Ttll5 (tubulin tyrosine ligase like 5) - Rat Genome Database

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Gene: Ttll5 (tubulin tyrosine ligase like 5) Rattus norvegicus
Analyze
Symbol: Ttll5
Name: tubulin tyrosine ligase like 5
RGD ID: 1563583
Description: Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to act upstream of or within fertilization; retina development in camera-type eye; and sperm axoneme assembly. Predicted to be located in several cellular components, including 9+0 non-motile cilium; cytosol; and microtubule organizing center. Predicted to be active in cilium. Human ortholog(s) of this gene implicated in cone-rod dystrophy 19. Orthologous to human TTLL5 (tubulin tyrosine ligase like 5); INTERACTS WITH Cuprizon; endosulfan; methoxychlor.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC299208; RGD1563583; similar to mKIAA0998 protein; tubulin polyglutamylase TTLL5; tubulin tyrosine ligase-like family, member 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86111,214,048 - 111,431,892 (+)NCBIGRCr8
mRatBN7.26105,483,091 - 105,700,920 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6105,483,191 - 105,700,934 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.06109,693,915 - 109,910,479 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6109,710,781 - 109,879,607 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06119,000,540 - 119,218,774 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46109,947,608 - 110,142,062 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6103,309,943 - 103,527,509 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17499049   PMID:21399614   PMID:23558686   PMID:24791901   PMID:28173158  


Genomics

Comparative Map Data
Ttll5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86111,214,048 - 111,431,892 (+)NCBIGRCr8
mRatBN7.26105,483,091 - 105,700,920 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6105,483,191 - 105,700,934 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.06109,693,915 - 109,910,479 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6109,710,781 - 109,879,607 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06119,000,540 - 119,218,774 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46109,947,608 - 110,142,062 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6103,309,943 - 103,527,509 (+)NCBICelera
Cytogenetic Map6q31NCBI
TTLL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381475,661,246 - 75,955,079 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1475,633,625 - 75,955,079 (+)EnsemblGRCh38hg38GRCh38
GRCh371476,127,589 - 76,421,422 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361475,197,374 - 75,491,175 (+)NCBINCBI36Build 36hg18NCBI36
Build 341475,197,373 - 75,491,174NCBI
Celera1456,165,656 - 56,459,559 (+)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1456,295,510 - 56,590,082 (+)NCBIHuRef
CHM1_11476,065,318 - 76,359,216 (+)NCBICHM1_1
T2T-CHM13v2.01469,870,350 - 70,164,265 (+)NCBIT2T-CHM13v2.0
Ttll5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391285,871,417 - 86,100,534 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1285,871,433 - 86,108,667 (+)EnsemblGRCm39 Ensembl
GRCm381285,824,693 - 86,053,760 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1285,824,659 - 86,061,893 (+)EnsemblGRCm38mm10GRCm38
MGSCv371287,165,900 - 87,394,710 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361286,713,813 - 86,943,005 (+)NCBIMGSCv36mm8
Celera1287,285,084 - 87,513,908 (+)NCBICelera
Cytogenetic Map12D2NCBI
cM Map1239.81NCBI
Ttll5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955612109,743 - 353,918 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955612109,742 - 351,255 (+)NCBIChiLan1.0ChiLan1.0
TTLL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21576,746,669 - 77,044,102 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11475,963,250 - 76,261,730 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01456,216,214 - 56,513,718 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11475,058,897 - 75,356,494 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1475,058,897 - 75,356,494 (+)Ensemblpanpan1.1panPan2
TTLL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1848,651,766 - 48,920,733 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl848,651,814 - 48,920,039 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha848,334,692 - 48,603,370 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0848,875,966 - 49,144,988 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl848,876,026 - 49,145,790 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1848,548,799 - 48,817,529 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0848,570,236 - 48,839,457 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0848,966,471 - 49,235,573 (+)NCBIUU_Cfam_GSD_1.0
Ttll5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864027,084,218 - 27,345,683 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364884,724,909 - 4,983,318 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364884,723,314 - 4,983,926 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTLL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl798,823,871 - 99,130,915 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1798,822,338 - 99,090,076 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27104,747,706 - 104,919,117 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TTLL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12452,905,106 - 53,199,160 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2452,905,291 - 53,199,136 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605341,123,596 - 41,416,646 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttll5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473425,740,347 - 26,021,519 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ttll5
873 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:52
Count of miRNA genes:50
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000012895
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat

Markers in Region
D6Rat189  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26105,687,507 - 105,687,744 (+)MAPPERmRatBN7.2
Rnor_6.06109,897,067 - 109,897,303NCBIRnor6.0
Rnor_5.06119,205,362 - 119,205,598UniSTSRnor5.0
RGSC_v3.46110,156,748 - 110,156,985RGDRGSC3.4
RGSC_v3.46110,156,749 - 110,156,985UniSTSRGSC3.4
RGSC_v3.16110,160,279 - 110,160,516RGD
Celera6103,514,030 - 103,514,266UniSTS
SHRSP x BN Map665.7398RGD
SHRSP x BN Map665.7398UniSTS
Cytogenetic Map6q31UniSTS
R75373  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26105,700,747 - 105,700,861 (+)MAPPERmRatBN7.2
Rnor_6.06109,910,307 - 109,910,420NCBIRnor6.0
Rnor_5.06119,218,602 - 119,218,715UniSTSRnor5.0
RGSC_v3.46110,169,989 - 110,170,102UniSTSRGSC3.4
Celera6103,527,337 - 103,527,450UniSTS
Cytogenetic Map6q31UniSTS
RH128259  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26105,700,668 - 105,700,884 (+)MAPPERmRatBN7.2
Rnor_6.06109,910,228 - 109,910,443NCBIRnor6.0
Rnor_5.06119,218,523 - 119,218,738UniSTSRnor5.0
RGSC_v3.46110,169,910 - 110,170,125UniSTSRGSC3.4
Celera6103,527,258 - 103,527,473UniSTS
RH 3.4 Map6730.6UniSTS
Cytogenetic Map6q31UniSTS
RH94855  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26105,704,286 - 105,704,442 (+)MAPPERmRatBN7.2
Rnor_6.06109,913,846 - 109,914,001NCBIRnor6.0
Rnor_5.06119,222,141 - 119,222,296UniSTSRnor5.0
RGSC_v3.46110,173,528 - 110,173,683UniSTSRGSC3.4
Celera6103,530,874 - 103,531,029UniSTS
RH 3.4 Map6742.1UniSTS
Cytogenetic Map6q31UniSTS
AW530674  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26105,633,311 - 105,633,463 (+)MAPPERmRatBN7.2
Rnor_6.06109,842,791 - 109,842,942NCBIRnor6.0
Rnor_5.06119,151,086 - 119,151,237UniSTSRnor5.0
RGSC_v3.46110,102,556 - 110,102,707UniSTSRGSC3.4
Celera6103,459,859 - 103,460,010UniSTS
RH 3.4 Map6731.6UniSTS
Cytogenetic Map6q31UniSTS
RH138315  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26105,596,383 - 105,596,541 (+)MAPPERmRatBN7.2
Rnor_6.06109,805,659 - 109,805,816NCBIRnor6.0
Rnor_5.06119,113,954 - 119,114,111UniSTSRnor5.0
RGSC_v3.46110,065,633 - 110,065,790UniSTSRGSC3.4
Celera6103,422,941 - 103,423,098UniSTS
RH 3.4 Map6731.59UniSTS
Cytogenetic Map6q31UniSTS
RH125218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26105,700,748 - 105,700,886 (+)MAPPERmRatBN7.2
Rnor_6.06109,910,308 - 109,910,445NCBIRnor6.0
Rnor_5.06119,218,603 - 119,218,740UniSTSRnor5.0
RGSC_v3.46110,169,990 - 110,170,127UniSTSRGSC3.4
Celera6103,527,338 - 103,527,475UniSTS
Cytogenetic Map6q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 10 2 8 2 74 18 41 11
Low 3 37 47 39 11 39 8 11 17 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000012895   ⟹   ENSRNOP00000012895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6105,483,191 - 105,700,911 (+)Ensembl
Rnor_6.0 Ensembl6109,710,781 - 109,879,607 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096708   ⟹   ENSRNOP00000078338
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6105,483,191 - 105,700,911 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106283   ⟹   ENSRNOP00000092001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6105,483,191 - 105,700,934 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108478   ⟹   ENSRNOP00000090702
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6105,483,191 - 105,700,934 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111706   ⟹   ENSRNOP00000097918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6105,483,191 - 105,550,091 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115883   ⟹   ENSRNOP00000088846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6105,483,191 - 105,542,498 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000120049   ⟹   ENSRNOP00000094535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6105,483,191 - 105,700,911 (+)Ensembl
RefSeq Acc Id: NM_001427290   ⟹   NP_001414219
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,098 - 111,431,892 (+)NCBI
RefSeq Acc Id: XM_039113310   ⟹   XP_038969238
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,254 - 111,431,286 (+)NCBI
mRatBN7.26105,483,310 - 105,700,920 (+)NCBI
RefSeq Acc Id: XM_039113311   ⟹   XP_038969239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,077 - 111,431,286 (+)NCBI
mRatBN7.26105,483,091 - 105,700,919 (+)NCBI
RefSeq Acc Id: XM_039113312   ⟹   XP_038969240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,048 - 111,431,286 (+)NCBI
mRatBN7.26105,483,091 - 105,700,919 (+)NCBI
RefSeq Acc Id: XM_039113313   ⟹   XP_038969241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,048 - 111,431,891 (+)NCBI
mRatBN7.26105,483,091 - 105,700,919 (+)NCBI
RefSeq Acc Id: XM_039113314   ⟹   XP_038969242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,048 - 111,431,286 (+)NCBI
mRatBN7.26105,483,091 - 105,700,919 (+)NCBI
RefSeq Acc Id: XM_039113315   ⟹   XP_038969243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,048 - 111,431,891 (+)NCBI
mRatBN7.26105,483,091 - 105,700,919 (+)NCBI
RefSeq Acc Id: XM_039113316   ⟹   XP_038969244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,219,982 - 111,431,286 (+)NCBI
mRatBN7.26105,488,985 - 105,700,920 (+)NCBI
RefSeq Acc Id: XM_039113317   ⟹   XP_038969245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,048 - 111,431,286 (+)NCBI
mRatBN7.26105,483,091 - 105,700,919 (+)NCBI
RefSeq Acc Id: XM_039113318   ⟹   XP_038969246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,048 - 111,431,286 (+)NCBI
mRatBN7.26105,483,091 - 105,700,919 (+)NCBI
RefSeq Acc Id: XM_039113319   ⟹   XP_038969247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,233,905 - 111,431,286 (+)NCBI
mRatBN7.26105,502,918 - 105,700,920 (+)NCBI
RefSeq Acc Id: XM_039113320   ⟹   XP_038969248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,245,185 - 111,431,286 (+)NCBI
mRatBN7.26105,514,199 - 105,700,920 (+)NCBI
RefSeq Acc Id: XM_039113322   ⟹   XP_038969250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,279,291 - 111,431,286 (+)NCBI
mRatBN7.26105,548,297 - 105,700,920 (+)NCBI
RefSeq Acc Id: XM_039113323   ⟹   XP_038969251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,286,526 - 111,431,286 (+)NCBI
mRatBN7.26105,555,542 - 105,700,920 (+)NCBI
RefSeq Acc Id: XM_039113324   ⟹   XP_038969252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,279,282 - 111,431,286 (+)NCBI
mRatBN7.26105,548,297 - 105,700,920 (+)NCBI
RefSeq Acc Id: XM_039113325   ⟹   XP_038969253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,297,058 - 111,431,286 (+)NCBI
mRatBN7.26105,566,075 - 105,700,920 (+)NCBI
RefSeq Acc Id: XM_039113326   ⟹   XP_038969254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,048 - 111,302,053 (+)NCBI
mRatBN7.26105,483,091 - 105,570,965 (+)NCBI
RefSeq Acc Id: XM_063261755   ⟹   XP_063117825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,048 - 111,431,891 (+)NCBI
RefSeq Acc Id: XM_063261756   ⟹   XP_063117826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86111,214,242 - 111,431,891 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000012895   ⟸   ENSRNOT00000012895
RefSeq Acc Id: XP_038969239   ⟸   XM_039113311
- Peptide Label: isoform X1
- UniProtKB: D3ZAA1 (UniProtKB/TrEMBL),   A0A8I6GJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969241   ⟸   XM_039113313
- Peptide Label: isoform X3
- UniProtKB: A0A8I6ACV1 (UniProtKB/TrEMBL),   A0A8I6GJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969243   ⟸   XM_039113315
- Peptide Label: isoform X5
- UniProtKB: A0A8I6GJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969240   ⟸   XM_039113312
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969245   ⟸   XM_039113317
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AL69 (UniProtKB/TrEMBL),   A0A8I6GJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969246   ⟸   XM_039113318
- Peptide Label: isoform X8
- UniProtKB: A0A8I6GJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969242   ⟸   XM_039113314
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZKQ8 (UniProtKB/TrEMBL),   A0A8I6GJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969254   ⟸   XM_039113326
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038969238   ⟸   XM_039113310
- Peptide Label: isoform X1
- UniProtKB: D3ZAA1 (UniProtKB/TrEMBL),   A0A8I6GJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969244   ⟸   XM_039113316
- Peptide Label: isoform X6
- UniProtKB: A0A8I6GJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969247   ⟸   XM_039113319
- Peptide Label: isoform X9
- UniProtKB: A0A8I6GJ32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969248   ⟸   XM_039113320
- Peptide Label: isoform X11
- UniProtKB: A6JE47 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969250   ⟸   XM_039113322
- Peptide Label: isoform X12
- UniProtKB: A6JE47 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969252   ⟸   XM_039113324
- Peptide Label: isoform X13
- UniProtKB: A6JE47 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969251   ⟸   XM_039113323
- Peptide Label: isoform X13
- UniProtKB: A6JE47 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969253   ⟸   XM_039113325
- Peptide Label: isoform X14
- UniProtKB: A6JE50 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000097918   ⟸   ENSRNOT00000111706
RefSeq Acc Id: ENSRNOP00000092001   ⟸   ENSRNOT00000106283
RefSeq Acc Id: ENSRNOP00000094535   ⟸   ENSRNOT00000120049
RefSeq Acc Id: ENSRNOP00000088846   ⟸   ENSRNOT00000115883
RefSeq Acc Id: ENSRNOP00000078338   ⟸   ENSRNOT00000096708
RefSeq Acc Id: ENSRNOP00000090702   ⟸   ENSRNOT00000108478
RefSeq Acc Id: XP_063117825   ⟸   XM_063261755
- Peptide Label: isoform X10
RefSeq Acc Id: NP_001414219   ⟸   NM_001427290
- UniProtKB: D3ZAA1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117826   ⟸   XM_063261756
- Peptide Label: isoform X10

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAA1-F1-model_v2 AlphaFold D3ZAA1 1-1230 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563583 AgrOrtholog
BioCyc Gene G2FUF-36763 BioCyc
Ensembl Genes ENSRNOG00000009318 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012895.8 UniProtKB/TrEMBL
  ENSRNOT00000096708.1 UniProtKB/TrEMBL
  ENSRNOT00000106283.1 UniProtKB/TrEMBL
  ENSRNOT00000108478.1 UniProtKB/TrEMBL
  ENSRNOT00000111706.1 UniProtKB/TrEMBL
  ENSRNOT00000115883.1 UniProtKB/TrEMBL
  ENSRNOT00000120049.1 UniProtKB/TrEMBL
Gene3D-CATH ATP-grasp fold, B domain UniProtKB/TrEMBL
InterPro TTL/TTLL_fam UniProtKB/TrEMBL
NCBI Gene 299208 ENTREZGENE
PANTHER TUBULIN POLYGLUTAMYLASE UniProtKB/TrEMBL
  TUBULIN POLYGLUTAMYLASE TTLL5 UniProtKB/TrEMBL
Pfam TTL UniProtKB/TrEMBL
PhenoGen Ttll5 PhenoGen
PROSITE TTL UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009318 RatGTEx
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/TrEMBL
UniProt A0A8I5ZKQ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7C7_RAT UniProtKB/TrEMBL
  A0A8I6ACV1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AL69 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATV4_RAT UniProtKB/TrEMBL
  A0A8I6GJ32 ENTREZGENE, UniProtKB/TrEMBL
  A6JE47 ENTREZGENE, UniProtKB/TrEMBL
  A6JE50 ENTREZGENE, UniProtKB/TrEMBL
  D3ZAA1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Ttll5  tubulin tyrosine ligase like 5  Ttll5  tubulin tyrosine ligase-like family, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-11-25 Ttll5  tubulin tyrosine ligase-like family, member 5  RGD1563583  similar to mKIAA0998 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1563583  similar to mKIAA0998 protein   RGD1563583_predicted  similar to mKIAA0998 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563583_predicted  similar to mKIAA0998 protein (predicted)  LOC299208  similar to mKIAA0998 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC299208  similar to mKIAA0998 protein      Symbol and Name status set to provisional 70820 PROVISIONAL