Pole3-ps2 (DNA polymerase epsilon 3, accessory subunit, pseudogene 2) - Rat Genome Database

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Gene: Pole3-ps2 (DNA polymerase epsilon 3, accessory subunit, pseudogene 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Pole3-ps2
Name: DNA polymerase epsilon 3, accessory subunit, pseudogene 2
RGD ID: 1560349
Description: Predicted to enable protein heterodimerization activity. Orthologous to human POLE3 (DNA polymerase epsilon 3, accessory subunit).
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: AABR07027368.1; LOC364694; RGD1560349; similar to histone-fold protein CHRAC17
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81726,341,522 - 26,341,968 (+)NCBIGRCr8
mRatBN7.21726,135,927 - 26,136,417 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1726,135,927 - 26,136,235 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1726,135,927 - 26,136,235 (+)NCBImRatBN7.2 Ensembl
Rnor_6.01726,772,292 - 26,772,738 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1726,772,096 - 26,772,732 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01728,688,332 - 28,688,778 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41732,204,699 - 32,205,145 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1725,777,642 - 25,778,088 (+)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
Additional References at PubMed
PMID:19182904  


Genomics

Variants

.
Variants in Pole3-ps2
3 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat


Expression


Sequence

Nucleotide Sequences
GenBank Nucleotide JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000071866   ⟹   ENSRNOP00000065674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1726,135,927 - 26,136,235 (+)Ensembl
Protein Sequences
Ensembl Protein ENSRNOP00000065674.2
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000065674   ⟸   ENSRNOT00000071866

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R882-F1-model_v2 AlphaFold M0R882 1-185 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560349 AgrOrtholog
BioCyc Gene G2FUF-9696 BioCyc
Ensembl Genes ENSRNOG00000047910 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000071866.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
InterPro Histone-fold UniProtKB/TrEMBL
NCBI Gene 364694 ENTREZGENE
PANTHER DNA POLYMERASE EPSILON SUBUNIT 3 UniProtKB/TrEMBL
  DNA POLYMERASE EPSILON SUBUNIT 3 UniProtKB/TrEMBL
PhenoGen Pole3-ps2 PhenoGen
RatGTEx ENSRNOG00000047910 RatGTEx
Superfamily-SCOP SSF47113 UniProtKB/TrEMBL
UniProt M0R882_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-10 Pole3-ps2  DNA polymerase epsilon 3, accessory subunit, pseudogene 2  RGD1560349  similar to histone-fold protein CHRAC17  Symbol and Name Changed 1299863 APPROVED
2022-06-02 RGD1560349  similar to histone-fold protein CHRAC17  AABR07027368.1    Data merged from RGD:15005385 737654 PROVISIONAL
2019-11-08 AABR07027368.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 RGD1560349  similar to histone-fold protein CHRAC17   RGD1560349_predicted  similar to histone-fold protein CHRAC17 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560349_predicted  similar to histone-fold protein CHRAC17 (predicted)  LOC364694  similar to histone-fold protein CHRAC17  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC364694  similar to histone-fold protein CHRAC17      Symbol and Name status set to provisional 70820 PROVISIONAL