Haus7 (HAUS augmin-like complex, subunit 7) - Rat Genome Database

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Gene: Haus7 (HAUS augmin-like complex, subunit 7) Rattus norvegicus
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Symbol: Haus7
Name: HAUS augmin-like complex, subunit 7
RGD ID: 1562991
Description: Predicted to enable microtubule minus-end binding activity and thioesterase binding activity. Predicted to be involved in centrosome cycle and spindle assembly. Predicted to be located in microtubule cytoskeleton; nucleolus; and plasma membrane. Predicted to be part of HAUS complex. Orthologous to human HAUS7 (HAUS augmin like complex subunit 7); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HAUS augmin-like complex subunit 7; LOC293844; RGD1562991; similar to UCH37-interacting protein 1; UCHL5 interacting protein; Uchl5ip
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,306,320 - 156,331,940 (-)NCBIGRCr8
mRatBN7.2X151,154,979 - 151,174,441 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,154,979 - 151,180,577 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX153,296,141 - 153,315,224 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X156,859,352 - 156,878,435 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X154,531,185 - 154,550,268 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,347,222 - 157,372,796 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX157,353,577 - 157,372,809 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01153,095,311 - 153,120,880 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X159,337,591 - 159,356,655 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1136,715,537 - 136,734,620 (+)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
centrosome cycle  (IBA,ISO)
spindle assembly  (IBA,ISO)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11163772   PMID:12477932   PMID:19369198   PMID:19427217   PMID:21399614  


Genomics

Comparative Map Data
Haus7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,306,320 - 156,331,940 (-)NCBIGRCr8
mRatBN7.2X151,154,979 - 151,174,441 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,154,979 - 151,180,577 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX153,296,141 - 153,315,224 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X156,859,352 - 156,878,435 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X154,531,185 - 154,550,268 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,347,222 - 157,372,796 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX157,353,577 - 157,372,809 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01153,095,311 - 153,120,880 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X159,337,591 - 159,356,655 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1136,715,537 - 136,734,620 (+)NCBICelera
Cytogenetic MapXq37NCBI
HAUS7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X153,447,668 - 153,495,465 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX153,447,668 - 153,495,516 (-)EnsemblGRCh38hg38GRCh38
GRCh37X152,713,126 - 152,760,923 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X152,366,318 - 152,389,283 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX152,946,833 - 152,970,312 (-)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX141,372,261 - 141,419,460 (-)NCBIHuRef
CHM1_1X152,587,548 - 152,635,492 (-)NCBICHM1_1
T2T-CHM13v2.0X151,721,251 - 151,769,038 (-)NCBIT2T-CHM13v2.0
Haus7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X72,480,921 - 72,502,635 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX72,480,921 - 72,502,650 (-)EnsemblGRCm39 Ensembl
GRCm38X73,437,315 - 73,459,029 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX73,437,315 - 73,459,044 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X70,682,654 - 70,704,368 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X69,690,035 - 69,711,749 (-)NCBIMGSCv36mm8
CeleraX64,691,155 - 64,712,939 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.32NCBI
Haus7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580210,820 - 230,734 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955580210,799 - 230,450 (-)NCBIChiLan1.0ChiLan1.0
HAUS7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X153,484,903 - 153,524,280 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X153,488,507 - 153,514,688 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X142,998,240 - 143,032,602 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X152,884,656 - 152,907,620 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX152,881,714 - 152,907,620 (-)Ensemblpanpan1.1panPan2
HAUS7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X121,264,824 - 121,296,712 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX121,266,584 - 121,297,076 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX106,597,285 - 106,627,487 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X123,524,855 - 123,550,859 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X120,178,899 - 120,209,102 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X122,694,013 - 122,724,221 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X122,456,069 - 122,486,247 (-)NCBIUU_Cfam_GSD_1.0
Haus7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X118,584,145 - 118,612,356 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936809321,497 - 350,110 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936809321,906 - 350,105 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HAUS7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,234,736 - 124,258,098 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,234,735 - 124,258,133 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X141,801,317 - 141,821,536 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HAUS7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X127,882,121 - 127,930,089 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX127,878,900 - 127,902,344 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606565,743,859 - 65,788,401 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Haus7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624946190,127 - 210,497 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624946190,065 - 210,003 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Haus7
2 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:353
Count of miRNA genes:202
Interacting mature miRNAs:230
Transcripts:ENSRNOT00000046264
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 33 20 10 20 1 1 68 35 41 6 1
Low 17 24 21 9 21 7 10 6 5 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000080691   ⟹   ENSRNOP00000074313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,154,984 - 151,174,045 (-)Ensembl
Rnor_6.0 EnsemblX157,353,730 - 157,372,791 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090596   ⟹   ENSRNOP00000070747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,154,979 - 151,180,577 (-)Ensembl
Rnor_6.0 EnsemblX157,353,577 - 157,372,809 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115770   ⟹   ENSRNOP00000088411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,154,979 - 151,180,574 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117891   ⟹   ENSRNOP00000079527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX151,154,982 - 151,180,574 (-)Ensembl
RefSeq Acc Id: NM_001277272   ⟹   NP_001264201
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,306,320 - 156,325,403 (-)NCBI
mRatBN7.2X151,154,979 - 151,174,062 (-)NCBI
Rnor_6.0X157,353,713 - 157,372,796 (+)NCBI
Rnor_5.01153,095,311 - 153,120,880 (+)NCBI
Celera1136,715,537 - 136,734,620 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099522   ⟹   XP_038955450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,306,322 - 156,331,937 (-)NCBI
mRatBN7.2X151,154,981 - 151,174,441 (-)NCBI
RefSeq Acc Id: XM_063279832   ⟹   XP_063135902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,306,322 - 156,331,937 (-)NCBI
RefSeq Acc Id: XM_063279833   ⟹   XP_063135903
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,316,987 - 156,331,940 (-)NCBI
RefSeq Acc Id: XM_063279834   ⟹   XP_063135904
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,317,222 - 156,331,940 (-)NCBI
RefSeq Acc Id: XR_010061174
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,317,069 - 156,331,940 (-)NCBI
RefSeq Acc Id: NP_001264201   ⟸   NM_001277272
- UniProtKB: B0BN53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074313   ⟸   ENSRNOT00000080691
RefSeq Acc Id: ENSRNOP00000070747   ⟸   ENSRNOT00000090596
RefSeq Acc Id: XP_038955450   ⟸   XM_039099522
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYQ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000088411   ⟸   ENSRNOT00000115770
RefSeq Acc Id: ENSRNOP00000079527   ⟸   ENSRNOT00000117891
RefSeq Acc Id: XP_063135902   ⟸   XM_063279832
- Peptide Label: isoform X2
- UniProtKB: B0BN53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135903   ⟸   XM_063279833
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063135904   ⟸   XM_063279834
- Peptide Label: isoform X4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BN53-F1-model_v2 AlphaFold B0BN53 1-368 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702065
Promoter ID:EPDNEW_R12584
Type:initiation region
Name:Haus7_1
Description:HAUS augmin-like complex, subunit 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X157,353,777 - 157,353,837EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562991 AgrOrtholog
BioCyc Gene G2FUF-675 BioCyc
Ensembl Genes ENSRNOG00000055648 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000080691.2 UniProtKB/TrEMBL
  ENSRNOT00000090596.2 UniProtKB/TrEMBL
  ENSRNOT00000115770.1 UniProtKB/TrEMBL
  ENSRNOT00000117891.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7134953 IMAGE-MGC_LOAD
  IMAGE:8375819 IMAGE-MGC_LOAD
InterPro Haus7-like UniProtKB/TrEMBL
KEGG Report rno:293844 UniProtKB/TrEMBL
MGC_CLONE MGC:125119 IMAGE-MGC_LOAD
  MGC:187705 IMAGE-MGC_LOAD
NCBI Gene 293844 ENTREZGENE
PANTHER HAUS AUGMIN-LIKE COMPLEX SUBUNIT 7 UniProtKB/TrEMBL
  PTHR14352 UniProtKB/TrEMBL
PhenoGen Haus7 PhenoGen
RatGTEx ENSRNOG00000055648 RatGTEx
UniProt A0A0G2JYQ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A6G6_RAT UniProtKB/TrEMBL
  A0A8I6G3F4_RAT UniProtKB/TrEMBL
  B0BN53 ENTREZGENE, UniProtKB/TrEMBL
  Q3ZAU9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Haus7  HAUS augmin-like complex, subunit 7  Uchl5ip  UCHL5 interacting protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Uchl5ip  UCHL5 interacting protein  RGD1562991_predicted  similar to UCH37-interacting protein 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1562991_predicted  similar to UCH37-interacting protein 1 (predicted)  LOC293844  similar to UCH37-interacting protein 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC293844  similar to UCH37-interacting protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL