Uggt2 (UDP-glucose glycoprotein glucosyltransferase 2) - Rat Genome Database

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Gene: Uggt2 (UDP-glucose glycoprotein glucosyltransferase 2) Rattus norvegicus
Analyze
Symbol: Uggt2 (Ensembl: AABR07019403.1)
Name: UDP-glucose glycoprotein glucosyltransferase 2
RGD ID: 1563520
Description: Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity. Predicted to be involved in UDP-glucosylation and protein glycosylation. Predicted to be located in membrane. Predicted to be part of protein-containing complex. Orthologous to human UGGT2 (UDP-glucose glycoprotein glucosyltransferase 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cisplatin.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC290489; LOC361091; RGD1562426; RGD1563520; similar to UDP-glucose ceramide glucosyltransferase-like 2; similar to UDP-glucose:glycoprotein glucosyltransferase 2; UDP-glucose:glycoprotein glucosyltransferase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815102,480,239 - 102,646,291 (-)NCBIGRCr8
mRatBN7.21596,074,557 - 96,239,365 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1596,074,564 - 96,237,806 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.015104,235,678 - 104,405,308 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.015107,658,797 - 107,826,854 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415103,924,808 - 104,031,923 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1594,924,254 - 95,082,944 (-)NCBICelera
Cytogenetic Map15q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:23349634  


Genomics

Comparative Map Data
Uggt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815102,480,239 - 102,646,291 (-)NCBIGRCr8
mRatBN7.21596,074,557 - 96,239,365 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1596,074,564 - 96,237,806 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.015104,235,678 - 104,405,308 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.015107,658,797 - 107,826,854 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415103,924,808 - 104,031,923 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1594,924,254 - 95,082,944 (-)NCBICelera
Cytogenetic Map15q24NCBI
UGGT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381395,801,580 - 96,053,401 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1395,801,580 - 96,053,482 (-)EnsemblGRCh38hg38GRCh38
GRCh371396,453,834 - 96,705,655 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361395,251,835 - 95,503,638 (-)NCBINCBI36Build 36hg18NCBI36
Build 341395,251,837 - 95,503,638NCBI
Celera1377,301,630 - 77,553,211 (-)NCBICelera
Cytogenetic Map13q32.1NCBI
HuRef1377,051,354 - 77,303,083 (-)NCBIHuRef
CHM1_11396,423,994 - 96,676,120 (-)NCBICHM1_1
T2T-CHM13v2.01395,006,150 - 95,257,608 (-)NCBIT2T-CHM13v2.0
Uggt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914119,219,177 - 119,337,208 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14119,222,451 - 119,336,842 (-)EnsemblGRCm39 Ensembl
GRCm3814118,982,006 - 119,099,796 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14118,985,039 - 119,099,430 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714119,384,207 - 119,498,656 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614118,120,166 - 118,234,618 (-)NCBIMGSCv36mm8
Celera14117,540,236 - 117,654,249 (-)NCBICelera
Cytogenetic Map14E4NCBI
cM Map1462.61NCBI
Uggt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540414,165,816 - 14,356,293 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540414,165,686 - 14,354,207 (+)NCBIChiLan1.0ChiLan1.0
UGGT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21497,326,472 - 97,577,631 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11395,993,472 - 96,246,498 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01376,970,139 - 77,219,241 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11396,124,714 - 96,377,116 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1396,124,714 - 96,377,116 (-)Ensemblpanpan1.1panPan2
UGGT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12246,407,342 - 46,591,595 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2246,309,326 - 46,591,803 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2246,190,345 - 46,374,672 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02246,834,657 - 47,019,314 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2246,834,844 - 47,019,353 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12246,497,875 - 46,682,198 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02246,531,021 - 46,715,320 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02246,536,437 - 46,720,772 (-)NCBIUU_Cfam_GSD_1.0
Uggt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945181,901,127 - 182,083,316 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647213,868,979 - 14,050,770 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647213,868,865 - 14,051,269 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UGGT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1165,307,168 - 65,476,544 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11165,307,208 - 65,476,791 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21172,281,219 - 72,406,478 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UGGT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1374,584,872 - 74,806,927 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl374,588,049 - 74,806,818 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604631,016,329 - 31,244,090 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uggt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248792,450,316 - 2,642,954 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248792,449,128 - 2,642,884 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Uggt2
1343 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:22
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000072606
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)157369051899794247Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1575788062101769107Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1575788062101769107Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1576306099101769107Rat
1300118Bp190Blood pressure QTL 1902.94arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)158226252098288169Rat
1300120Kidm7Kidney mass QTL 73.55kidney mass (VT:0002707)left kidney wet weight to body weight ratio (CMO:0001954)158226252098288169Rat

Markers in Region
BE119155  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1595,057,116 - 95,057,316UniSTS
RH 3.4 Map15649.6UniSTS
Cytogenetic Map15q24UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_063274902   ⟹   XP_063130972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815102,480,239 - 102,646,290 (-)NCBI
RefSeq Acc Id: XM_063274903   ⟹   XP_063130973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815102,480,239 - 102,646,290 (-)NCBI
RefSeq Acc Id: XM_063274904   ⟹   XP_063130974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815102,511,307 - 102,646,291 (-)NCBI
RefSeq Acc Id: XM_063274905   ⟹   XP_063130975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815102,480,239 - 102,634,075 (-)NCBI
RefSeq Acc Id: XM_063274906   ⟹   XP_063130976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815102,511,718 - 102,646,290 (-)NCBI
RefSeq Acc Id: XM_063274907   ⟹   XP_063130977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815102,533,715 - 102,646,291 (-)NCBI
RefSeq Acc Id: XM_063274908   ⟹   XP_063130978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815102,534,072 - 102,646,290 (-)NCBI
RefSeq Acc Id: XM_063274909   ⟹   XP_063130979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815102,480,239 - 102,580,536 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_063130973   ⟸   XM_063274903
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063130972   ⟸   XM_063274902
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063130975   ⟸   XM_063274905
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063130979   ⟸   XM_063274909
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063130974   ⟸   XM_063274904
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063130976   ⟸   XM_063274906
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063130977   ⟸   XM_063274907
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063130978   ⟸   XM_063274908
- Peptide Label: isoform X7
Protein Domains
UGGT thioredoxin-like

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563520 AgrOrtholog
BioCyc Gene G2FUF-12429 BioCyc
Ensembl Genes ENSRNOG00000058057 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000086015.2 UniProtKB/TrEMBL
InterPro UDP-g_GGtrans UniProtKB/TrEMBL
  UGGT_TRXL_1 UniProtKB/TrEMBL
NCBI Gene 361091 ENTREZGENE
PANTHER PTHR11226 UniProtKB/TrEMBL
  UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE 2 UniProtKB/TrEMBL
Pfam Thioredoxin_12 UniProtKB/TrEMBL
PhenoGen Uggt2 PhenoGen
RatGTEx ENSRNOG00000058057 RatGTEx
UniProt A0A8I6GM60_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Uggt2  UDP-glucose glycoprotein glucosyltransferase 2  RGD1562426  similar to UDP-glucose:glycoprotein glucosyltransferase 2  Data merged from RGD:1562426 737654 PROVISIONAL
2014-07-28 Uggt2  UDP-glucose glycoprotein glucosyltransferase 2  RGD1563520  similar to UDP-glucose ceramide glucosyltransferase-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1563520  similar to UDP-glucose ceramide glucosyltransferase-like 2   RGD1563520_predicted  similar to UDP-glucose ceramide glucosyltransferase-like 2 (predicted)  'predicted' is removed 2292626 APPROVED
2008-04-30 RGD1562426  similar to UDP-glucose:glycoprotein glucosyltransferase 2   RGD1562426_predicted  similar to UDP-glucose:glycoprotein glucosyltransferase 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563520_predicted  similar to UDP-glucose ceramide glucosyltransferase-like 2 (predicted)  LOC361091  similar to UDP-glucose ceramide glucosyltransferase-like 2  Symbol and Name status set to approved 1299863 APPROVED
2006-03-07 RGD1562426_predicted  similar to UDP-glucose:glycoprotein glucosyltransferase 2 (predicted)  LOC290489  similar to UDP-glucose:glycoprotein glucosyltransferase 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC361091  similar to UDP-glucose ceramide glucosyltransferase-like 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-02-09 LOC290489  similar to UDP-glucose:glycoprotein glucosyltransferase 2      Symbol and Name status set to provisional 70820 PROVISIONAL