Ctag2 (cancer/testis antigen 2) - Rat Genome Database

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Gene: Ctag2 (cancer/testis antigen 2) Rattus norvegicus
Analyze
Symbol: Ctag2
Name: cancer/testis antigen 2
RGD ID: 1561702
Description: Predicted to be involved in tRNA threonylcarbamoyladenosine metabolic process. Predicted to be located in centrosome. Predicted to be part of EKC/KEOPS complex. Orthologous to human CTAG2 (cancer/testis antigen 2); INTERACTS WITH bisphenol A; 5-aza-2'-deoxycytidine (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC501655; RGD1561702; similar to ESO3 protein
RGD Orthologs
Human
Mouse
Dog
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X148,567,674 - 148,568,972 (+)NCBIGRCr8
mRatBN7.2X143,531,907 - 143,533,201 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX143,531,907 - 143,533,201 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX145,726,940 - 145,728,234 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X149,251,924 - 149,253,218 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X146,801,531 - 146,802,825 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X148,421,627 - 148,422,921 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX148,421,627 - 148,422,921 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X148,434,846 - 148,436,140 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X150,890,416 - 150,891,710 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX139,402,108 - 139,403,402 (+)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Ctag2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X148,567,674 - 148,568,972 (+)NCBIGRCr8
mRatBN7.2X143,531,907 - 143,533,201 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX143,531,907 - 143,533,201 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX145,726,940 - 145,728,234 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X149,251,924 - 149,253,218 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X146,801,531 - 146,802,825 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X148,421,627 - 148,422,921 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX148,421,627 - 148,422,921 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X148,434,846 - 148,436,140 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X150,890,416 - 150,891,710 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX139,402,108 - 139,403,402 (+)NCBICelera
Cytogenetic MapXq36NCBI
CTAG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,651,977 - 154,653,579 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX154,651,972 - 154,653,579 (-)EnsemblGRCh38hg38GRCh38
GRCh37X153,880,251 - 153,881,853 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,533,445 - 153,535,036 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X153,443,955 - 153,445,545NCBI
CeleraX154,038,327 - 154,039,934 (-)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,424,869 - 142,426,195 (-)NCBIHuRef
CHM1_1X153,791,956 - 153,793,563 (-)NCBICHM1_1
T2T-CHM13v2.0X152,888,418 - 152,890,020 (-)NCBIT2T-CHM13v2.0
Ctag2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X64,091,250 - 64,092,623 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX64,091,250 - 64,092,620 (+)EnsemblGRCm39 Ensembl
GRCm38X65,047,644 - 65,049,017 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX65,047,644 - 65,049,014 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X62,300,819 - 62,302,192 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X61,308,315 - 61,309,679 (+)NCBIMGSCv36mm8
CeleraX51,444,062 - 51,445,435 (+)NCBICelera
Cytogenetic MapXA7.1NCBI
cM MapX34.64NCBI
LOC100683646
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,566,522 - 122,567,799 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX107,574,944 - 107,576,223 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X125,773,906 - 125,775,187 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X121,541,050 - 121,542,330 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X124,056,237 - 124,057,518 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X123,822,335 - 123,823,616 (+)NCBIUU_Cfam_GSD_1.0
LOC103232838
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X128,864,043 - 128,868,405 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366634444,769 - 47,277 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Ctag2
1 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:92
Count of miRNA genes:83
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000016754
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system integumental system musculoskeletal system nervous system reproductive system appendage
High
Medium 7
Low 1
Below cutoff 1 3 3 2 2 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000016754   ⟹   ENSRNOP00000016754
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX143,531,907 - 143,533,201 (+)Ensembl
Rnor_6.0 EnsemblX148,421,627 - 148,422,921 (+)Ensembl
RefSeq Acc Id: NM_001109322   ⟹   NP_001102792
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X148,567,674 - 148,568,968 (+)NCBI
mRatBN7.2X143,531,907 - 143,533,201 (+)NCBI
Rnor_6.0X148,421,627 - 148,422,921 (+)NCBI
Rnor_5.0X148,434,846 - 148,436,140 (+)NCBI
RGSC_v3.4X150,890,416 - 150,891,710 (+)RGD
CeleraX139,402,108 - 139,403,402 (+)RGD
Sequence:
RefSeq Acc Id: XM_063280258   ⟹   XP_063136328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X148,567,677 - 148,568,972 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102792 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136328 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL86187 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016754
  ENSRNOP00000016754.3
Reference Protein Sequences
RefSeq Acc Id: NP_001102792   ⟸   NM_001109322
- UniProtKB: D3ZZR7 (UniProtKB/TrEMBL),   A6K519 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016754   ⟸   ENSRNOT00000016754
RefSeq Acc Id: XP_063136328   ⟸   XM_063280258
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZR7-F1-model_v2 AlphaFold D3ZZR7 1-199 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702026
Promoter ID:EPDNEW_R12548
Type:single initiation site
Name:Ctag2_1
Description:cancer/testis antigen 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X148,421,660 - 148,421,720EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561702 AgrOrtholog
BioCyc Gene G2FUF-836 BioCyc
Ensembl Genes ENSRNOG00000012560 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016754 ENTREZGENE
  ENSRNOT00000016754.4 UniProtKB/TrEMBL
Gene3D-CATH Alpha-D-phosphohexomutase, C-terminal domain UniProtKB/TrEMBL
InterPro EKC/KEOPS_Pcc1 UniProtKB/TrEMBL
KEGG Report rno:501655 UniProtKB/TrEMBL
NCBI Gene 501655 ENTREZGENE
PANTHER CANCER/TESTIS ANTIGEN 2 UniProtKB/TrEMBL
  PTHR31283 UniProtKB/TrEMBL
Pfam Pcc1 UniProtKB/TrEMBL
PhenoGen Ctag2 PhenoGen
RatGTEx ENSRNOG00000012560 RatGTEx
UniProt A6K519 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZR7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-29 Ctag2  cancer/testis antigen 2  RGD1561702_predicted  similar to ESO3 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1561702_predicted  similar to ESO3 protein (predicted)  LOC501655  similar to ESO3 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501655  similar to ESO3 protein      Symbol and Name status set to provisional 70820 PROVISIONAL