Rps18l2 (ribosomal protein S18 like 2) - Rat Genome Database

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Pathways
Gene: Rps18l2 (ribosomal protein S18 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps18l2
Name: ribosomal protein S18 like 2
RGD ID: 1561919
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of small ribosomal subunit. Predicted to be active in cytosol. Orthologous to human RPS18 (ribosomal protein S18); INTERACTS WITH indole-3-methanol; rotenone.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 40S ribosomal protein S18-like; LOC307665; RGD1561919; ribosomal protein S18-like; similar to ribosomal protein S18; small ribosomal subunit protein uS13-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81913,112,901 - 13,113,399 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1913,112,901 - 13,113,359 (+)EnsemblGRCr8
mRatBN7.21913,107,145 - 13,107,646 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1913,107,145 - 13,107,603 (+)EnsemblmRatBN7.2
Rnor_6.01914,093,225 - 14,093,723 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01925,205,940 - 25,206,438 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41913,615,405 - 13,615,905 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1912,971,190 - 12,980,562 (+)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
translation  (IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rps18l2
4 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:129
Count of miRNA genes:118
Interacting mature miRNAs:124
Transcripts:ENSRNOT00000047417
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131969901Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127361636Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124694445Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
40 24 118 165 498 108 246 7 82 128 82 25 775 443 97 483 1 241 142 167 25 25

Sequence


Ensembl Acc Id: ENSRNOT00000047417   ⟹   ENSRNOP00000040056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1913,112,901 - 13,113,359 (+)Ensembl
RefSeq Acc Id: XM_039098133   ⟹   XP_038954061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81913,112,901 - 13,113,399 (+)NCBI
mRatBN7.21913,107,145 - 13,107,646 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038954061 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040056
  ENSRNOP00000040056.2
  ENSRNOP00000075857.4
RefSeq Acc Id: XP_038954061   ⟸   XM_039098133
- UniProtKB: D3ZAU6 (UniProtKB/TrEMBL),   A0A8L2URK8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000040056   ⟸   ENSRNOT00000047417

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAU6-F1-model_v2 AlphaFold D3ZAU6 1-152 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561919 AgrOrtholog
BioCyc Gene G2FUF-6439 BioCyc
Ensembl Genes ENSRNOG00000000471 UniProtKB/TrEMBL
  ENSRNOG00000033451 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047417 ENTREZGENE
  ENSRNOT00000047417.5 UniProtKB/TrEMBL
  ENSRNOT00000092476.4 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.50 UniProtKB/TrEMBL
  4.10.910.10 UniProtKB/TrEMBL
InterPro 30s_Rbsml_prot_S13_C UniProtKB/TrEMBL
  Ribosomal_S13 UniProtKB/TrEMBL
  Ribosomal_S13-like_H2TH UniProtKB/TrEMBL
  Ribosomal_uS13_CS UniProtKB/TrEMBL
KEGG Report rno:307665 UniProtKB/TrEMBL
NCBI Gene 307665 ENTREZGENE
PANTHER 30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18 UniProtKB/TrEMBL
  SMALL RIBOSOMAL SUBUNIT PROTEIN US13 UniProtKB/TrEMBL
  SMALL RIBOSOMAL SUBUNIT PROTEIN US13 UniProtKB/TrEMBL
Pfam Ribosomal_S13 UniProtKB/TrEMBL
PhenoGen Rps18l2 PhenoGen
PIRSF Ribosomal_S13 UniProtKB/TrEMBL
PROSITE RIBOSOMAL_S13_1 UniProtKB/TrEMBL
  RIBOSOMAL_S13_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000471 RatGTEx
  ENSRNOG00000033451 RatGTEx
Superfamily-SCOP SSF46946 UniProtKB/TrEMBL
UniProt A0A8L2URK8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZAU6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rps18l2  ribosomal protein S18 like 2  RGD1561919  similar to ribosomal protein S18  Symbol and Name Changed 1299863 APPROVED
2013-05-24 RGD1561919  similar to ribosomal protein S18  LOC100363954  ribosomal protein S18-like  Data merged from RGD:2322003 1643240 APPROVED
2010-05-06 LOC100363954  ribosomal protein S18-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1561919  similar to ribosomal protein S18   RGD1561919_predicted  similar to ribosomal protein S18 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561919_predicted  similar to ribosomal protein S18 (predicted)  LOC307665  similar to ribosomal protein S18  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC307665  similar to ribosomal protein S18      Symbol and Name status set to provisional 70820 PROVISIONAL