Mageb2 (MAGE family member B2) - Rat Genome Database

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Gene: Mageb2 (MAGE family member B2) Rattus norvegicus
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Symbol: Mageb2
Name: MAGE family member B2
RGD ID: 1560904
Description: Predicted to be located in cytoplasm. Orthologous to human MAGEB2 (MAGE family member B2); INTERACTS WITH bisphenol A; 5-aza-2'-deoxycytidine (ortholog); 5-fluorouracil (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC102553413; LOC302744; Mageb1; melanoma antigen family B, 1; melanoma antigen family B, 2; melanoma-associated antigen B2; melanoma-associated antigen B2-like; melanoma-associated antigen B4; RGD1560904; similar to melanoma antigen family B, 2; uncharacterized LOC102553413
RGD Orthologs
Human
Mouse
Bonobo
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X54,778,318 - 54,784,040 (-)NCBIGRCr8
mRatBN7.2X50,827,538 - 50,833,272 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX50,827,563 - 50,833,151 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X54,807,024 - 54,811,144 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X55,008,041 - 55,009,983 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X73,077,761 - 73,079,281 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX51,363,308 - 51,368,908 (-)NCBICelera
Cytogenetic MapXq21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10706124  


Genomics

Comparative Map Data
Mageb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X54,778,318 - 54,784,040 (-)NCBIGRCr8
mRatBN7.2X50,827,538 - 50,833,272 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX50,827,563 - 50,833,151 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X54,807,024 - 54,811,144 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X55,008,041 - 55,009,983 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X73,077,761 - 73,079,281 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX51,363,308 - 51,368,908 (-)NCBICelera
Cytogenetic MapXq21NCBI
MAGEB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X30,215,563 - 30,220,089 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX30,215,563 - 30,220,089 (+)EnsemblGRCh38hg38GRCh38
GRCh37X30,233,680 - 30,238,206 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,143,601 - 30,148,127 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X29,993,336 - 29,997,861NCBI
CeleraX34,355,297 - 34,359,830 (+)NCBICelera
Cytogenetic MapXp21.2NCBI
HuRefX27,970,706 - 27,975,164 (+)NCBIHuRef
CHM1_1X30,264,618 - 30,269,149 (+)NCBICHM1_1
T2T-CHM13v2.0X29,807,905 - 29,812,440 (+)NCBIT2T-CHM13v2.0
Mageb4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X85,293,862 - 85,299,825 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX85,293,860 - 85,348,699 (-)EnsemblGRCm39 Ensembl
GRCm38X86,250,256 - 86,256,219 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX86,250,254 - 86,305,093 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X83,495,595 - 83,501,558 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X82,502,979 - 82,508,938 (-)NCBIMGSCv36mm8
CeleraX77,496,548 - 77,498,783 (-)NCBICelera
Cytogenetic MapXC1NCBI
cM MapX39.71NCBI
MAGEB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X31,999,839 - 32,005,524 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X32,003,219 - 32,008,904 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X22,804,983 - 22,810,236 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X30,366,930 - 30,371,454 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX30,369,947 - 30,370,906 (+)Ensemblpanpan1.1panPan2
LOC102159844
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X25,895,424 - 26,030,203 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X28,112,653 - 28,296,432 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAGEB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X28,619,651 - 28,624,412 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX28,622,915 - 28,623,862 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605630,605,109 - 30,609,010 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Mageb2
11 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000050661   ⟹   ENSRNOP00000090919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX50,827,563 - 50,833,151 (-)Ensembl
RefSeq Acc Id: XM_039100331   ⟹   XP_038956259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X54,778,318 - 54,784,040 (-)NCBI
mRatBN7.2X50,827,538 - 50,833,272 (-)NCBI
RefSeq Acc Id: XM_063280373   ⟹   XP_063136443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X54,778,318 - 54,784,040 (-)NCBI
RefSeq Acc Id: XM_063280374   ⟹   XP_063136444
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X54,778,318 - 54,783,404 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038956259 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136443 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136444 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96045 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000090919
  ENSRNOP00000090919.1
RefSeq Acc Id: XP_038956259   ⟸   XM_039100331
- UniProtKB: A0A8I6AAL9 (UniProtKB/TrEMBL),   A6IPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000090919   ⟸   ENSRNOT00000050661
RefSeq Acc Id: XP_063136443   ⟸   XM_063280373
RefSeq Acc Id: XP_063136444   ⟸   XM_063280374
Protein Domains
MAGE

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560904 AgrOrtholog
Ensembl Genes ENSRNOG00000028179 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050661.6 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
  MHD_dom UniProtKB/TrEMBL
NCBI Gene Mageb2 ENTREZGENE
PANTHER MELANOMA-ASSOCIATED ANTIGEN B4 UniProtKB/TrEMBL
  PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
PhenoGen Mageb2 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028179 RatGTEx
SMART MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
UniProt A0A8I6AAL9 ENTREZGENE, UniProtKB/TrEMBL
  A6IPW8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Mageb2  MAGE family member B2  LOC102553413  uncharacterized LOC102553413  Data merged from RGD:7610508 737654 PROVISIONAL
2015-12-16 Mageb2  MAGE family member B2  Mageb2  melanoma antigen family B, 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102553413  uncharacterized LOC102553413      Symbol and Name status set to provisional 70820 PROVISIONAL
2011-02-18 Mageb2  melanoma antigen family B, 2  Mageb1  melanoma antigen family B, 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Mageb1  melanoma antigen family B, 1  RGD1560904  similar to melanoma antigen family B, 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1560904  similar to melanoma antigen family B, 2   RGD1560904_predicted  similar to melanoma antigen family B, 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560904_predicted  similar to melanoma antigen family B, 2 (predicted)  LOC302744  similar to melanoma antigen family B, 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302744  similar to melanoma antigen family B, 2      Symbol and Name status set to provisional 70820 PROVISIONAL