 UniProtKB/Swiss-Prot
  ENSRNOT00065050193 UniProtKB/Swiss-Prot
  ENSRNOT00065050232 UniProtKB/Swiss-Prot
Gene3D-CATH Zona pellucida, ZP-N domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7443160 IMAGE-MGC_LOAD
InterPro PLAC1_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:317316 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:116112 IMAGE-MGC_LOAD
NCBI Gene 317316 ENTREZGENE
PANTHER PTHR14380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR14380:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Zona_pellucida UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Plac1 PhenoGen
RatGTEx ENSRNOG00000002379 RatGTEx
  ENSRNOG00000047095 RatGTEx
  ENSRNOG00055027023 RatGTEx
  ENSRNOG00060024165 RatGTEx
  ENSRNOG00065029049 RatGTEx
UniProt A0A8I5ZPJ6_RAT UniProtKB/TrEMBL
  A0A8I5ZU17_RAT UniProtKB/TrEMBL
  A6KUJ7 ENTREZGENE, UniProtKB/TrEMBL
  PLAC1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Plac1  placenta enriched 1  LOC102550080  placenta-specific protein 1-like  Data merged from RGD:7688773 737654 PROVISIONAL
2019-08-09 Plac1  placenta enriched 1  Plac1  placenta-specific 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102550080  placenta-specific protein 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-02-09 Plac1  placenta-specific 1      Symbol and Name status set to provisional 70820 PROVISIONAL