Spag11b (sperm associated antigen 11b) - Rat Genome Database

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Gene: Spag11b (sperm associated antigen 11b) Rattus norvegicus
Analyze
Symbol: Spag11b
Name: sperm associated antigen 11b
RGD ID: 1562239
Description: Predicted to be involved in antimicrobial humoral immune response mediated by antimicrobial peptide. Predicted to be located in extracellular region. Orthologous to human SPAG11B (sperm associated antigen 11B); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Spag11c; sperm associated antigen 11C; sperm-associated antigen 11 variant C; sperm-associated antigen 11B
RGD Orthologs
Human
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2 Ensembl1670,698,127 - 70,700,110 (-)EnsemblmRatBN7.2 Ensembl
RGSC_v3.41675,491,074 - 75,493,021 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1668,565,073 - 68,567,020 (-)NCBICelera
Cytogenetic Map16q12.5NCBI


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16033865   PMID:16411022   PMID:25657045  


Genomics

Comparative Map Data
Spag11b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2 Ensembl1670,698,127 - 70,700,110 (-)EnsemblmRatBN7.2 Ensembl
RGSC_v3.41675,491,074 - 75,493,021 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1668,565,073 - 68,567,020 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
SPAG11B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3887,447,754 - 7,463,542 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl87,442,684 - 7,463,674 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl87,847,876 - 7,868,867 (+)EnsemblGRCh38hg38GRCh38
GRCh3787,305,276 - 7,321,064 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3687,292,686 - 7,308,602 (-)NCBINCBI36Build 36hg18NCBI36
Build 3487,295,495 - 7,297,297NCBI
Cytogenetic Map8p23.1NCBI
CHM1_187,306,597 - 7,322,529 (+)NCBICHM1_1
T2T-CHM13v2.087,176,751 - 7,192,550 (-)NCBIT2T-CHM13v2.0
Spag11b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39819,190,775 - 19,193,026 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl819,190,775 - 19,193,026 (+)EnsemblGRCm39 Ensembl
GRCm38819,140,759 - 19,143,010 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl819,140,759 - 19,143,010 (+)EnsemblGRCm38mm10GRCm38
MGSCv37819,140,759 - 19,143,010 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36819,140,736 - 19,142,987 (+)NCBIMGSCv36mm8
Celera819,271,045 - 19,273,297 (+)NCBICelera
Cytogenetic Map8A1.3NCBI
cM Map810.35NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001037850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001037852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000046821   ⟹   ENSRNOP00000041418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1670,698,127 - 70,700,110 (-)Ensembl
RefSeq Acc Id: NM_001037850   ⟹   NP_001032939
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
RGSC_v3.41675,491,074 - 75,493,021 (-)RGD
Celera1668,565,073 - 68,567,020 (-)RGD
Sequence:
RefSeq Acc Id: NM_001037852   ⟹   NP_001032941
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
RGSC_v3.41675,491,074 - 75,493,021 (-)RGD
Celera1668,565,073 - 68,567,020 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001032939 (Get FASTA)   NCBI Sequence Viewer  
  NP_001032941 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040559.5
  ENSRNOP00000041418.5
Reference Protein Sequences
RefSeq Acc Id: NP_001032941   ⟸   NM_001037852
- Peptide Label: isoform 1 precursor
- UniProtKB: Q30KI9 (UniProtKB/TrEMBL),   D3ZML6 (UniProtKB/TrEMBL),   F7F947 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001032939   ⟸   NM_001037850
- Peptide Label: isoform 2 precursor
- UniProtKB: Q30KJ0 (UniProtKB/TrEMBL),   F7F947 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000041418   ⟸   ENSRNOT00000046821

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562239 AgrOrtholog
Ensembl Genes ENSRNOG00000068498 UniProtKB/TrEMBL
  ENSRNOG00000070256 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046821.7 UniProtKB/TrEMBL
  ENSRNOT00000047761.6 UniProtKB/TrEMBL
InterPro Defensin_beta UniProtKB/TrEMBL
  Sperm_Ag_HE2 UniProtKB/TrEMBL
KEGG Report rno:100362580 UniProtKB/TrEMBL
NCBI Gene 652998 ENTREZGENE
PANTHER PTHR14081 UniProtKB/TrEMBL
  SPERM-ASSOCIATED ANTIGEN 11A-RELATED UniProtKB/TrEMBL
Pfam Defensin_beta UniProtKB/TrEMBL
  Sperm_Ag_HE2 UniProtKB/TrEMBL
PhenoGen Spag11b PhenoGen
RatGTEx ENSRNOG00000068498 RatGTEx
  ENSRNOG00000070256 RatGTEx
UniProt D3ZML6 ENTREZGENE
  F7F947 ENTREZGENE, UniProtKB/TrEMBL
  Q30KI9 ENTREZGENE, UniProtKB/TrEMBL
  Q30KJ0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary D3ZML6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-29 Spag11b  sperm associated antigen 11b  Spag11c  sperm associated antigen 11C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-10-22 Spag11c  sperm associated antigen 11C  Spag11c  sperm-associated antigen 11 variant C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Spag11c  sperm-associated antigen 11 variant C      Symbol and Name status set to provisional 70820 PROVISIONAL