Sema4c (semaphorin 4C) - Rat Genome Database

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Gene: Sema4c (semaphorin 4C) Rattus norvegicus
Analyze
Symbol: Sema4c
Name: semaphorin 4C
RGD ID: 1562837
Description: Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including negative regulation of axon extension involved in axon guidance; nervous system development; and positive regulation of stress-activated MAPK cascade. Predicted to be located in postsynaptic density. Predicted to be active in plasma membrane and synaptic vesicle membrane. Orthologous to human SEMA4C (semaphorin 4C); INTERACTS WITH acetamide; bisphenol A; cefaloridine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC301346; RGD1562837; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C; semaphorin-4C; similar to Semaphorin 4C precursor (Semaphorin I); similar to Semaphorin 4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8946,287,540 - 46,298,041 (-)NCBIGRCr8
mRatBN7.2938,791,668 - 38,802,171 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl938,791,670 - 38,802,128 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx947,295,194 - 47,305,656 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0952,410,468 - 52,420,923 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0950,692,369 - 50,702,824 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0943,129,413 - 43,140,442 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl943,129,415 - 43,139,870 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0942,783,319 - 42,793,776 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4935,492,647 - 35,503,102 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera936,558,044 - 36,568,492 (-)NCBICelera
Cytogenetic Map9q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11134026   PMID:15811348   PMID:17498836   PMID:19189244   PMID:21122816   PMID:22664934   PMID:37482144  


Genomics

Comparative Map Data
Sema4c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8946,287,540 - 46,298,041 (-)NCBIGRCr8
mRatBN7.2938,791,668 - 38,802,171 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl938,791,670 - 38,802,128 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx947,295,194 - 47,305,656 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0952,410,468 - 52,420,923 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0950,692,369 - 50,702,824 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0943,129,413 - 43,140,442 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl943,129,415 - 43,139,870 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0942,783,319 - 42,793,776 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4935,492,647 - 35,503,102 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera936,558,044 - 36,568,492 (-)NCBICelera
Cytogenetic Map9q21NCBI
SEMA4C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38296,859,718 - 96,870,830 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl296,859,718 - 96,870,757 (-)EnsemblGRCh38hg38GRCh38
GRCh37297,525,455 - 97,535,817 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36296,889,200 - 96,899,462 (-)NCBINCBI36Build 36hg18NCBI36
Build 34296,947,352 - 96,957,582NCBI
Celera291,965,635 - 91,975,934 (-)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef291,485,571 - 91,495,645 (-)NCBIHuRef
CHM1_1297,530,409 - 97,540,671 (-)NCBICHM1_1
T2T-CHM13v2.0297,366,349 - 97,377,098 (-)NCBIT2T-CHM13v2.0
Sema4c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39136,587,720 - 36,599,780 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl136,587,720 - 36,597,430 (-)EnsemblGRCm39 Ensembl
GRCm38136,548,639 - 36,560,699 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl136,548,639 - 36,558,349 (-)EnsemblGRCm38mm10GRCm38
MGSCv37136,605,487 - 36,615,226 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36136,493,186 - 36,504,590 (-)NCBIMGSCv36mm8
Celera136,335,454 - 36,345,188 (-)NCBICelera
Cytogenetic Map1BNCBI
cM Map115.32NCBI
Sema4c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554704,213,006 - 4,220,169 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554704,213,006 - 4,220,167 (-)NCBIChiLan1.0ChiLan1.0
SEMA4C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21231,437,516 - 31,448,909 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A31,438,188 - 31,451,673 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A102,443,333 - 102,455,176 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A97,779,357 - 97,788,242 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A97,780,242 - 97,787,341 (-)Ensemblpanpan1.1panPan2
SEMA4C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11045,105,701 - 45,116,504 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1045,106,666 - 45,115,592 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1045,032,228 - 45,043,112 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01045,981,562 - 45,992,443 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1045,982,132 - 45,992,433 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11045,693,071 - 45,703,955 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01045,979,501 - 45,990,386 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01046,162,896 - 46,173,783 (+)NCBIUU_Cfam_GSD_1.0
Sema4c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629283,541,170 - 83,551,897 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936744793,898 - 804,642 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936744794,127 - 804,618 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEMA4C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl356,750,760 - 56,760,828 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1356,750,745 - 56,760,835 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2359,247,355 - 59,256,799 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEMA4C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1141,189,547 - 1,199,906 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl141,189,495 - 1,199,446 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041168,626,646 - 168,637,041 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sema4c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247492,737,251 - 2,745,979 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247492,737,251 - 2,747,540 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sema4c
32 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:505
Count of miRNA genes:266
Interacting mature miRNAs:326
Transcripts:ENSRNOT00000021956
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 24 4 4 4 66 20 28 2
Low 3 19 52 36 19 36 8 11 8 15 13 9 8
Below cutoff 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000021956   ⟹   ENSRNOP00000021956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl938,791,670 - 38,802,128 (-)Ensembl
Rnor_6.0 Ensembl943,129,415 - 43,139,870 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000075882   ⟹   ENSRNOP00000068240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl938,791,670 - 38,802,128 (-)Ensembl
Rnor_6.0 Ensembl943,130,100 - 43,139,246 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl943,131,041 - 43,131,455 (-)Ensembl
RefSeq Acc Id: NM_001106902   ⟹   NP_001100372
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,287,542 - 46,297,998 (-)NCBI
mRatBN7.2938,791,670 - 38,802,128 (-)NCBI
Rnor_6.0943,129,415 - 43,139,870 (-)NCBI
Rnor_5.0942,783,319 - 42,793,776 (-)NCBI
RGSC_v3.4935,492,647 - 35,503,102 (-)RGD
Celera936,558,044 - 36,568,492 (-)RGD
Sequence:
RefSeq Acc Id: XM_006244758   ⟹   XP_006244820
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,287,540 - 46,295,418 (-)NCBI
mRatBN7.2938,791,668 - 38,799,549 (-)NCBI
Rnor_6.0943,129,413 - 43,137,824 (-)NCBI
Rnor_5.0942,783,319 - 42,793,776 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006244759   ⟹   XP_006244821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,287,540 - 46,297,462 (-)NCBI
mRatBN7.2938,791,668 - 38,801,428 (-)NCBI
Rnor_6.0943,129,413 - 43,139,478 (-)NCBI
Rnor_5.0942,783,319 - 42,793,776 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006244760   ⟹   XP_006244822
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,287,540 - 46,297,134 (-)NCBI
mRatBN7.2938,791,668 - 38,799,947 (-)NCBI
Rnor_6.0943,129,413 - 43,137,824 (-)NCBI
Rnor_5.0942,783,319 - 42,793,776 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766995   ⟹   XP_008765217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,287,540 - 46,297,461 (-)NCBI
mRatBN7.2938,791,668 - 38,801,537 (-)NCBI
Rnor_6.0943,129,413 - 43,139,478 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766996   ⟹   XP_008765218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,287,540 - 46,298,041 (-)NCBI
mRatBN7.2938,791,668 - 38,802,171 (-)NCBI
Rnor_6.0943,129,413 - 43,140,442 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596339   ⟹   XP_017451828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,287,540 - 46,298,041 (-)NCBI
mRatBN7.2938,791,668 - 38,802,171 (-)NCBI
Rnor_6.0943,129,413 - 43,140,442 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083220   ⟹   XP_038939148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,287,540 - 46,297,134 (-)NCBI
mRatBN7.2938,791,668 - 38,799,947 (-)NCBI
RefSeq Acc Id: XM_039083221   ⟹   XP_038939149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,287,540 - 46,297,134 (-)NCBI
mRatBN7.2938,791,668 - 38,799,947 (-)NCBI
RefSeq Acc Id: XM_039083222   ⟹   XP_038939150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8946,287,540 - 46,293,242 (-)NCBI
mRatBN7.2938,791,668 - 38,797,388 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001100372   ⟸   NM_001106902
- Peptide Label: precursor
- UniProtKB: D4A9J3 (UniProtKB/TrEMBL),   A6INE2 (UniProtKB/TrEMBL),   A0A096MJS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244821   ⟸   XM_006244759
- Peptide Label: isoform X2
- UniProtKB: D4A9J3 (UniProtKB/TrEMBL),   A6INE2 (UniProtKB/TrEMBL),   A0A096MJS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244822   ⟸   XM_006244760
- Peptide Label: isoform X2
- UniProtKB: D4A9J3 (UniProtKB/TrEMBL),   A6INE2 (UniProtKB/TrEMBL),   A0A096MJS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244820   ⟸   XM_006244758
- Peptide Label: isoform X1
- UniProtKB: A0A096MJS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765218   ⟸   XM_008766996
- Peptide Label: isoform X2
- UniProtKB: D4A9J3 (UniProtKB/TrEMBL),   A6INE2 (UniProtKB/TrEMBL),   A0A096MJS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765217   ⟸   XM_008766995
- Peptide Label: isoform X2
- UniProtKB: D4A9J3 (UniProtKB/TrEMBL),   A6INE2 (UniProtKB/TrEMBL),   A0A096MJS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451828   ⟸   XM_017596339
- Peptide Label: isoform X2
- UniProtKB: D4A9J3 (UniProtKB/TrEMBL),   A6INE2 (UniProtKB/TrEMBL),   A0A096MJS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000021956   ⟸   ENSRNOT00000021956
RefSeq Acc Id: ENSRNOP00000068240   ⟸   ENSRNOT00000075882
RefSeq Acc Id: XP_038939149   ⟸   XM_039083221
- Peptide Label: isoform X2
- UniProtKB: D4A9J3 (UniProtKB/TrEMBL),   A6INE2 (UniProtKB/TrEMBL),   A0A096MJS2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939148   ⟸   XM_039083220
- Peptide Label: isoform X2
- UniProtKB: D4A9J3 (UniProtKB/TrEMBL),   A6INE2 (UniProtKB/TrEMBL),   A0A096MJS2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939150   ⟸   XM_039083222
- Peptide Label: isoform X3
- UniProtKB: A0A096MJS2 (UniProtKB/TrEMBL)
Protein Domains
Ig-like   Sema

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9J3-F1-model_v2 AlphaFold D4A9J3 1-834 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696618
Promoter ID:EPDNEW_R7131
Type:single initiation site
Name:Sema4c_1
Description:semaphorin 4C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0943,139,265 - 43,139,325EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562837 AgrOrtholog
BioCyc Gene G2FUF-27806 BioCyc
Ensembl Genes ENSRNOG00000016254 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021956 ENTREZGENE
  ENSRNOT00000021956.7 UniProtKB/TrEMBL
  ENSRNOT00000075882.2 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Plexin-like_fold UniProtKB/TrEMBL
  Plexin_repeat UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  Semaphorin UniProtKB/TrEMBL
  Semaphorin/CD100_Ag UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
KEGG Report rno:301346 UniProtKB/TrEMBL
NCBI Gene 301346 ENTREZGENE
PANTHER PTHR11036 UniProtKB/TrEMBL
  SEMAPHORIN-4C UniProtKB/TrEMBL
Pfam PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
PhenoGen Sema4c PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
  SEMA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016254 RatGTEx
SMART PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A096MJS2 ENTREZGENE, UniProtKB/TrEMBL
  A6INE2 ENTREZGENE, UniProtKB/TrEMBL
  D4A9J3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-21 Sema4c  semaphorin 4C  Sema4c  sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Sema4c  sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C   Sema4c_predicted  sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Sema4c_predicted  sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C (predicted)  RGD1562837_predicted  similar to Semaphorin 4C precursor (Semaphorin I) (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-10 RGD1562837_predicted  similar to Semaphorin 4C precursor (Semaphorin I) (predicted)    similar to Semaphorin 4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F) (predicted)  Name updated 1299863 APPROVED
2006-03-07 RGD1562837_predicted  similar to Semaphorin 4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F) (predicted)  LOC301346  similar to Semaphorin 4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC301346  similar to Semaphorin 4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F)      Symbol and Name status set to provisional 70820 PROVISIONAL