Gene: Phox2b (paired-like homeobox 2b) Rattus norvegicus
Symbol: Phox2b
Name: paired-like homeobox 2b
Description: ENCODES a protein that exhibits RNA polymerase II core promoter proximal region sequence-specific DNA binding (ortholog); RNA polymerase II regulatory region sequence-specific DNA binding (ortholog); transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding (ortholog); INVOLVED IN autonomic nervous system development (ortholog); brainstem development (ortholog); cell development (ortholog); ASSOCIATED WITH Congenital Central Hypoventilation Syndrome (ortholog); Hirschsprung disease ganglioneuroblastoma (ortholog); Hypoventilation (ortholog); FOUND IN nuclear chromatin (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; copper atom; copper(0)
Type: protein-coding
RefSeq Status: MODEL
Also known as: NBPhox; neuroblastoma Phox; paired mesoderm homeobox protein 2B
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01442,711,438 - 42,718,707 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01442,510,540 - 42,514,526 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41443,675,180 - 43,677,970 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1440,219,013 - 40,226,258 (+)NCBI
Cytogenetic Map14p11NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Phox2b
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1560582
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2016-05-10
Status: ACTIVE