Unc5c (unc-5 netrin receptor C) - Rat Genome Database

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Gene: Unc5c (unc-5 netrin receptor C) Mus musculus
Analyze
Symbol: Unc5c
Name: unc-5 netrin receptor C
RGD ID: 1551856
MGI Page MGI
Description: Enables netrin receptor activity involved in chemorepulsion and tubulin binding activity. Involved in chemorepulsion of axon and netrin-activated signaling pathway. Acts upstream of or within several processes, including nervous system development; positive regulation of apoptotic process; and regulation of neuron migration. Located in several cellular components, including filopodium; growth cone; and lamellipodium. Is expressed in several structures, including brain; embryo mesenchyme; gonad; sensory organ; and skeleton. Orthologous to human UNC5C (unc-5 netrin receptor C).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6030473H24; AI047720; B130051O18Rik; netrin receptor UNC5C; rcm; rostral cerebellar malformation; UNC-5 homolog 3; unc-5 homolog C; unc5 homolog 3; Unc5h; Unc5h3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393141,171,360 - 141,540,685 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3141,170,977 - 141,540,685 (+)EnsemblGRCm39 Ensembl
GRCm383141,465,564 - 141,834,924 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3141,465,216 - 141,834,924 (+)EnsemblGRCm38mm10GRCm38
MGSCv373141,128,528 - 141,497,886 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363141,402,951 - 141,772,309 (+)NCBIMGSCv36mm8
Celera3147,889,997 - 148,247,699 (+)NCBICelera
Cytogenetic Map3H1NCBI
cM Map365.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axon guidance  (IAGP)
abnormal cerebellar granule layer morphology  (IAGP)
abnormal cerebellar layer morphology  (IAGP)
abnormal cerebellar lobule formation  (IAGP)
abnormal cerebellar molecular layer  (IAGP)
abnormal cerebellar Purkinje cell layer  (IAGP)
abnormal cerebellum anterior lobe morphology  (IEA)
abnormal cerebellum development  (IAGP)
abnormal cerebellum external granule cell layer morphology  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal cerebellum vermis lobule morphology  (IAGP)
abnormal corpora quadrigemina morphology  (IAGP)
abnormal corticospinal tract morphology  (IAGP)
abnormal epididymal fat pad morphology  (IAGP)
abnormal fat pad morphology  (IAGP)
abnormal gait  (IAGP)
abnormal inferior colliculus morphology  (IAGP)
abnormal innervation pattern to muscle  (IAGP)
abnormal neuronal migration  (IAGP)
abnormal phrenic nerve innervation pattern to diaphragm  (IAGP)
abnormal phrenic nerve morphology  (IAGP)
abnormal posture  (IAGP)
abnormal Purkinje cell morphology  (IAGP)
abnormal pyramidal decussation morphology  (IAGP)
abnormal spinal cord dorsal column morphology  (IAGP)
abnormal trochlear nerve morphology  (IAGP)
ataxia  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased locomotor activity  (IEA)
ectopic cerebellar granule cells  (IAGP)
ectopic Purkinje cell  (IAGP)
head bobbing  (IAGP)
hyperactivity  (IAGP)
increased fluid intake  (IAGP)
increased food intake  (IAGP)
increased inferior colliculus size  (IAGP)
increased locomotor activity  (IAGP)
male infertility  (IAGP)
postnatal growth retardation  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
reduced cerebellar foliation  (IAGP)
small cerebellum  (IAGP)
tremors  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1401878   PMID:1712903   PMID:9126743   PMID:9192846   PMID:9389662   PMID:9550145   PMID:10341242   PMID:10349636   PMID:10409504   PMID:10704383   PMID:10818148   PMID:10908620  
PMID:10964959   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11533026   PMID:11544199   PMID:12223565   PMID:12351186   PMID:12451134   PMID:12477932   PMID:12736344   PMID:14534138  
PMID:14562603   PMID:14750959   PMID:15186747   PMID:15226823   PMID:15788454   PMID:16141072   PMID:16141073   PMID:16364898   PMID:16510500   PMID:16537572   PMID:16602821   PMID:16723533  
PMID:17450135   PMID:17543537   PMID:17573818   PMID:17616930   PMID:17967459   PMID:18077458   PMID:18184911   PMID:18287559   PMID:18479186   PMID:18480165   PMID:18697905   PMID:18771734  
PMID:18842897   PMID:19539053   PMID:19592574   PMID:20493932   PMID:20628609   PMID:21150899   PMID:21267068   PMID:21307253   PMID:21677750   PMID:21862448   PMID:21873635   PMID:22154806  
PMID:22685302   PMID:22726835   PMID:23144223   PMID:23307742   PMID:23312517   PMID:23457482   PMID:23738838   PMID:24154525   PMID:24360543   PMID:24449837   PMID:24739528   PMID:24803655  
PMID:24952961   PMID:25419706   PMID:26147436   PMID:26264903   PMID:26503042   PMID:26633812   PMID:26633881   PMID:26687222   PMID:26858598   PMID:27568519   PMID:27784329   PMID:27819291  
PMID:28434801   PMID:28483977   PMID:30470704   PMID:30550785   PMID:30902550   PMID:30905607   PMID:31351040   PMID:32562661   PMID:33863723   PMID:33951080   PMID:34170322   PMID:34321664  
PMID:35247845   PMID:35831953   PMID:35927240   PMID:36028553   PMID:37321213   PMID:37557174   PMID:37818607   PMID:37823339   PMID:38187761  


Genomics

Comparative Map Data
Unc5c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393141,171,360 - 141,540,685 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3141,170,977 - 141,540,685 (+)EnsemblGRCm39 Ensembl
GRCm383141,465,564 - 141,834,924 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3141,465,216 - 141,834,924 (+)EnsemblGRCm38mm10GRCm38
MGSCv373141,128,528 - 141,497,886 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363141,402,951 - 141,772,309 (+)NCBIMGSCv36mm8
Celera3147,889,997 - 148,247,699 (+)NCBICelera
Cytogenetic Map3H1NCBI
cM Map365.57NCBI
UNC5C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38495,162,504 - 95,548,973 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl495,162,504 - 95,549,206 (-)EnsemblGRCh38hg38GRCh38
GRCh37496,083,655 - 96,470,124 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36496,308,712 - 96,689,185 (-)NCBINCBI36Build 36hg18NCBI36
Build 34496,446,866 - 96,827,340NCBI
Celera493,380,311 - 93,766,978 (-)NCBICelera
Cytogenetic Map4q22.3NCBI
HuRef491,820,282 - 92,206,879 (-)NCBIHuRef
CHM1_1496,060,693 - 96,447,078 (-)NCBICHM1_1
T2T-CHM13v2.0498,477,165 - 98,864,110 (-)NCBIT2T-CHM13v2.0
Unc5c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82232,854,352 - 233,208,482 (+)NCBIGRCr8
mRatBN7.22230,180,353 - 230,535,219 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2230,180,951 - 230,535,217 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2237,924,292 - 238,290,667 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02235,817,330 - 236,183,687 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02230,681,978 - 231,048,343 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02247,045,813 - 247,397,483 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2247,248,407 - 247,397,483 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02265,573,406 - 265,926,229 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42239,365,109 - 239,721,231 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12239,351,848 - 239,707,971 (+)NCBI
Celera2222,239,483 - 222,591,078 (+)NCBICelera
Cytogenetic Map2q44NCBI
Unc5c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554055,797,590 - 5,950,544 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554055,791,286 - 6,049,952 (-)NCBIChiLan1.0ChiLan1.0
UNC5C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2393,198,579 - 93,586,730 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1493,477,466 - 93,865,726 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0487,527,262 - 87,921,351 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1498,198,831 - 98,589,857 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl498,205,554 - 98,587,888 (-)Ensemblpanpan1.1panPan2
UNC5C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13217,981,286 - 18,333,111 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3217,987,464 - 18,333,602 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3223,609,404 - 23,959,891 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03218,164,222 - 18,513,849 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3218,167,485 - 18,513,818 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13218,134,124 - 18,485,245 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03217,955,873 - 18,306,960 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03221,584,814 - 21,936,742 (+)NCBIUU_Cfam_GSD_1.0
Unc5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530123,396,564 - 23,746,350 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366872,607,112 - 2,756,094 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366872,600,635 - 2,951,407 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC5C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8124,142,030 - 124,530,603 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18124,149,364 - 124,533,755 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
UNC5C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1743,405,666 - 43,786,436 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603721,777,546 - 22,164,042 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc5c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475723,151,485 - 23,537,706 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475723,145,200 - 23,537,812 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Unc5c
13605 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2550
Count of miRNA genes:805
Interacting mature miRNAs:1092
Transcripts:ENSMUST00000075282, ENSMUST00000106236, ENSMUST00000123631, ENSMUST00000130636, ENSMUST00000142762, ENSMUST00000151007, ENSMUST00000155416
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396607316147805636Mouse
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100372912147045722Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101307316149805637Mouse
1302093Orgwq5_morgan weight QTL 5 (mouse)Not determined3107376936147304689Mouse
1300619Cdcs1_mcytokine deficiency colitis susceptibility 1 (mouse)Not determined3109834882143835005Mouse
1301381Bomb1_mbone marrow pre-B 1 (mouse)Not determined3111133243145133417Mouse
1301100Bdt2_mbone density traits 2 (mouse)Not determined3114736617148736784Mouse
10043919Afpq8_mabdominal fat percent QTL 8 (mouse)Not determined3119057332153057456Mouse
1558868Ses9_msalmonella enteritidis susceptibility 9 (mouse)Not determined3119057332153057456Mouse
4141935Tgq15_mtriglyceride QTL 15 (mouse)Not determined119318586153318586Mouse
4142449Tgq14_mtriglyceride QTL 14 (mouse)Not determined119318586153318586Mouse
1302151Lprm2_mlymphoproliferation modifier 2 (mouse)Not determined3119778857153779044Mouse
10412240Alpq6_malcohol preference QTL 6 (mouse)Not determined3120772078154772078Mouse
4142245Pstc1_mperiosteal circumference 1 (mouse)Not determined3126270248159745316Mouse
1301218Letohc1_mlow ethanol consumption 1 (mouse)Not determined3126352986159745316Mouse
1301347Fpli_mfasting plasma insulin (mouse)Not determined3126460514159745316Mouse
1301563Alcp3_malcohol preference locus 3 (mouse)Not determined3130736935159745316Mouse
11039523Tbbr1_mTrypanosoma brucei brucei response 1 (mouse)3130849375159745316Mouse
1300753Eae10_msusceptibility to experimental allergic encephalomyelitis 10 (mouse)Not determined3131736617148451178Mouse
10412120Ccs3_mcolon cancer susceptibility 3 (mouse)Not determined3131754536146017669Mouse
1301528Loco1_mlocomotor activity 1 (mouse)Not determined3133461893159745316Mouse

Markers in Region
RH135837  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383141,832,627 - 141,832,737UniSTSGRCm38
MGSCv373141,495,591 - 141,495,701UniSTSGRCm37
Celera3148,245,402 - 148,245,512UniSTS
Cytogenetic Map3H1UniSTS
cM Map368.5UniSTS
D3Mit196  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383141,536,841 - 141,536,984UniSTSGRCm38
MGSCv373141,199,805 - 141,199,948UniSTSGRCm37
Celera3147,961,253 - 147,961,396UniSTS
Cytogenetic Map3H1UniSTS
cM Map369.2UniSTS
Whitehead Genetic348.1UniSTS
Whitehead/MRC_RH31561.98UniSTS
Whitehead_YAC3 UniSTS
D3Mit368  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383141,474,487 - 141,474,636UniSTSGRCm38
MGSCv373141,137,451 - 141,137,600UniSTSGRCm37
Celera3147,898,930 - 147,899,079UniSTS
Cytogenetic Map3H1UniSTS
cM Map370.0UniSTS
Whitehead_YAC3 UniSTS
Unc5c  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv373141,497,044 - 141,497,489UniSTSGRCm37
Celera3148,246,855 - 148,247,302UniSTS
Cytogenetic Map3H1UniSTS
cM Map368.5UniSTS
cM Map368.5UniSTS
Unc5c  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3H1UniSTS
cM Map368.5UniSTS
Unc5c  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383141,834,080 - 141,834,525UniSTSGRCm38
MGSCv373141,497,044 - 141,497,489UniSTSGRCm37
Celera3148,246,855 - 148,247,302UniSTS
Cytogenetic Map3H1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001293561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC102315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC157492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC158552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC170085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U72634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000075282   ⟹   ENSMUSP00000074758
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3141,171,335 - 141,535,230 (+)Ensembl
GRCm38.p6 Ensembl3141,465,574 - 141,829,469 (+)Ensembl
RefSeq Acc Id: ENSMUST00000106236   ⟹   ENSMUSP00000101843
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3141,170,977 - 141,540,685 (+)Ensembl
GRCm38.p6 Ensembl3141,465,216 - 141,834,924 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123631
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3141,495,613 - 141,497,747 (+)Ensembl
GRCm38.p6 Ensembl3141,789,852 - 141,791,986 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130636   ⟹   ENSMUSP00000117487
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3141,171,360 - 141,535,182 (+)Ensembl
GRCm38.p6 Ensembl3141,465,599 - 141,829,421 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142762   ⟹   ENSMUSP00000118212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3141,171,432 - 141,536,299 (+)Ensembl
GRCm38.p6 Ensembl3141,465,671 - 141,830,538 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151007
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3141,171,360 - 141,366,183 (+)Ensembl
GRCm38.p6 Ensembl3141,465,599 - 141,660,422 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155416
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3141,171,360 - 141,388,085 (+)Ensembl
GRCm38.p6 Ensembl3141,465,599 - 141,682,324 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200114
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3141,171,360 - 141,176,689 (+)Ensembl
GRCm38.p6 Ensembl3141,465,599 - 141,470,928 (+)Ensembl
RefSeq Acc Id: NM_001293561   ⟹   NP_001280490
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393141,171,360 - 141,540,685 (+)NCBI
GRCm383141,465,564 - 141,834,924 (+)NCBI
Celera3147,889,997 - 148,247,701 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009472   ⟹   NP_033498
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393141,171,360 - 141,540,685 (+)NCBI
GRCm383141,465,564 - 141,834,924 (+)NCBI
MGSCv373141,128,528 - 141,497,886 (+)RGD
Celera3147,889,997 - 148,247,701 (+)NCBI
cM Map3 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_033498   ⟸   NM_009472
- Peptide Label: isoform 2 precursor
- UniProtKB: Q8CD16 (UniProtKB/Swiss-Prot),   O08747 (UniProtKB/Swiss-Prot),   Q3URW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001280490   ⟸   NM_001293561
- Peptide Label: isoform 1 precursor
- UniProtKB: Q3UQ08 (UniProtKB/TrEMBL),   Q3URW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000117487   ⟸   ENSMUST00000130636
RefSeq Acc Id: ENSMUSP00000101843   ⟸   ENSMUST00000106236
RefSeq Acc Id: ENSMUSP00000074758   ⟸   ENSMUST00000075282
RefSeq Acc Id: ENSMUSP00000118212   ⟸   ENSMUST00000142762
Protein Domains
Death   Ig-like   Ig-like C2-type   TSP type-1   ZU5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08747-F1-model_v2 AlphaFold O08747 1-931 view protein structure

Promoters
RGD ID:6834631
Promoter ID:MM_KWN:36266
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day3,   Brain,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000106236,   OTTMUST00000062295,   OTTMUST00000062298,   OTTMUST00000062301,   UC008ROC.1,   UC008ROD.1,   UC008ROF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363141,127,861 - 141,129,212 (+)MPROMDB
RGD ID:6834600
Promoter ID:MM_KWN:36271
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000062302
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363141,452,421 - 141,452,921 (+)MPROMDB
RGD ID:6882508
Promoter ID:EPDNEW_M4705
Type:multiple initiation site
Name:Unc5c_1
Description:Mus musculus unc-5 netrin receptor C , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383141,465,599 - 141,465,659EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1095412 AgrOrtholog
Ensembl Genes ENSMUSG00000059921 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000075282 ENTREZGENE
  ENSMUST00000075282.10 UniProtKB/Swiss-Prot
  ENSMUST00000106236 ENTREZGENE
  ENSMUST00000106236.9 UniProtKB/Swiss-Prot
  ENSMUST00000130636.8 UniProtKB/TrEMBL
  ENSMUST00000142762.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.533.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.20.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.220.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DEATH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Death_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Death_UNC5C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNC5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UPA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZU5_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22253 UniProtKB/Swiss-Prot
MGD MGI:1095412 ENTREZGENE
NCBI Gene 22253 ENTREZGENE
PANTHER NETRIN RECEPTOR UNC5C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12582 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Death UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UPA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZU5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Unc5c PhenoGen
PRINTS TSP1REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZU5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DEATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TSP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZU5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82895 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9PVI4_MOUSE UniProtKB/TrEMBL
  O08747 ENTREZGENE
  Q3TPN7_MOUSE UniProtKB/TrEMBL
  Q3TSU2_MOUSE UniProtKB/TrEMBL
  Q3UQ08 ENTREZGENE, UniProtKB/TrEMBL
  Q3URW2 ENTREZGENE, UniProtKB/TrEMBL
  Q3UTY3_MOUSE UniProtKB/TrEMBL
  Q8CD16 ENTREZGENE
  UNC5C_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8CD16 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 Unc5c  unc-5 netrin receptor C    unc-5 homolog C (C. elegans)  Symbol and/or name change 5135510 APPROVED