Krtap13-2 (keratin associated protein 13-2) - Rat Genome Database

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Gene: Krtap13-2 (keratin associated protein 13-2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Krtap13-2
Name: keratin associated protein 13-2
RGD ID: 1559597
Description: Predicted to be located in cytosol and keratin filament. Orthologous to several human genes including KRTAP13-3 (keratin associated protein 13-3); INTERACTS WITH bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC501765; LOC501765; RGD1559597; similar to RIKEN cDNA 2310057N15
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81141,575,897 - 41,577,041 (+)NCBIGRCr8
mRatBN7.21128,089,681 - 28,090,825 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,089,681 - 28,090,825 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1136,775,790 - 36,776,933 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01129,476,016 - 29,477,159 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01128,655,323 - 28,656,469 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01128,739,165 - 28,740,309 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1128,739,219 - 28,739,743 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01132,359,246 - 32,360,390 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41128,612,582 - 28,613,726 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1127,805,239 - 27,806,383 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Krtap13-2
37 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:44
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000061620
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat

Markers in Region
RH139633  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21128,090,478 - 28,090,694 (+)MAPPERmRatBN7.2
Rnor_6.01128,739,963 - 28,740,178NCBIRnor6.0
Rnor_5.01132,360,044 - 32,360,259UniSTSRnor5.0
RGSC_v3.41128,613,380 - 28,613,595UniSTSRGSC3.4
Celera1127,806,037 - 27,806,252UniSTS
RH 3.4 Map11159.6UniSTS
Cytogenetic Map11q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system exocrine system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system appendage
High
Medium
Low 2 1
Below cutoff 1 1 1 1 1 1 2 7 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000061620   ⟹   ENSRNOP00000058337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1128,739,219 - 28,739,743 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116069   ⟹   ENSRNOP00000088503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1128,089,681 - 28,090,825 (+)Ensembl
RefSeq Acc Id: NM_001109325   ⟹   NP_001102795
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81141,575,897 - 41,577,041 (+)NCBI
mRatBN7.21128,089,681 - 28,090,825 (+)NCBI
Rnor_6.01128,739,165 - 28,740,309 (+)NCBI
Rnor_5.01132,359,246 - 32,360,390 (+)NCBI
RGSC_v3.41128,612,582 - 28,613,726 (+)RGD
Celera1127,805,239 - 27,806,383 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102795 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM10663 (Get FASTA)   NCBI Sequence Viewer  
  EDM10665 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000088503
  ENSRNOP00000088503.1
Reference Protein Sequences
RefSeq Acc Id: NP_001102795   ⟸   NM_001109325
- UniProtKB: A0A8I6A9J8 (UniProtKB/TrEMBL),   A6JLA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000058337   ⟸   ENSRNOT00000061620
RefSeq Acc Id: ENSRNOP00000088503   ⟸   ENSRNOT00000116069

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZK59-F1-model_v2 AlphaFold D3ZK59 1-174 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698032
Promoter ID:EPDNEW_R8556
Type:single initiation site
Name:Krtap13-2_1
Description:keratin associated protein 13-2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01128,739,164 - 28,739,224EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559597 AgrOrtholog
BioCyc Gene G2FUF-22014 BioCyc
Ensembl Genes ENSRNOG00000043083 Ensembl
  ENSRNOG00000063259 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000116069 ENTREZGENE
  ENSRNOT00000116069.1 UniProtKB/TrEMBL
InterPro PMG UniProtKB/TrEMBL
KEGG Report rno:501765 UniProtKB/TrEMBL
NCBI Gene 501765 ENTREZGENE
Pfam PMG UniProtKB/TrEMBL
PhenoGen Krtap13-2 PhenoGen
RatGTEx ENSRNOG00000043083 RatGTEx
  ENSRNOG00000063259 RatGTEx
UniProt A0A8I6A9J8 ENTREZGENE, UniProtKB/TrEMBL
  A6JLA0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Krtap13-2  keratin associated protein 13-2  RGD1559597  similar to RIKEN cDNA 2310057N15  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1559597  similar to RIKEN cDNA 2310057N15   RGD1559597_predicted  similar to RIKEN cDNA 2310057N15 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559597_predicted  similar to RIKEN cDNA 2310057N15 (predicted)  LOC501765  similar to RIKEN cDNA 2310057N15  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501765  similar to RIKEN cDNA 2310057N15      Symbol and Name status set to provisional 70820 PROVISIONAL