Magea14l1 (MAGE family member A14 like 1) - Rat Genome Database

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Gene: Magea14l1 (MAGE family member A14 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Magea14l1 (Ensembl: RGD1559726)
Name: MAGE family member A14 like 1 (Ensembl:similar to melanoma antigen family A, 6)
RGD ID: 1559726
Description: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including MAGEA10 (MAGE family member A10).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC307203; melanoma-associated antigen 10-like; RGD1559726; similar to melanoma antigen family A, 6
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81882,603,112 - 82,604,471 (+)NCBIGRCr8
mRatBN7.21880,328,367 - 80,329,547 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1880,328,567 - 80,329,469 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01884,161,794 - 84,163,424 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1884,162,467 - 84,163,369 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01883,222,457 - 83,223,422 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41883,698,590 - 83,699,492 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1878,909,929 - 78,911,559 (+)NCBICelera
Cytogenetic Map18q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Magea14l1
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:29
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000047841
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)184852004483828827Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185146473383218561Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)185917211583828827Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)185979647883828827Rat
6903356Bp354Blood pressure QTL 3544.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647883828827Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system reproductive system respiratory system
High
Medium
Low
Below cutoff 5 2 1

Sequence


RefSeq Acc Id: ENSRNOT00000047841   ⟹   ENSRNOP00000054987
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1880,328,567 - 80,329,469 (+)Ensembl
Rnor_6.0 Ensembl1884,162,467 - 84,163,369 (+)Ensembl
RefSeq Acc Id: XM_225656   ⟹   XP_225656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81882,603,112 - 82,604,471 (+)NCBI
mRatBN7.21880,328,367 - 80,329,547 (+)NCBI
Rnor_6.01884,161,794 - 84,163,424 (+)NCBI
Rnor_5.01883,222,457 - 83,223,422 (+)NCBI
RGSC_v3.41883,698,590 - 83,699,492 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs XP_225656 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000054987
  ENSRNOP00000054987.4
RefSeq Acc Id: XP_225656   ⟸   XM_225656
- UniProtKB: D3ZS82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000054987   ⟸   ENSRNOT00000047841
Protein Domains
MAGE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZS82-F1-model_v2 AlphaFold D3ZS82 1-291 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559726 AgrOrtholog
BioCyc Gene G2FUF-6720 BioCyc
Ensembl Genes ENSRNOG00000034073 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047841.5 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
  MHD_dom UniProtKB/TrEMBL
KEGG Report rno:307203 UniProtKB/TrEMBL
NCBI Gene 307203 ENTREZGENE
PANTHER 1700080O16RIK PROTEIN UniProtKB/TrEMBL
  PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
PhenoGen Magea14l1 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000034073 RatGTEx
SMART MAGE UniProtKB/TrEMBL
UniProt D3ZS82 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Magea14l1  MAGE family member A14 like 1  RGD1559726  similar to melanoma antigen family A, 6  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1559726  similar to melanoma antigen family A, 6   RGD1559726_predicted  similar to melanoma antigen family A, 6 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559726_predicted  similar to melanoma antigen family A, 6 (predicted)  LOC307203  similar to melanoma antigen family A, 6  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC307203  similar to melanoma antigen family A, 6      Symbol and Name status set to provisional 70820 PROVISIONAL