Mdm1 (Mdm1 nuclear protein) - Rat Genome Database

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Gene: Mdm1 (Mdm1 nuclear protein) Rattus norvegicus
Analyze
Symbol: Mdm1
Name: Mdm1 nuclear protein
RGD ID: 1561092
Description: Predicted to enable microtubule binding activity. Predicted to be involved in negative regulation of centriole replication and retina development in camera-type eye. Predicted to act upstream of or within photoreceptor cell maintenance. Predicted to be located in several cellular components, including cytosol; microtubule organizing center; and non-motile cilium. Orthologous to human MDM1 (Mdm1 nuclear protein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC314859; Mdm1 nuclear protein homolog; Mdm1 nuclear protein homolog (mouse); nuclear protein MDM1; similar to transformed mouse 3T3 cell double minute 1; transformed mouse 3T3 cell double minute 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8755,615,459 - 55,651,889 (+)NCBIGRCr8
mRatBN7.2753,729,603 - 53,766,034 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl753,729,610 - 53,766,034 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx755,646,237 - 55,672,740 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0757,849,342 - 57,875,845 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0757,627,185 - 57,653,689 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0761,165,652 - 61,200,865 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl761,165,640 - 61,200,879 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0761,161,294 - 61,197,124 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4757,455,598 - 57,482,092 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera750,507,908 - 50,534,254 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centriolar satellite  (ISO)
centriole  (ISO,ISS)
centrosome  (IEA,ISO,ISS)
cytoplasm  (IEA)
cytosol  (ISO)
microtubule  (IEA)
non-motile cilium  (ISO)
nucleus  (IEA,ISO,ISS)

Molecular Function
microtubule binding  (IEA,ISO,ISS)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Age-related retinal degeneration (arrd2) in a novel mouse model due to a nonsense mutation in the Mdm1 gene. Chang B, etal., Hum Mol Genet. 2008 Dec 15;17(24):3929-41. doi: 10.1093/hmg/ddn295. Epub 2008 Sep 18.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:21052544   PMID:23300604   PMID:26337392  


Genomics

Comparative Map Data
Mdm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8755,615,459 - 55,651,889 (+)NCBIGRCr8
mRatBN7.2753,729,603 - 53,766,034 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl753,729,610 - 53,766,034 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx755,646,237 - 55,672,740 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0757,849,342 - 57,875,845 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0757,627,185 - 57,653,689 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0761,165,652 - 61,200,865 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl761,165,640 - 61,200,879 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0761,161,294 - 61,197,124 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4757,455,598 - 57,482,092 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera750,507,908 - 50,534,254 (+)NCBICelera
Cytogenetic Map7q22NCBI
MDM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381268,294,566 - 68,332,362 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1268,272,443 - 68,332,381 (-)EnsemblGRCh38hg38GRCh38
GRCh371268,688,346 - 68,726,142 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361266,974,613 - 67,012,379 (-)NCBINCBI36Build 36hg18NCBI36
Build 341267,005,167 - 67,012,350NCBI
Celera1268,352,374 - 68,390,189 (-)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1265,739,499 - 65,777,306 (-)NCBIHuRef
CHM1_11268,656,328 - 68,694,144 (-)NCBICHM1_1
T2T-CHM13v2.01268,274,117 - 68,311,913 (-)NCBIT2T-CHM13v2.0
Mdm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910117,977,446 - 118,004,904 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10117,977,716 - 118,004,902 (+)EnsemblGRCm39 Ensembl
GRCm3810118,141,540 - 118,168,999 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10118,141,811 - 118,168,997 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710117,578,843 - 117,606,055 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610117,544,825 - 117,571,990 (+)NCBIMGSCv36mm8
Celera10120,092,487 - 120,120,063 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1066.65NCBI
Mdm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545814,780,437 - 14,822,954 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545814,789,842 - 14,823,117 (-)NCBIChiLan1.0ChiLan1.0
MDM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21076,310,352 - 76,348,641 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11276,306,749 - 76,345,038 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01265,803,548 - 65,841,404 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11268,588,541 - 68,626,359 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1268,588,541 - 68,626,326 (-)Ensemblpanpan1.1panPan2
MDM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11010,523,656 - 10,552,824 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1010,524,328 - 10,696,181 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1010,456,983 - 10,486,143 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01010,647,765 - 10,676,917 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1010,647,770 - 10,676,899 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11010,515,759 - 10,544,917 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01010,762,218 - 10,791,382 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01010,884,769 - 10,913,942 (-)NCBIUU_Cfam_GSD_1.0
Mdm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494547,815,517 - 47,848,237 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365456,261,875 - 6,294,621 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365456,261,887 - 6,294,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MDM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl532,640,945 - 32,673,638 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1532,640,939 - 32,673,624 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2535,453,845 - 35,486,488 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MDM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11163,926,950 - 64,082,149 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1163,927,640 - 63,965,097 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037181,740,938 - 181,779,219 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mdm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248022,648 - 9,999 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mdm1
130 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:159
Count of miRNA genes:110
Interacting mature miRNAs:140
Transcripts:ENSRNOT00000048765
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat

Markers in Region
RH136966  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2753,765,803 - 53,765,963 (+)MAPPERmRatBN7.2
Rnor_6.0761,200,635 - 61,200,794NCBIRnor6.0
Rnor_5.0761,196,894 - 61,197,053UniSTSRnor5.0
RGSC_v3.4757,481,862 - 57,482,021UniSTSRGSC3.4
Celera750,534,024 - 50,534,183UniSTS
RH 3.4 Map7482.2UniSTS
Cytogenetic Map7q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 24 27 18 15 18 63 21 41 11
Low 2 19 30 23 4 23 8 11 11 14 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001017459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC087101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB544747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV126474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000048765   ⟹   ENSRNOP00000041359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl753,739,532 - 53,766,032 (+)Ensembl
Rnor_6.0 Ensembl761,174,369 - 61,200,863 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087955   ⟹   ENSRNOP00000075623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl753,729,610 - 53,766,034 (+)Ensembl
Rnor_6.0 Ensembl761,165,640 - 61,200,879 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091885   ⟹   ENSRNOP00000071496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl753,739,532 - 53,766,032 (+)Ensembl
Rnor_6.0 Ensembl761,174,401 - 61,200,863 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108196   ⟹   ENSRNOP00000091573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl753,739,532 - 53,765,210 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114732   ⟹   ENSRNOP00000077918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl753,739,532 - 53,745,080 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118906   ⟹   ENSRNOP00000081317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl753,739,265 - 53,766,034 (+)Ensembl
RefSeq Acc Id: NM_001017459   ⟹   NP_001017459
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,625,388 - 55,651,889 (+)NCBI
mRatBN7.2753,739,532 - 53,766,034 (+)NCBI
Rnor_6.0761,174,369 - 61,200,865 (+)NCBI
Rnor_5.0761,161,294 - 61,197,124 (+)NCBI
RGSC_v3.4757,455,598 - 57,482,092 (+)RGD
Celera750,507,908 - 50,534,254 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241385   ⟹   XP_006241447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,625,364 - 55,651,889 (+)NCBI
mRatBN7.2753,739,500 - 53,766,034 (+)NCBI
Rnor_6.0761,174,340 - 61,200,865 (+)NCBI
Rnor_5.0761,161,294 - 61,197,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241387   ⟹   XP_006241449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,624,837 - 55,651,889 (+)NCBI
mRatBN7.2753,739,280 - 53,766,034 (+)NCBI
Rnor_6.0761,174,158 - 61,200,865 (+)NCBI
Rnor_5.0761,161,294 - 61,197,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241388   ⟹   XP_006241450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,625,365 - 55,651,889 (+)NCBI
mRatBN7.2753,739,502 - 53,766,034 (+)NCBI
Rnor_6.0761,174,340 - 61,200,865 (+)NCBI
Rnor_5.0761,161,294 - 61,197,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008765400   ⟹   XP_008763622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,459 - 55,651,889 (+)NCBI
mRatBN7.2753,729,603 - 53,766,034 (+)NCBI
Rnor_6.0761,165,652 - 61,200,865 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079129   ⟹   XP_038935057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,634,195 - 55,651,889 (+)NCBI
mRatBN7.2753,749,240 - 53,766,034 (+)NCBI
RefSeq Acc Id: XM_063263489   ⟹   XP_063119559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,485 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263490   ⟹   XP_063119560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,625,364 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263491   ⟹   XP_063119561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,485 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263492   ⟹   XP_063119562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,459 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263493   ⟹   XP_063119563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,624,837 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263494   ⟹   XP_063119564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,485 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263495   ⟹   XP_063119565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,624,837 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263496   ⟹   XP_063119566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,485 - 55,651,889 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001017459   ⟸   NM_001017459
- UniProtKB: Q5PQN4 (UniProtKB/Swiss-Prot),   A0A0G2KB24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241449   ⟸   XM_006241387
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZUT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241447   ⟸   XM_006241385
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KB24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241450   ⟸   XM_006241388
- Peptide Label: isoform X4
- UniProtKB: A6IGU6 (UniProtKB/TrEMBL),   A0A0G2KB24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763622   ⟸   XM_008765400
- Peptide Label: isoform X2
- UniProtKB: A0A0G2KB24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075623   ⟸   ENSRNOT00000087955
RefSeq Acc Id: ENSRNOP00000041359   ⟸   ENSRNOT00000048765
RefSeq Acc Id: ENSRNOP00000071496   ⟸   ENSRNOT00000091885
RefSeq Acc Id: XP_038935057   ⟸   XM_039079129
- Peptide Label: isoform X11
RefSeq Acc Id: ENSRNOP00000081317   ⟸   ENSRNOT00000118906
RefSeq Acc Id: ENSRNOP00000091573   ⟸   ENSRNOT00000108196
RefSeq Acc Id: ENSRNOP00000077918   ⟸   ENSRNOT00000114732
RefSeq Acc Id: XP_063119562   ⟸   XM_063263492
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063119566   ⟸   XM_063263496
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063119559   ⟸   XM_063263489
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063119561   ⟸   XM_063263491
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063119564   ⟸   XM_063263494
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063119563   ⟸   XM_063263493
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063119565   ⟸   XM_063263495
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063119560   ⟸   XM_063263490
- Peptide Label: isoform X5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PQN4-F1-model_v2 AlphaFold Q5PQN4 1-719 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695225
Promoter ID:EPDNEW_R5744
Type:initiation region
Name:Mdm1_1
Description:Mdm1 nuclear protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0761,174,446 - 61,174,506EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561092 AgrOrtholog
BioCyc Gene G2FUF-33945 BioCyc
Ensembl Genes ENSRNOG00000007286 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055012288 UniProtKB/Swiss-Prot
  ENSRNOG00060008292 UniProtKB/Swiss-Prot
  ENSRNOG00065013049 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000048765 ENTREZGENE
  ENSRNOT00000048765.6 UniProtKB/Swiss-Prot
  ENSRNOT00000087955.2 UniProtKB/TrEMBL
  ENSRNOT00000091885.2 UniProtKB/TrEMBL
  ENSRNOT00000108196.1 UniProtKB/TrEMBL
  ENSRNOT00000114732.1 UniProtKB/TrEMBL
  ENSRNOT00000118906.1 UniProtKB/TrEMBL
  ENSRNOT00055020927 UniProtKB/Swiss-Prot
  ENSRNOT00060013983 UniProtKB/Swiss-Prot
  ENSRNOT00065021494 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7192579 IMAGE-MGC_LOAD
InterPro MDM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:314859 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94684 IMAGE-MGC_LOAD
NCBI Gene 314859 ENTREZGENE
PANTHER NUCLEAR PROTEIN MDM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR32078 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MDM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mdm1 PhenoGen
RatGTEx ENSRNOG00000007286 RatGTEx
  ENSRNOG00055012288 RatGTEx
  ENSRNOG00060008292 RatGTEx
  ENSRNOG00065013049 RatGTEx
UniProt A0A0G2K0L7_RAT UniProtKB/TrEMBL
  A0A0G2KB24 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5YCK2_RAT UniProtKB/TrEMBL
  A0A8I5ZUT4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJR7_RAT UniProtKB/TrEMBL
  A6IGU6 ENTREZGENE, UniProtKB/TrEMBL
  MDM1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-26 Mdm1  Mdm1 nuclear protein  Mdm1  Mdm1 nuclear protein homolog (mouse)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-24 Mdm1  Mdm1 nuclear protein homolog (mouse)  Mdm1  transformed mouse 3T3 cell double minute 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Mdm1  transformed mouse 3T3 cell double minute 1  LOC314859  similar to transformed mouse 3T3 cell double minute 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC314859  similar to transformed mouse 3T3 cell double minute 1      Symbol and Name status set to provisional 70820 PROVISIONAL