Plch1 (phospholipase C, eta 1) - Rat Genome Database

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Gene: Plch1 (phospholipase C, eta 1) Rattus norvegicus
Analyze
Symbol: Plch1
Name: phospholipase C, eta 1
RGD ID: 1561991
Description: Predicted to enable calcium-dependent phospholipase C activity and phosphatidylinositol phospholipase C activity. Predicted to be involved in phosphatidylinositol metabolic process; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol. Predicted to be located in cytosol; intracellular membrane-bounded organelle; and membrane. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in holoprosencephaly. Orthologous to human PLCH1 (phospholipase C eta 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1; LOC310463; phospholipase C-like 3; Plcl3; RGD1561991; similar to Hypothetical protein MGC57096
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82150,298,547 - 150,514,120 (-)NCBIGRCr8
mRatBN7.22148,148,908 - 148,363,616 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2148,148,921 - 148,364,097 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2154,861,345 - 154,959,674 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02152,910,789 - 153,009,122 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02147,543,478 - 147,641,810 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02154,256,382 - 154,468,166 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2154,256,380 - 154,418,920 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02173,640,220 - 173,849,566 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42153,467,156 - 153,562,651 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2142,435,231 - 142,522,875 (-)NCBICelera
Cytogenetic Map2q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15702972   PMID:31904090  


Genomics

Comparative Map Data
Plch1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82150,298,547 - 150,514,120 (-)NCBIGRCr8
mRatBN7.22148,148,908 - 148,363,616 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2148,148,921 - 148,364,097 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2154,861,345 - 154,959,674 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02152,910,789 - 153,009,122 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02147,543,478 - 147,641,810 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02154,256,382 - 154,468,166 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2154,256,380 - 154,418,920 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02173,640,220 - 173,849,566 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42153,467,156 - 153,562,651 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2142,435,231 - 142,522,875 (-)NCBICelera
Cytogenetic Map2q31NCBI
PLCH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383155,450,934 - 155,745,071 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3155,375,580 - 155,745,071 (-)EnsemblGRCh38hg38GRCh38
GRCh373155,197,670 - 155,462,860 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363156,680,365 - 156,796,861 (-)NCBINCBI36Build 36hg18NCBI36
Build 343156,680,372 - 156,796,869NCBI
Celera3153,618,259 - 153,842,073 (-)NCBICelera
Cytogenetic Map3q25.31NCBI
HuRef3152,592,070 - 152,816,187 (-)NCBIHuRef
CHM1_13155,160,735 - 155,385,162 (-)NCBICHM1_1
T2T-CHM13v2.03158,220,392 - 158,518,944 (-)NCBIT2T-CHM13v2.0
Plch1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39363,603,620 - 63,806,929 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl363,603,655 - 63,806,893 (-)EnsemblGRCm39 Ensembl
GRCm38363,696,199 - 63,899,503 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl363,696,234 - 63,899,472 (-)EnsemblGRCm38mm10GRCm38
MGSCv37363,500,156 - 63,654,913 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36363,784,166 - 63,938,968 (-)NCBIMGSCv36mm8
Celera363,363,083 - 63,521,241 (-)NCBICelera
Cytogenetic Map3E1NCBI
cM Map330.08NCBI
Plch1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554486,588,834 - 6,815,087 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554486,588,885 - 6,815,087 (-)NCBIChiLan1.0ChiLan1.0
PLCH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22153,389,975 - 153,659,937 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13153,394,705 - 153,664,656 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03152,530,928 - 152,800,963 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13160,484,462 - 160,853,113 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3160,583,085 - 160,784,611 (-)Ensemblpanpan1.1panPan2
PLCH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12349,280,314 - 49,483,210 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2349,281,620 - 49,450,050 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2349,155,971 - 49,359,036 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02349,915,081 - 50,116,886 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2349,914,938 - 50,055,473 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12349,500,267 - 49,704,229 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02349,549,504 - 49,752,859 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02349,834,268 - 50,037,303 (-)NCBIUU_Cfam_GSD_1.0
Plch1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560286,701,070 - 86,925,249 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365192,808,671 - 2,966,700 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365192,808,703 - 2,998,546 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1395,406,823 - 95,643,193 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11395,402,015 - 95,644,647 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213103,429,398 - 103,665,855 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLCH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11535,010,862 - 35,272,347 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660417,651,589 - 7,907,512 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plch1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473033,047,933 - 33,363,939 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473033,048,074 - 33,363,919 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plch1
904 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:110
Count of miRNA genes:95
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000057724
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)276539322150540526Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
8662836Vetf8Vascular elastic tissue fragility QTL 80.66thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2104559726149559726Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1354594Despr10Despair related QTL 100.00000249locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)2114654253159654253Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
5135226Leukc2Leukocyte quantity QTL 2eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)2118111229149559726Rat
1582257Gluco21Glucose level QTL 213.10.0035blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2118111229157142209Rat
738007Anxrr7Anxiety related response QTL 74.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2118189491163189491Rat
1358360Sradr2Stress Responsive Adrenal Weight QTL 210.24adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)2129164097152195315Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
1549828Bp258Blood pressure QTL 2580.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2142323368150650069Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
631520Bp73Blood pressure QTL 730.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147686913168355276Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat

Markers in Region
D2Got88  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22148,176,358 - 148,176,503 (+)MAPPERmRatBN7.2
Rnor_6.02154,283,645 - 154,283,789NCBIRnor6.0
Rnor_5.02173,667,483 - 173,667,627UniSTSRnor5.0
RGSC_v3.42153,494,426 - 153,494,571RGDRGSC3.4
RGSC_v3.42153,494,427 - 153,494,571UniSTSRGSC3.4
RGSC_v3.12153,444,390 - 153,444,534RGD
Celera2142,462,125 - 142,462,255UniSTS
RH 3.4 Map2947.9RGD
RH 3.4 Map2947.9UniSTS
Cytogenetic Map2q31UniSTS
AA892150  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22148,361,971 - 148,362,185 (+)MAPPERmRatBN7.2
Rnor_6.02154,466,534 - 154,466,747NCBIRnor6.0
Rnor_5.02173,850,372 - 173,850,585UniSTSRnor5.0
RGSC_v3.42153,687,648 - 153,687,861UniSTSRGSC3.4
Celera2142,644,169 - 142,644,382UniSTS
RH 3.4 Map2946.7UniSTS
Cytogenetic Map2q31UniSTS
AA892150  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22148,362,163 - 148,362,265 (+)MAPPERmRatBN7.2
Rnor_6.02154,466,726 - 154,466,827NCBIRnor6.0
Rnor_5.02173,850,564 - 173,850,665UniSTSRnor5.0
RGSC_v3.42153,687,840 - 153,687,941UniSTSRGSC3.4
Celera2142,644,361 - 142,644,462UniSTS
RH 3.4 Map2946.7UniSTS
Cytogenetic Map2q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43 12 4 4
Low 3 6 12 4 8 4 1 1 31 23 34 7 1
Below cutoff 19 18 10 10 10 6 7 3 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001191707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000057724   ⟹   ENSRNOP00000054535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2148,150,100 - 148,364,097 (-)Ensembl
Rnor_6.0 Ensembl2154,256,392 - 154,334,356 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076165   ⟹   ENSRNOP00000068291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2148,150,100 - 148,314,359 (-)Ensembl
Rnor_6.0 Ensembl2154,256,380 - 154,418,676 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076274   ⟹   ENSRNOP00000068287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2148,148,921 - 148,314,359 (-)Ensembl
Rnor_6.0 Ensembl2154,256,380 - 154,418,629 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076326   ⟹   ENSRNOP00000068040
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2148,149,436 - 148,314,359 (-)Ensembl
Rnor_6.0 Ensembl2154,256,393 - 154,418,920 (-)Ensembl
RefSeq Acc Id: NM_001191707   ⟹   NP_001178636
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,299,075 - 150,387,798 (-)NCBI
mRatBN7.22148,149,436 - 148,238,134 (-)NCBI
Rnor_6.02154,256,908 - 154,343,671 (-)NCBI
Rnor_5.02173,640,220 - 173,849,566 (-)NCBI
Celera2142,435,231 - 142,522,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102284   ⟹   XP_038958212
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,298,547 - 150,309,692 (-)NCBI
mRatBN7.22148,148,908 - 148,160,516 (-)NCBI
RefSeq Acc Id: XM_063281789   ⟹   XP_063137859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,298,547 - 150,510,956 (-)NCBI
RefSeq Acc Id: XM_063281790   ⟹   XP_063137860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,298,547 - 150,510,463 (-)NCBI
RefSeq Acc Id: XM_063281791   ⟹   XP_063137861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,298,547 - 150,514,120 (-)NCBI
RefSeq Acc Id: XM_063281792   ⟹   XP_063137862
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,298,547 - 150,510,956 (-)NCBI
RefSeq Acc Id: XM_063281793   ⟹   XP_063137863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,298,547 - 150,510,956 (-)NCBI
RefSeq Acc Id: XM_063281794   ⟹   XP_063137864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,298,547 - 150,464,286 (-)NCBI
RefSeq Acc Id: XM_063281795   ⟹   XP_063137865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,298,547 - 150,510,956 (-)NCBI
RefSeq Acc Id: XM_063281796   ⟹   XP_063137866
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,298,547 - 150,510,956 (-)NCBI
RefSeq Acc Id: XM_063281797   ⟹   XP_063137867
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,298,547 - 150,510,956 (-)NCBI
RefSeq Acc Id: XM_063281798   ⟹   XP_063137868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,301,624 - 150,510,956 (-)NCBI
RefSeq Acc Id: XM_063281799   ⟹   XP_063137869
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,301,624 - 150,510,956 (-)NCBI
RefSeq Acc Id: XM_063281800   ⟹   XP_063137870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,301,691 - 150,510,956 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001178636   ⟸   NM_001191707
- UniProtKB: A0A096MJ91 (UniProtKB/TrEMBL),   D4A4H0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000054535   ⟸   ENSRNOT00000057724
RefSeq Acc Id: ENSRNOP00000068287   ⟸   ENSRNOT00000076274
RefSeq Acc Id: ENSRNOP00000068040   ⟸   ENSRNOT00000076326
RefSeq Acc Id: ENSRNOP00000068291   ⟸   ENSRNOT00000076165
RefSeq Acc Id: XP_038958212   ⟸   XM_039102284
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063137861   ⟸   XM_063281791
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063137867   ⟸   XM_063281797
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063137866   ⟸   XM_063281796
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063137862   ⟸   XM_063281792
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063137865   ⟸   XM_063281795
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063137863   ⟸   XM_063281793
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063137859   ⟸   XM_063281789
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063137860   ⟸   XM_063281790
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063137864   ⟸   XM_063281794
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063137869   ⟸   XM_063281799
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063137868   ⟸   XM_063281798
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063137870   ⟸   XM_063281800
- Peptide Label: isoform X10
Protein Domains
C2   EF-hand   PH   PI-PLC Y-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A096MJW8-F1-model_v2 AlphaFold A0A096MJW8 1-1648 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561991 AgrOrtholog
BioCyc Gene G2FUF-52926 BioCyc
BioCyc Pathway PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis] BioCyc
  PWY-6367 [D-myo-inositol-5-phosphate metabolism] BioCyc
  PWY-8052 [2-arachidonoylglycerol biosynthesis] BioCyc
BioCyc Pathway Image PWY-6351 BioCyc
  PWY-6367 BioCyc
  PWY-8052 BioCyc
Ensembl Genes ENSRNOG00000009955 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057724.5 UniProtKB/TrEMBL
  ENSRNOT00000076165.3 UniProtKB/TrEMBL
  ENSRNOT00000076274.3 UniProtKB/TrEMBL
  ENSRNOT00000076326 ENTREZGENE
  ENSRNOT00000076326.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.20.20.190 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro C2_Ca-dep UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  Phospholipase_C_Pinositol-sp_Y UniProtKB/TrEMBL
  Pinositol_Phospholipase-C UniProtKB/TrEMBL
  PLC-eta1 UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  PLCeta1_EF UniProtKB/TrEMBL
  PLipase_C_EF-hand-like UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/TrEMBL
KEGG Report rno:310463 UniProtKB/TrEMBL
NCBI Gene 310463 ENTREZGENE
PANTHER PTHR10336 UniProtKB/TrEMBL
  PTHR10336:SF51 UniProtKB/TrEMBL
Pfam EF-hand_like UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PH_12 UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/TrEMBL
PhenoGen Plch1 PhenoGen
PRINTS PHPHLIPASEC UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PIPLC_X_DOMAIN UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009955 RatGTEx
SMART EFh UniProtKB/TrEMBL
  PLCXc UniProtKB/TrEMBL
  PLCYc UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
UniProt A0A096MJ91 ENTREZGENE, UniProtKB/TrEMBL
  A0A096MJW5_RAT UniProtKB/TrEMBL
  A0A096MJW8_RAT UniProtKB/TrEMBL
  D4A4H0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Plch1  phospholipase C, eta 1  Plcl3_predicted  phospholipase C-like 3 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Plcl3_predicted  phospholipase C-like 3 (predicted)  RGD1561991_predicted  similar to Hypothetical protein MGC57096 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1561991_predicted  similar to Hypothetical protein MGC57096 (predicted)  LOC310463  similar to Hypothetical protein MGC57096  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC310463  similar to Hypothetical protein MGC57096      Symbol and Name status set to provisional 70820 PROVISIONAL