Pabir2 (PABIR family member 2) - Rat Genome Database

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Gene: Pabir2 (PABIR family member 2) Rattus norvegicus
Analyze
Symbol: Pabir2
Name: PABIR family member 2
RGD ID: 1560129
Description: Predicted to enable protein serine/threonine phosphatase inhibitor activity. Orthologous to human PABIR2 (PABIR family member 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fam122b; family with sequence similarity 122B; LOC100909732; LOC501647; protein FAM122B-like; RGD1560129; similar to RIKEN cDNA 4632404H22
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X137,908,653 - 137,935,153 (-)NCBIGRCr8
mRatBN7.2X132,989,124 - 133,015,625 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX132,989,124 - 133,015,580 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX135,149,167 - 135,175,114 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X138,732,031 - 138,757,978 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X136,297,700 - 136,323,647 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,853,453 - 157,879,939 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX157,854,272 - 157,879,928 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 EnsemblX158,350,347 - 158,376,783 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X152,478,768 - 152,505,246 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X140,193,647 - 140,219,594NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic MapXq36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Pabir2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X137,908,653 - 137,935,153 (-)NCBIGRCr8
mRatBN7.2X132,989,124 - 133,015,625 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX132,989,124 - 133,015,580 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX135,149,167 - 135,175,114 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X138,732,031 - 138,757,978 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X136,297,700 - 136,323,647 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,853,453 - 157,879,939 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX157,854,272 - 157,879,928 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 EnsemblX158,350,347 - 158,376,783 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X152,478,768 - 152,505,246 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X140,193,647 - 140,219,594NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic MapXq36NCBI
PABIR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X134,769,566 - 134,797,205 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX134,769,566 - 134,797,232 (-)EnsemblGRCh38hg38GRCh38
GRCh37X133,903,596 - 133,931,235 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X133,731,262 - 133,758,378 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX134,290,355 - 134,318,021 (-)NCBICelera
Cytogenetic MapXq26.3NCBI
HuRefX123,302,899 - 123,329,379 (-)NCBIHuRef
CHM1_1X133,815,204 - 133,842,706 (-)NCBICHM1_1
T2T-CHM13v2.0X133,094,679 - 133,122,269 (-)NCBIT2T-CHM13v2.0
Pabir2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X52,332,292 - 52,358,728 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX52,332,292 - 52,358,682 (-)EnsemblGRCm39 Ensembl
GRCm38X53,243,415 - 53,269,850 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX53,243,415 - 53,269,805 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X50,596,592 - 50,622,982 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X49,488,061 - 49,513,658 (-)NCBIMGSCv36mm8
CeleraX40,668,449 - 40,695,187 (-)NCBICelera
Cytogenetic MapXA5NCBI
cM MapX29.43NCBI
Pabir2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955473208,697 - 231,838 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955473207,755 - 231,781 (+)NCBIChiLan1.0ChiLan1.0
PABIR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X134,205,009 - 134,232,247 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X134,208,607 - 134,235,784 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X123,920,228 - 123,946,120 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X134,216,272 - 134,241,898 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX134,216,312 - 134,241,887 (-)Ensemblpanpan1.1panPan2
PABIR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X105,367,621 - 105,416,545 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX105,200,746 - 105,416,596 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX91,506,991 - 91,527,288 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X107,091,987 - 107,278,986 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX107,091,840 - 107,279,077 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X104,669,579 - 104,689,871 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X106,535,767 - 106,556,048 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X106,327,249 - 106,347,550 (-)NCBIUU_Cfam_GSD_1.0
Pabir2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X103,530,438 - 103,574,110 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936691383,986 - 410,875 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936691383,976 - 426,911 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PABIR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX110,593,937 - 110,617,787 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X110,570,091 - 110,617,779 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X126,460,757 - 126,481,778 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PABIR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X109,939,033 - 109,965,435 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX109,941,606 - 109,964,434 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606547,545,423 - 47,571,991 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pabir2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479714,475,347 - 14,496,427 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479714,473,450 - 14,496,732 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pabir2
1 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1768
Count of miRNA genes:370
Interacting mature miRNAs:537
Transcripts:ENSRNOT00000003145, ENSRNOT00000066874
Prediction methods:Microtar, Miranda, Pita, Pita,Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat

Markers in Region
px-42a6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X132,996,306 - 132,996,446 (-)MAPPERmRatBN7.2
Rnor_6.0X157,872,617 - 157,872,756NCBIRnor6.0
Rnor_6.0X158,369,449 - 158,369,588NCBIRnor6.0
Rnor_5.0X152,996,092 - 152,996,231UniSTSRnor5.0
Rnor_5.0X152,497,924 - 152,498,063UniSTSRnor5.0
RGSC_v3.4X140,200,830 - 140,200,969UniSTSRGSC3.4
Cytogenetic MapXq36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 12
Below cutoff 3 29 17 14 5 14 1 1 45 21 33 10 1

Sequence


RefSeq Acc Id: ENSRNOT00000003145   ⟹   ENSRNOP00000003145
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX157,854,325 - 157,877,230 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000066874   ⟹   ENSRNOP00000060417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX132,989,137 - 133,015,580 (-)Ensembl
Rnor_6.0 EnsemblX158,350,347 - 158,376,783 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080538   ⟹   ENSRNOP00000070925
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX158,351,156 - 158,374,062 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000089777   ⟹   ENSRNOP00000069628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX132,989,124 - 133,015,072 (-)Ensembl
Rnor_6.0 EnsemblX157,854,272 - 157,879,928 (+)Ensembl
RefSeq Acc Id: NM_001166586   ⟹   NP_001160058
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,908,653 - 137,934,600 (-)NCBI
mRatBN7.2X132,989,124 - 133,015,072 (-)NCBI
Rnor_6.0X157,853,993 - 157,879,939 (+)NCBI
Rnor_5.0X152,478,768 - 152,505,246 (+)NCBI
RGSC_v3.4X140,193,647 - 140,219,594 (-)RGD
Sequence:
RefSeq Acc Id: XM_006257643   ⟹   XP_006257705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,908,658 - 137,935,149 (-)NCBI
mRatBN7.2X132,990,915 - 133,015,623 (-)NCBI
Rnor_6.0X157,853,453 - 157,877,477 (+)NCBI
Rnor_5.0X152,478,768 - 152,505,246 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006257648   ⟹   XP_006257710
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,908,658 - 137,935,150 (-)NCBI
mRatBN7.2X132,989,124 - 133,015,622 (-)NCBI
Rnor_6.0X157,853,453 - 157,879,934 (+)NCBI
Rnor_5.0X152,478,768 - 152,505,246 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008773633   ⟹   XP_008771855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,908,658 - 137,935,147 (-)NCBI
mRatBN7.2X132,989,124 - 133,015,622 (-)NCBI
Rnor_6.0X157,853,453 - 157,879,934 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099984   ⟹   XP_038955912
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,908,658 - 137,935,153 (-)NCBI
mRatBN7.2X132,990,915 - 133,015,625 (-)NCBI
RefSeq Acc Id: XM_039099985   ⟹   XP_038955913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,908,658 - 137,935,152 (-)NCBI
mRatBN7.2X132,990,915 - 133,015,625 (-)NCBI
RefSeq Acc Id: XM_039099986   ⟹   XP_038955914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,908,658 - 137,935,151 (-)NCBI
mRatBN7.2X132,989,124 - 133,015,624 (-)NCBI
RefSeq Acc Id: XM_039099987   ⟹   XP_038955915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,908,658 - 137,935,151 (-)NCBI
mRatBN7.2X132,989,124 - 133,015,624 (-)NCBI
RefSeq Acc Id: XM_039099988   ⟹   XP_038955916
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,911,368 - 137,935,153 (-)NCBI
mRatBN7.2X132,991,839 - 133,015,625 (-)NCBI
RefSeq Acc Id: XM_039099989   ⟹   XP_038955917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X137,908,658 - 137,935,153 (-)NCBI
mRatBN7.2X132,990,919 - 133,015,625 (-)NCBI
RefSeq Acc Id: NP_001160058   ⟸   NM_001166586
- UniProtKB: A0A0G2JVV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257710   ⟸   XM_006257648
- Peptide Label: isoform X7
- UniProtKB: A0A0G2QBZ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257705   ⟸   XM_006257643
- Peptide Label: isoform X3
- UniProtKB: A6KUJ4 (UniProtKB/TrEMBL),   A0A0G2JVV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008771855   ⟸   XM_008773633
- Peptide Label: isoform X6
- UniProtKB: A0A0G2QBZ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038955915   ⟸   XM_039099987
- Peptide Label: isoform X5
- UniProtKB: A0A0G2QBZ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955914   ⟸   XM_039099986
- Peptide Label: isoform X4
- UniProtKB: A0A0G2QBZ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955913   ⟸   XM_039099985
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JVV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955912   ⟸   XM_039099984
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JVV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955917   ⟸   XM_039099989
- Peptide Label: isoform X8
- UniProtKB: A0A0G2QBZ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955916   ⟸   XM_039099988
- Peptide Label: isoform X8
- UniProtKB: A0A0G2QBZ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000060417   ⟸   ENSRNOT00000066874
RefSeq Acc Id: ENSRNOP00000069628   ⟸   ENSRNOT00000089777
RefSeq Acc Id: ENSRNOP00000070925   ⟸   ENSRNOT00000080538
RefSeq Acc Id: ENSRNOP00000003145   ⟸   ENSRNOT00000003145

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZN42-F1-model_v2 AlphaFold D3ZN42 1-254 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560129 AgrOrtholog
BioCyc Gene G2FUF-978 BioCyc
Ensembl Genes ENSRNOG00000002285 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000050146 Ensembl
Ensembl Transcript ENSRNOT00000066874.4 UniProtKB/TrEMBL
  ENSRNOT00000089777 ENTREZGENE
  ENSRNOT00000089777.2 UniProtKB/TrEMBL
InterPro FAM122 UniProtKB/TrEMBL
NCBI Gene 501647 ENTREZGENE
PANTHER PABIR FAMILY MEMBER 2 UniProtKB/TrEMBL
  PTHR22227 UniProtKB/TrEMBL
PhenoGen Pabir2 PhenoGen
RatGTEx ENSRNOG00000002285 RatGTEx
  ENSRNOG00000050146 RatGTEx
UniProt A0A0G2JVV0 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2QBZ6 ENTREZGENE, UniProtKB/TrEMBL
  A6KUJ4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Pabir2  PABIR family member 2  LOC100909732  protein FAM122B-like  Data merged from RGD:6501955 737654 PROVISIONAL
2020-10-27 Pabir2  PABIR family member 2  Fam122b  family with sequence similarity 122B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100909732  protein FAM122B-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-07 Fam122b  family with sequence similarity 122B  RGD1560129_predicted  similar to RIKEN cDNA 4632404H22 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1560129_predicted  similar to RIKEN cDNA 4632404H22 (predicted)  LOC501647  similar to RIKEN cDNA 4632404H22  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501647  similar to RIKEN cDNA 4632404H22      Symbol and Name status set to provisional 70820 PROVISIONAL