Rps17l2 (ribosomal protein S17 like 2) - Rat Genome Database

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Gene: Rps17l2 (ribosomal protein S17 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps17l2 (Ensembl: AABR07068536.1)
Name: ribosomal protein S17 like 2 (Ensembl:similar to 40S ribosomal protein S17)
RGD ID: 1559955
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 4. Orthologous to human RPS17 (ribosomal protein S17).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 40S ribosomal protein S17-like; LOC367324; RGD1559955; ribosomal protein S17 like 1; Rps17l1; similar to 40S ribosomal protein S17; small ribosomal subunit protein eS17-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89106,540,522 - 106,541,147 (+)NCBIGRCr8
mRatBN7.2999,093,272 - 99,093,890 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl999,093,460 - 99,093,867 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.09106,913,887 - 106,914,518 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.09106,497,335 - 106,497,953 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4997,909,269 - 97,909,676 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera996,531,421 - 96,532,052 (+)NCBICelera
Cytogenetic Map9q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
translation  (IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rps17l2
2 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:40
Interacting mature miRNAs:41
Transcripts:ENSRNOT00000046179
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)992491589100929786Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat


Expression


Sequence


RefSeq Acc Id: XM_039084762   ⟹   XP_038940690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89106,540,522 - 106,541,147 (+)NCBI
mRatBN7.2999,093,272 - 99,093,890 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038940690 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025888.7
  ENSRNOP00000041920
  ENSRNOP00000041920.3
RefSeq Acc Id: XP_038940690   ⟸   XM_039084762
- UniProtKB: D3ZKG6 (UniProtKB/TrEMBL),   A0A0H2UHQ8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZKG6-F1-model_v2 AlphaFold D3ZKG6 1-135 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559955 AgrOrtholog
BioCyc Gene G2FUF-26564 BioCyc
Ensembl Genes ENSRNOG00000019106 UniProtKB/TrEMBL
  ENSRNOG00000032765 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025888.8 UniProtKB/TrEMBL
  ENSRNOT00000046179.6 UniProtKB/TrEMBL
Gene3D-CATH 1.10.60.20 UniProtKB/TrEMBL
InterPro Ribosomal_S17e UniProtKB/TrEMBL
  Ribosomal_S17e_CS UniProtKB/TrEMBL
  RPS17e-like_sf UniProtKB/TrEMBL
NCBI Gene 367324 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S17 UniProtKB/TrEMBL
  40S RIBOSOMAL PROTEIN S17 UniProtKB/TrEMBL
  PTHR10732 UniProtKB/TrEMBL
Pfam Ribosomal_S17e UniProtKB/TrEMBL
PhenoGen Rps17l2 PhenoGen
PROSITE RIBOSOMAL_S17E UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019106 RatGTEx
  ENSRNOG00000032765 RatGTEx
Superfamily-SCOP SSF116820 UniProtKB/TrEMBL
UniProt A0A0H2UHQ8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZKG6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-13 Rps17l2  ribosomal protein S17 like 2  Rps17l1  ribosomal protein S17 like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Rps17l1  ribosomal protein S17 like 1  RGD1559955  similar to 40S ribosomal protein S17  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1559955  similar to 40S ribosomal protein S17   RGD1559955_predicted  similar to 40S ribosomal protein S17 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559955_predicted  similar to 40S ribosomal protein S17 (predicted)  LOC367324  similar to 40S ribosomal protein S17  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC367324  similar to 40S ribosomal protein S17      Symbol and Name status set to provisional 70820 PROVISIONAL