Mageb1l1 (MAGE family member B1-like 1) - Rat Genome Database

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Gene: Mageb1l1 (MAGE family member B1-like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Mageb1l1
Name: MAGE family member B1-like 1
RGD ID: 1562439
Description: INVOLVED IN negative regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleus (inferred); INTERACTS WITH acrylamide
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC503441; Mageb4; melanoma antigen family B 1-like 1; melanoma antigen family B, 4; melanoma-associated antigen B2-like; melanoma-associated antigen B4-like; RGD1562439; similar to melanoma antigen family B, 4
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X54,837,396 - 54,847,437 (-)NCBIGRCr8
mRatBN7.2X50,886,626 - 50,896,669 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.0X54,864,441 - 54,931,190 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X55,067,957 - 55,069,218 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X73,137,270 - 73,146,936 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX51,419,664 - 51,429,680 (-)NCBICelera
Cytogenetic MapXq21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
acrylamide  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Mageb1l1
63 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:44
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000074089
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat


Expression


Sequence


RefSeq Acc Id: NM_001408866   ⟹   NP_001395795
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X54,837,396 - 54,847,437 (-)NCBI
mRatBN7.2X50,886,626 - 50,896,669 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001395795 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000089033.1
RefSeq Acc Id: NP_001395795   ⟸   NM_001408866
- UniProtKB: A0A8I6AAQ4 (UniProtKB/TrEMBL)
Protein Domains
MAGE

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-2335 BioCyc
Ensembl Genes ENSRNOG00000048202 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000074089.3 UniProtKB/TrEMBL
Gene3D-CATH MAGE homology domain, winged helix WH1 motif UniProtKB/TrEMBL
  MAGE homology domain, winged helix WH2 motif UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
  MHD_dom UniProtKB/TrEMBL
NCBI Gene 503441 ENTREZGENE
PANTHER MELANOMA-ASSOCIATED ANTIGEN B4 UniProtKB/TrEMBL
  MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
PhenoGen Mageb1l1 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000048202 RatGTEx
SMART MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
UniProt A0A8I6AAQ4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-18 Mageb1l1  MAGE family member B1-like 1  mageb1l1  melanoma antigen family B 1-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-11 mageb1l1  melanoma antigen family B 1-like 1  Mageb4  melanoma antigen family B, 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-29 Mageb4  melanoma antigen family B, 4  RGD1562439_predicted  similar to melanoma antigen family B, 4 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1562439_predicted  similar to melanoma antigen family B, 4 (predicted)  LOC503441  similar to melanoma antigen family B, 4  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC503441  similar to melanoma antigen family B, 4      Symbol and Name status set to provisional 70820 PROVISIONAL