Pramel38 (PRAME like 38) - Rat Genome Database

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Gene: Pramel38 (PRAME like 38) Rattus norvegicus
Analyze
Symbol: Pramel38 (Ensembl: RGD1561977)
Name: PRAME like 38 (Ensembl:similar to DNA segment, Chr 5, ERATO Doi 577, expressed)
RGD ID: 1561977
Description: Predicted to be involved in several processes, including negative regulation of DNA-templated transcription; negative regulation of apoptotic process; and positive regulation of cell population proliferation; INTERACTS WITH indole-3-methanol.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC501903; PRAME family member 8-like; RGD1561977; similar to DNA segment, Chr 5, ERATO Doi 577, expressed
RGD Orthologs
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81414,469,873 - 14,472,505 (+)NCBIGRCr8
mRatBN7.21414,165,928 - 14,168,560 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1414,165,928 - 14,168,560 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.014688,145 - 690,817 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.014691,238 - 693,870 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41415,969,610 - 15,972,242NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Pramel38
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81414,469,873 - 14,472,505 (+)NCBIGRCr8
mRatBN7.21414,165,928 - 14,168,560 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1414,165,928 - 14,168,560 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.014688,145 - 690,817 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.014691,238 - 693,870 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41415,969,610 - 15,972,242NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map14p22NCBI
Pramel38
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39594,308,261 - 94,368,952 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl594,304,436 - 94,369,394 (+)EnsemblGRCm39 Ensembl
GRCm38594,160,402 - 94,221,093 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl594,218,005 - 94,222,010 (+)EnsemblGRCm38mm10GRCm38
MGSCv37594,638,716 - 94,650,559 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36594,638,679 - 94,651,639 (+)NCBIMGSCv36mm8
Cytogenetic Map5E3NCBI
cM Map547.29NCBI

Variants

.
Variants in Pramel38
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:15
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000042604
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14121760616960180Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)14381307418274691Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14381307418274691Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14381307424531477Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062228035204Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141103081230320092Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000098433   ⟹   ENSRNOP00000086479
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1414,165,928 - 14,168,560 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119077   ⟹   ENSRNOP00000087954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1414,165,928 - 14,168,560 (+)Ensembl
RefSeq Acc Id: XM_008769912   ⟹   XP_008768134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81414,469,873 - 14,472,505 (+)NCBI
mRatBN7.21414,165,928 - 14,168,560 (+)NCBI
Rnor_6.014688,145 - 690,817 (+)NCBI
Sequence:
RefSeq Acc Id: XM_577327   ⟹   XP_577327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81414,469,873 - 14,472,505 (+)NCBI
mRatBN7.21414,165,928 - 14,168,560 (+)NCBI
Rnor_6.014688,145 - 690,817 (+)NCBI
Rnor_5.014691,238 - 693,870 (+)NCBI
RGSC_v3.41415,969,610 - 15,972,242 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs XP_008768134 (Get FASTA)   NCBI Sequence Viewer  
  XP_577327 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000086479
  ENSRNOP00000086479.1
  ENSRNOP00000087954
  ENSRNOP00000087954.1
Reference Protein Sequences
RefSeq Acc Id: XP_577327   ⟸   XM_577327
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A5E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768134   ⟸   XM_008769912
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A8Z8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000086479   ⟸   ENSRNOT00000098433
RefSeq Acc Id: ENSRNOP00000087954   ⟸   ENSRNOT00000119077

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-16300 BioCyc
Ensembl Genes ENSRNOG00000063585 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000098433 ENTREZGENE
  ENSRNOT00000098433.1 UniProtKB/TrEMBL
  ENSRNOT00000119077 ENTREZGENE
  ENSRNOT00000119077.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro LRR_dom_sf UniProtKB/TrEMBL
  PRAME_family UniProtKB/TrEMBL
KEGG Report rno:501903 UniProtKB/TrEMBL
NCBI Gene 501903 ENTREZGENE
PANTHER D5ERTD577E PROTEIN-RELATED UniProtKB/TrEMBL
  SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 UniProtKB/TrEMBL
PhenoGen Pramel38 PhenoGen
PIRSF PRAME UniProtKB/TrEMBL
RatGTEx ENSRNOG00000063585 RatGTEx
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
UniProt A0A8I6A5E7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8Z8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-03-14 Pramel38  PRAME like 38  RGD1561977  similar to DNA segment, Chr 5, ERATO Doi 577, expressed  Name and Symbol changed 629549 APPROVED
2022-06-02 RGD1561977  similar to DNA segment, Chr 5, ERATO Doi 577, expressed  RGD1561977  similar to DNA segment, Chr 5, ERATO Doi 577, expressed  Data merged from RGD:149736211 737654 PROVISIONAL
2021-08-09 RGD1561977  similar to DNA segment, Chr 5, ERATO Doi 577, expressed      Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 RGD1561977  similar to DNA segment, Chr 5, ERATO Doi 577, expressed   RGD1561977_predicted  similar to DNA segment, Chr 5, ERATO Doi 577, expressed (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561977_predicted  similar to DNA segment, Chr 5, ERATO Doi 577, expressed (predicted)  LOC501903  similar to DNA segment, Chr 5, ERATO Doi 577, expressed  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501903  similar to DNA segment, Chr 5, ERATO Doi 577, expressed      Symbol and Name status set to provisional 70820 PROVISIONAL