Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Pced1b (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PCED1B mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | increases expression | ISO | Pced1b (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PCED1B mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | PCED1B (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of PCED1B mRNA | CTD | PMID:30165855 | 17beta-estradiol | decreases expression | ISO | PCED1B (Homo sapiens) | 6480464 | Estradiol results in decreased expression of PCED1B mRNA | CTD | PMID:31614463 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Pced1b (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Pced1b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PCED1B mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PCED1B mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pced1b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PCED1B mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | PCED1B (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PCED1B mRNA | CTD | PMID:22298810 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PCED1B mRNA | CTD | PMID:24780913 | afimoxifene | multiple interactions | ISO | PCED1B (Homo sapiens) | 6480464 | afimoxifene inhibits the reaction [Estrogens results in decreased expression of PCED1B mRNA] | CTD | PMID:21233418 | all-trans-retinoic acid | increases expression | ISO | PCED1B (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PCED1B mRNA | CTD | PMID:23830798 | antirheumatic drug | decreases expression | ISO | PCED1B (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of PCED1B mRNA | CTD | PMID:24449571 | arsane | affects methylation | ISO | PCED1B (Homo sapiens) | 6480464 | Arsenic affects the methylation of PCED1B gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | PCED1B (Homo sapiens) | 6480464 | Arsenic affects the methylation of PCED1B gene | CTD | PMID:25304211 | benzo[a]pyrene | affects methylation | ISO | Pced1b (Mus musculus) | 6480464 | Benzo(a)pyrene affects the methylation of PCED1B intron | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | PCED1B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PCED1B 5' UTR | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PCED1B mRNA | CTD | PMID:25181051 | bisphenol A | decreases methylation | ISO | PCED1B (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of PCED1B gene | CTD | PMID:31601247 | buta-1,3-diene | decreases expression | ISO | Pced1b (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of PCED1B mRNA | CTD | PMID:29038090 | butanal | decreases expression | ISO | PCED1B (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of PCED1B mRNA | CTD | PMID:26079696 | carbon nanotube | decreases expression | ISO | Pced1b (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cytarabine | decreases expression | ISO | PCED1B (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of PCED1B mRNA | CTD | PMID:21198554 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of PCED1B mRNA | CTD | PMID:21266533 | dimethylarsinic acid | multiple interactions | ISO | Pced1b (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of PCED1B mRNA | CTD | PMID:34876320 | folic acid | multiple interactions | ISO | Pced1b (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PCED1B mRNA | CTD | PMID:22206623 | fonofos | decreases methylation | ISO | PCED1B (Homo sapiens) | 6480464 | Fonofos results in decreased methylation of PCED1B promoter | CTD | PMID:22847954 | formaldehyde | decreases expression | ISO | PCED1B (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of PCED1B mRNA | CTD | PMID:23649840 | formaldehyde | increases expression | ISO | PCED1B (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of PCED1B mRNA | CTD | PMID:27664576 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of PCED1B mRNA | CTD | PMID:33387578 | lipopolysaccharide | multiple interactions | ISO | PCED1B (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of PCED1B mRNA | CTD | PMID:35811015 | methylarsonic acid | multiple interactions | ISO | Pced1b (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of PCED1B mRNA | CTD | PMID:34876320 | mono(2-ethylhexyl) phthalate | increases expression | ISO | PCED1B (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of PCED1B mRNA | CTD | PMID:36695872 | nickel atom | increases expression | ISO | PCED1B (Homo sapiens) | 6480464 | Nickel results in increased expression of PCED1B mRNA | CTD | PMID:24768652 and PMID:25583101 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PCED1B mRNA | CTD | PMID:33387578 | parathion | decreases methylation | ISO | PCED1B (Homo sapiens) | 6480464 | Parathion results in decreased methylation of PCED1B promoter | CTD | PMID:22847954 | pirinixic acid | multiple interactions | ISO | PCED1B (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PCED1B mRNA | CTD | PMID:19710929 | pirinixic acid | multiple interactions | ISO | Pced1b (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PCED1B mRNA | CTD | PMID:19710929 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | PCED1B (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of PCED1B mRNA | CTD | PMID:35811015 | sodium arsenate | multiple interactions | ISO | Pced1b (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of PCED1B mRNA | CTD | PMID:34876320 | sodium arsenite | multiple interactions | ISO | Pced1b (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of PCED1B mRNA | CTD | PMID:34876320 | sulforaphane | decreases expression | ISO | PCED1B (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of PCED1B mRNA | CTD | PMID:31838189 | terbufos | decreases methylation | ISO | PCED1B (Homo sapiens) | 6480464 | terbufos results in decreased methylation of PCED1B promoter | CTD | PMID:22847954 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of PCED1B mRNA | CTD | PMID:31150632 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of PCED1B mRNA | CTD | PMID:34492290 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of PCED1B gene | CTD | PMID:27618143 | urethane | decreases expression | ISO | PCED1B (Homo sapiens) | 6480464 | Urethane results in decreased expression of PCED1B mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Pced1b (Mus musculus) | 6480464 | Valproic Acid affects the expression of PCED1B mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | ISO | Pced1b (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of PCED1B mRNA | CTD | PMID:21427059 | vincristine | decreases expression | ISO | PCED1B (Homo sapiens) | 6480464 | Vincristine results in decreased expression of PCED1B mRNA | CTD | PMID:23649840 | zoledronic acid | increases expression | ISO | PCED1B (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of PCED1B mRNA | CTD | PMID:24714768 | |