Magec2l1 (MAGE family member C2 like 1) - Rat Genome Database

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Gene: Magec2l1 (MAGE family member C2 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Magec2l1 (Ensembl: RGD1561327)
Name: MAGE family member C2 like 1 (Ensembl:similar to melanoma antigen family A, 10)
RGD ID: 1561327
Description: Orthologous to human MAGEC1 (MAGE family member C1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; gentamycin; trichloroethene.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC317593; melanoma-associated antigen 1-like; RGD1561327; similar to melanoma antigen family A, 10
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X144,565,315 - 144,746,908 (+)NCBIGRCr8
mRatBN7.2X139,529,048 - 139,710,648 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX139,531,708 - 139,710,660 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X144,257,983 - 144,447,709 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX144,445,795 - 144,447,447 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X144,282,261 - 144,473,138 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X146,924,251 - 146,928,236 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX135,577,543 - 135,749,105 (+)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Magec2l1
666 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:165
Count of miRNA genes:130
Interacting mature miRNAs:144
Transcripts:ENSRNOT00000048467
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat

Markers in Region
AU022494  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X139,680,514 - 139,680,732 (+)MAPPERmRatBN7.2
mRatBN7.21220,643,310 - 20,643,528 (-)MAPPERmRatBN7.2
Rnor_6.0X144,418,927 - 144,419,144NCBIRnor6.0
Rnor_5.0X144,444,138 - 144,444,355UniSTSRnor5.0
RGSC_v3.4X146,898,383 - 146,898,600UniSTSRGSC3.4
CeleraX135,724,984 - 135,725,201UniSTS
Cytogenetic MapXq36UniSTS
Cytogenetic Map12q12UniSTS
AA851932  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X139,710,205 - 139,710,318 (+)MAPPERmRatBN7.2
Rnor_6.0X144,447,215 - 144,447,327NCBIRnor6.0
Rnor_5.0X144,472,787 - 144,472,899UniSTSRnor5.0
RGSC_v3.4X146,927,885 - 146,927,997UniSTSRGSC3.4
CeleraX135,748,611 - 135,748,723UniSTS
Cytogenetic MapXq36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 33 3
Low 31 17 7
Below cutoff 3 1 15 7 3 7 4 4 6 11 13 4 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_017588346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010061285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010061286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_589817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_597800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_597802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_597803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_597804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000048467   ⟹   ENSRNOP00000039887
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX139,703,685 - 139,710,660 (+)Ensembl
Rnor_6.0 EnsemblX144,445,795 - 144,447,447 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118256   ⟹   ENSRNOP00000081630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX139,546,514 - 139,710,660 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118327   ⟹   ENSRNOP00000093522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX139,531,708 - 139,710,660 (+)Ensembl
RefSeq Acc Id: XM_017602412   ⟹   XP_017457901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,565,315 - 144,746,908 (+)NCBI
mRatBN7.2X139,529,048 - 139,710,648 (+)NCBI
Rnor_6.0X144,257,983 - 144,447,709 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017602413   ⟹   XP_017457902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,571,558 - 144,746,908 (+)NCBI
mRatBN7.2X139,535,291 - 139,710,648 (+)NCBI
Rnor_6.0X144,276,886 - 144,447,709 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039100415   ⟹   XP_038956343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,565,315 - 144,746,908 (+)NCBI
mRatBN7.2X139,529,048 - 139,710,648 (+)NCBI
RefSeq Acc Id: XM_039100416   ⟹   XP_038956344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,565,315 - 144,746,908 (+)NCBI
mRatBN7.2X139,529,048 - 139,710,648 (+)NCBI
RefSeq Acc Id: XM_039100417   ⟹   XP_038956345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,565,315 - 144,746,908 (+)NCBI
mRatBN7.2X139,529,048 - 139,710,648 (+)NCBI
RefSeq Acc Id: XM_039100419   ⟹   XP_038956347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,565,315 - 144,746,908 (+)NCBI
mRatBN7.2X139,529,048 - 139,710,648 (+)NCBI
RefSeq Acc Id: XM_039100420   ⟹   XP_038956348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,571,558 - 144,746,908 (+)NCBI
mRatBN7.2X139,535,291 - 139,710,648 (+)NCBI
RefSeq Acc Id: XM_063280355   ⟹   XP_063136425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,565,315 - 144,746,908 (+)NCBI
RefSeq Acc Id: XM_063280356   ⟹   XP_063136426
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,565,315 - 144,746,908 (+)NCBI
RefSeq Acc Id: XM_063280357   ⟹   XP_063136427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,567,665 - 144,746,908 (+)NCBI
RefSeq Acc Id: XM_063280358   ⟹   XP_063136428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,738,204 - 144,746,908 (+)NCBI
RefSeq Acc Id: XR_010061285
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,565,315 - 144,617,564 (+)NCBI
RefSeq Acc Id: XR_010061286
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X144,565,315 - 144,617,641 (+)NCBI
RefSeq Acc Id: XP_017457901   ⟸   XM_017602412
- UniProtKB: F1LUV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457902   ⟸   XM_017602413
- UniProtKB: F1LUV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000039887   ⟸   ENSRNOT00000048467
RefSeq Acc Id: XP_038956343   ⟸   XM_039100415
- UniProtKB: F1LUV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956344   ⟸   XM_039100416
- UniProtKB: F1LUV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956345   ⟸   XM_039100417
- UniProtKB: F1LUV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956347   ⟸   XM_039100419
- UniProtKB: F1LUV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038956348   ⟸   XM_039100420
- UniProtKB: F1LUV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000093522   ⟸   ENSRNOT00000118327
RefSeq Acc Id: ENSRNOP00000081630   ⟸   ENSRNOT00000118256
RefSeq Acc Id: XP_063136425   ⟸   XM_063280355
RefSeq Acc Id: XP_063136426   ⟸   XM_063280356
RefSeq Acc Id: XP_063136427   ⟸   XM_063280357
RefSeq Acc Id: XP_063136428   ⟸   XM_063280358
Protein Domains
MAGE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LUV1-F1-model_v2 AlphaFold F1LUV1 1-419 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561327 AgrOrtholog
BioCyc Gene G2FUF-867 BioCyc
Ensembl Genes ENSRNOG00000031222 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048467.4 UniProtKB/TrEMBL
  ENSRNOT00000118256.1 UniProtKB/TrEMBL
  ENSRNOT00000118327.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
  MHD_dom UniProtKB/TrEMBL
KEGG Report rno:317593 UniProtKB/TrEMBL
NCBI Gene 317593 ENTREZGENE
PANTHER MELANOMA-ASSOCIATED ANTIGEN C2 UniProtKB/TrEMBL
  PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
PhenoGen Magec2l1 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031222 RatGTEx
SMART MAGE UniProtKB/TrEMBL
UniProt F1LUV1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Magec2l1  MAGE family member C2 like 1  RGD1561327  similar to melanoma antigen family A, 10  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1561327  similar to melanoma antigen family A, 10   RGD1561327_predicted  similar to melanoma antigen family A, 10 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561327_predicted  similar to melanoma antigen family A, 10 (predicted)  LOC317593  similar to melanoma antigen family A, 10  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317593  similar to melanoma antigen family A, 10      Symbol and Name status set to provisional 70820 PROVISIONAL