Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of SETD6 mRNA | CTD | PMID:23649840 | (1->4)-beta-D-glucan | multiple interactions | ISO | Setd6 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SETD6 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | ISO | Setd6 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SETD6 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Estradiol results in increased expression of SETD6 mRNA | CTD | PMID:32030086 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Setd6 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SETD6 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SETD6 mRNA | CTD | PMID:33387578 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | SETD6 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of SETD6 gene | CTD | PMID:31601247 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SETD6 mRNA | CTD | PMID:30047161 | acrolein | multiple interactions | ISO | SETD6 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of SETD6 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of SETD6 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | ISO | Setd6 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of SETD6 mRNA | CTD | PMID:19770486 | alpha-pinene | multiple interactions | ISO | SETD6 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of SETD6 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of SETD6 mRNA | CTD | PMID:32699268 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of SETD6 mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SETD6 mRNA | CTD | PMID:33212167 | atrazine | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of SETD6 mRNA | CTD | PMID:22378314 | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SETD6 mRNA | CTD | PMID:33854195 | benzo[a]pyrene | increases expression | ISO | Setd6 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SETD6 mRNA | CTD | PMID:19770486 and PMID:22228805 | berberine | increases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Berberine results in increased expression of SETD6 mRNA | CTD | PMID:27311644 | bis(2-chloroethyl) sulfide | increases expression | ISO | Setd6 (Mus musculus) | 6480464 | Mustard Gas results in increased expression of SETD6 mRNA | CTD | PMID:26392148 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SETD6 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | SETD6 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SETD6 mRNA | CTD | PMID:32030086 | bisphenol A | decreases expression | ISO | Setd6 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SETD6 mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SETD6 mRNA | CTD | PMID:30816183 and PMID:32528016 | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of SETD6 mRNA | CTD | PMID:19167457 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of SETD6 mRNA | CTD | PMID:33453195 | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SETD6 mRNA | CTD | PMID:33854195 | choline | multiple interactions | ISO | Setd6 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SETD6 gene | CTD | PMID:20938992 | chrysene | increases expression | ISO | Setd6 (Mus musculus) | 6480464 | chrysene results in increased expression of SETD6 mRNA | CTD | PMID:26377693 | copper(II) sulfate | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SETD6 mRNA | CTD | PMID:19549813 | crocidolite asbestos | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in decreased expression of SETD6 mRNA | CTD | PMID:29523930 | dibutyl phthalate | decreases expression | ISO | Setd6 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of SETD6 mRNA | CTD | PMID:21266533 | elemental selenium | multiple interactions | ISO | SETD6 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of SETD6 mRNA | CTD | PMID:19244175 | elemental selenium | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Selenium results in decreased expression of SETD6 mRNA | CTD | PMID:19244175 | ethyl methanesulfonate | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of SETD6 mRNA | CTD | PMID:23649840 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SETD6 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Setd6 (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SETD6 mRNA | CTD | PMID:33387578 | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SETD6 mRNA | CTD | PMID:33854195 | hypochlorous acid | decreases expression | ISO | Setd6 (Mus musculus) | 6480464 | Hypochlorous Acid results in decreased expression of SETD6 mRNA | CTD | PMID:19376150 | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SETD6 mRNA | CTD | PMID:33854195 | inulin | multiple interactions | ISO | Setd6 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SETD6 mRNA | CTD | PMID:36331819 | L-methionine | multiple interactions | ISO | Setd6 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SETD6 gene | CTD | PMID:20938992 | maneb | multiple interactions | ISO | Setd6 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of SETD6 mRNA | CTD | PMID:36117858 | menadione | affects expression | ISO | SETD6 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of SETD6 mRNA | CTD | PMID:20044591 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of SETD6 mRNA | CTD | PMID:30467583 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of SETD6 mRNA | CTD | PMID:30047161 | methotrexate | increases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of SETD6 mRNA | CTD | PMID:17400583 | methyl methanesulfonate | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of SETD6 mRNA | CTD | PMID:23649840 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of SETD6 mRNA | CTD | PMID:24136188 | ochratoxin A | decreases expression | EXP | | 6480464 | ochratoxin A results in decreased expression of SETD6 mRNA | CTD | PMID:22124623 | ozone | multiple interactions | ISO | SETD6 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of SETD6 mRNA more ... | CTD | PMID:32699268 | paraquat | multiple interactions | ISO | Setd6 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of SETD6 mRNA | CTD | PMID:36117858 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Setd6 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SETD6 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SETD6 mRNA | CTD | PMID:36331819 | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of SETD6 mRNA | CTD | PMID:30047161 | quercetin | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of SETD6 mRNA | CTD | PMID:21632981 | selenium atom | multiple interactions | ISO | SETD6 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of SETD6 mRNA | CTD | PMID:19244175 | selenium atom | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Selenium results in decreased expression of SETD6 mRNA | CTD | PMID:19244175 | silicon dioxide | increases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of SETD6 mRNA | CTD | PMID:25895662 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of SETD6 mRNA | CTD | PMID:19281266 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of SETD6 mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SETD6 mRNA | CTD | PMID:31533062 | tetrachloromethane | increases expression | ISO | Setd6 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of SETD6 mRNA | CTD | PMID:31919559 | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SETD6 mRNA | CTD | PMID:33854195 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of SETD6 mRNA | CTD | PMID:34492290 | trovafloxacin | decreases expression | ISO | Setd6 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of SETD6 mRNA | CTD | PMID:35537566 | valproic acid | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SETD6 mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | SETD6 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SETD6 mRNA | CTD | PMID:25979313 | vincristine | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of SETD6 mRNA | CTD | PMID:23649840 | vitamin E | decreases expression | ISO | SETD6 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of SETD6 mRNA | CTD | PMID:19244175 | vitamin E | multiple interactions | ISO | SETD6 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of SETD6 mRNA | CTD | PMID:19244175 | |