Lrrc7 (leucine rich repeat containing 7) - Rat Genome Database

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Gene: Lrrc7 (leucine rich repeat containing 7) Mus musculus
Analyze
Symbol: Lrrc7
Name: leucine rich repeat containing 7
RGD ID: 1550331
MGI Page MGI
Description: Predicted to enable protein kinase binding activity. Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; protein localization to postsynapse; and receptor clustering. Predicted to be located in dendritic spine and filopodium. Predicted to be active in several cellular components, including axon initial segment; basolateral plasma membrane; and postsynaptic density membrane. Predicted to colocalize with actin cytoskeleton and postsynaptic membrane. Is expressed in brain; cortical plate; esophagus mesenchyme; spinal cord; and trachea mesenchyme. Used to study developmental disorder of mental health. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human LRRC7 (leucine rich repeat containing 7).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AK122498; B230334C09Rik; de; densin; densin 180; densin-180; leucine-rich repeat-containing protein 7; mKIAA1365; RIKEN cDNA B230334C09 gene
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393157,772,823 - 158,268,254 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3157,788,528 - 158,267,858 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl3157,772,823 - 157,781,749 (-)EnsemblGRCm39 Ensembl
GRCm383158,067,186 - 158,561,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3158,082,891 - 158,562,221 (-)EnsemblGRCm38mm10GRCm38
MGSCv373157,747,403 - 158,225,185 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363158,018,188 - 158,497,514 (-)NCBIMGSCv36mm8
Celera3164,551,795 - 165,021,656 (-)NCBICelera
Cytogenetic Map3H4NCBI
cM Map381.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. CaMKII regulation in information processing and storage. Coultrap SJ and Bayer KU, Trends Neurosci. 2012 Oct;35(10):607-18. doi: 10.1016/j.tins.2012.05.003. Epub 2012 Jun 19.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Substance dependence low-density whole genome association study in two distinct American populations. Yu Y, etal., Hum Genet. 2008 Jun;123(5):495-506. doi: 10.1007/s00439-008-0501-0. Epub 2008 Apr 26.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:16452087   PMID:17039495  
PMID:17114649   PMID:18407958   PMID:19208628   PMID:20124353   PMID:20392935   PMID:21267068   PMID:21610080   PMID:21873635   PMID:22072671   PMID:22794259   PMID:27507650   PMID:28363979  
PMID:28671696   PMID:28706196   PMID:29254152   PMID:29428562   PMID:29518331   PMID:31582721   PMID:32325033   PMID:32581705   PMID:34321999   PMID:36417873   PMID:36604605  


Genomics

Comparative Map Data
Lrrc7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393157,772,823 - 158,268,254 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3157,788,528 - 158,267,858 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl3157,772,823 - 157,781,749 (-)EnsemblGRCm39 Ensembl
GRCm383158,067,186 - 158,561,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3158,082,891 - 158,562,221 (-)EnsemblGRCm38mm10GRCm38
MGSCv373157,747,403 - 158,225,185 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363158,018,188 - 158,497,514 (-)NCBIMGSCv36mm8
Celera3164,551,795 - 165,021,656 (-)NCBICelera
Cytogenetic Map3H4NCBI
cM Map381.68NCBI
LRRC7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38169,567,922 - 70,144,364 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl169,567,922 - 70,151,945 (+)EnsemblGRCh38hg38GRCh38
GRCh37170,033,605 - 70,610,047 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36169,998,446 - 70,361,759 (+)NCBINCBI36Build 36hg18NCBI36
Build 34169,937,878 - 70,299,947NCBI
Celera168,515,739 - 68,879,117 (+)NCBICelera
Cytogenetic Map1p31.1NCBI
HuRef168,336,211 - 68,700,364 (+)NCBIHuRef
CHM1_1170,341,207 - 70,704,575 (+)NCBICHM1_1
T2T-CHM13v2.0169,444,558 - 70,022,853 (+)NCBIT2T-CHM13v2.0
Lrrc7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82249,792,441 - 250,294,267 (-)NCBIGRCr8
mRatBN7.22247,146,616 - 247,634,945 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2247,147,752 - 247,634,547 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2254,879,113 - 255,357,086 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02252,772,486 - 253,250,577 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02247,741,203 - 248,227,243 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02264,910,594 - 265,300,860 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2264,910,594 - 265,300,868 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02283,549,882 - 283,934,360 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42256,228,792 - 256,644,029 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12256,243,398 - 256,458,663 (-)NCBI
Celera2238,947,973 - 239,318,491 (-)NCBICelera
Cytogenetic Map2q45NCBI
Lrrc7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542321,769,366 - 22,269,781 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542321,764,046 - 22,269,590 (-)NCBIChiLan1.0ChiLan1.0
LRRC7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21156,729,554 - 157,306,887 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11155,889,299 - 156,466,539 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0168,802,557 - 69,359,159 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1170,792,893 - 71,345,038 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl170,794,254 - 71,343,917 (+)Ensemblpanpan1.1panPan2
LRRC7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1675,578,651 - 75,964,171 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl675,580,515 - 75,964,156 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha678,192,058 - 78,683,655 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0676,172,143 - 76,670,419 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl676,170,136 - 76,671,316 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1675,723,968 - 76,216,099 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0675,619,437 - 76,117,489 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0676,120,686 - 76,612,920 (-)NCBIUU_Cfam_GSD_1.0
Lrrc7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505882,071,931 - 82,603,512 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365911,900,334 - 2,416,912 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365911,905,434 - 2,417,053 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6142,735,890 - 143,274,231 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16142,735,676 - 143,273,992 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26132,308,495 - 132,436,571 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRRC7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12063,016,441 - 63,567,809 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2063,018,105 - 63,565,817 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603354,048,609 - 54,605,591 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrrc7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474225,863,434 - 26,243,376 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474225,849,355 - 26,384,417 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lrrc7
12920 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:50
Interacting mature miRNAs:53
Transcripts:ENSMUST00000106044
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142245Pstc1_mperiosteal circumference 1 (mouse)Not determined3126270248159745316Mouse
1301218Letohc1_mlow ethanol consumption 1 (mouse)Not determined3126352986159745316Mouse
1301347Fpli_mfasting plasma insulin (mouse)Not determined3126460514159745316Mouse
1301563Alcp3_malcohol preference locus 3 (mouse)Not determined3130736935159745316Mouse
11039523Tbbr1_mTrypanosoma brucei brucei response 1 (mouse)3130849375159745316Mouse
1301528Loco1_mlocomotor activity 1 (mouse)Not determined3133461893159745316Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001081358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001370781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001370782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017319582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003954326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC102540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC118595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC134449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC145301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI853328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB274541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE992834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000106044   ⟹   ENSMUSP00000101659
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3157,790,076 - 158,267,858 (-)Ensembl
GRCm38.p6 Ensembl3158,084,439 - 158,562,221 (-)Ensembl
RefSeq Acc Id: ENSMUST00000197866
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3158,116,776 - 158,266,982 (-)Ensembl
GRCm38.p6 Ensembl3158,411,139 - 158,561,345 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198284
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3158,157,970 - 158,266,973 (-)Ensembl
GRCm38.p6 Ensembl3158,452,333 - 158,561,336 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199890   ⟹   ENSMUSP00000142440
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3157,789,303 - 158,267,771 (-)Ensembl
GRCm38.p6 Ensembl3158,083,666 - 158,562,134 (-)Ensembl
RefSeq Acc Id: ENSMUST00000200137   ⟹   ENSMUSP00000142498
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3157,788,532 - 158,267,858 (-)Ensembl
GRCm38.p6 Ensembl3158,082,895 - 158,562,221 (-)Ensembl
RefSeq Acc Id: ENSMUST00000200196   ⟹   ENSMUSP00000143365
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3157,788,528 - 158,059,070 (-)Ensembl
GRCm38.p6 Ensembl3158,082,891 - 158,353,433 (-)Ensembl
RefSeq Acc Id: ENSMUST00000200255
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3157,772,823 - 157,781,749 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238317   ⟹   ENSMUSP00000158628
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3157,789,303 - 158,267,771 (-)Ensembl
GRCm38.p6 Ensembl3158,083,666 - 158,562,134 (-)Ensembl
RefSeq Acc Id: NM_001081358   ⟹   NP_001074827
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,788,528 - 158,267,398 (-)NCBI
GRCm383158,067,186 - 158,561,761 (-)NCBI
MGSCv373157,747,403 - 158,225,185 (-)RGD
Celera3164,550,251 - 165,021,656 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001291452   ⟹   NP_001278381
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,788,528 - 158,267,398 (-)NCBI
GRCm383158,067,186 - 158,561,761 (-)NCBI
Celera3164,550,251 - 165,021,656 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001291453   ⟹   NP_001278382
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,788,528 - 158,267,398 (-)NCBI
GRCm383158,067,186 - 158,561,761 (-)NCBI
Celera3164,550,251 - 165,021,656 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001370781   ⟹   NP_001357710
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,772,823 - 158,267,398 (-)NCBI
GRCm383158,067,186 - 158,561,761 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001370782   ⟹   NP_001357711
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,772,823 - 158,267,398 (-)NCBI
GRCm383158,067,186 - 158,561,761 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501504   ⟹   XP_006501567
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,088,154 (-)NCBI
GRCm383158,069,460 - 158,364,028 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501505   ⟹   XP_006501568
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,268,056 (-)NCBI
GRCm383158,069,460 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501507   ⟹   XP_006501570
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,268,056 (-)NCBI
GRCm383158,084,514 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501508   ⟹   XP_006501571
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,268,056 (-)NCBI
GRCm383158,069,460 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501510   ⟹   XP_006501573
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,268,056 (-)NCBI
GRCm383158,069,460 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501511   ⟹   XP_006501574
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,268,056 (-)NCBI
GRCm383158,069,460 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501512   ⟹   XP_006501575
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,268,056 (-)NCBI
GRCm383158,069,460 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011240122   ⟹   XP_011238424
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,266,815 (-)NCBI
GRCm383158,069,460 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011240123   ⟹   XP_011238425
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,059,038 (-)NCBI
GRCm383158,069,460 - 158,263,389 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011240124   ⟹   XP_011238426
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 157,885,420 (-)NCBI
GRCm383158,069,460 - 158,179,783 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017319582   ⟹   XP_017175071
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,268,056 (-)NCBI
GRCm383158,069,868 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252621   ⟹   XP_030108481
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,267,446 (-)NCBI
GRCm383158,069,460 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252622   ⟹   XP_030108482
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,869,918 - 158,268,056 (-)NCBI
GRCm383158,164,281 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252624   ⟹   XP_030108484
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,268,056 (-)NCBI
GRCm383158,069,460 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036163108   ⟹   XP_036019001
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 158,268,056 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036163109   ⟹   XP_036019002
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,775,505 - 157,885,433 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003954326
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,832,852 - 158,268,056 (-)NCBI
GRCm383158,127,215 - 158,561,983 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004941322
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,866,458 - 158,268,056 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004941323
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,854,310 - 158,268,056 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004941324
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,854,310 - 158,268,056 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004941325
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,903,754 - 158,268,254 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004941326
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393157,903,754 - 158,267,446 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001074827 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278381 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278382 (Get FASTA)   NCBI Sequence Viewer  
  NP_001357710 (Get FASTA)   NCBI Sequence Viewer  
  NP_001357711 (Get FASTA)   NCBI Sequence Viewer  
  XP_006501567 (Get FASTA)   NCBI Sequence Viewer  
  XP_006501568 (Get FASTA)   NCBI Sequence Viewer  
  XP_006501570 (Get FASTA)   NCBI Sequence Viewer  
  XP_006501571 (Get FASTA)   NCBI Sequence Viewer  
  XP_006501573 (Get FASTA)   NCBI Sequence Viewer  
  XP_006501574 (Get FASTA)   NCBI Sequence Viewer  
  XP_006501575 (Get FASTA)   NCBI Sequence Viewer  
  XP_011238424 (Get FASTA)   NCBI Sequence Viewer  
  XP_011238425 (Get FASTA)   NCBI Sequence Viewer  
  XP_011238426 (Get FASTA)   NCBI Sequence Viewer  
  XP_017175071 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108481 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108482 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108484 (Get FASTA)   NCBI Sequence Viewer  
  XP_036019001 (Get FASTA)   NCBI Sequence Viewer  
  XP_036019002 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI38451 (Get FASTA)   NCBI Sequence Viewer  
  BAC65780 (Get FASTA)   NCBI Sequence Viewer  
  BAE24769 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000101659
  ENSMUSP00000101659.2
  ENSMUSP00000142440
  ENSMUSP00000142440.2
  ENSMUSP00000142498
  ENSMUSP00000142498.2
  ENSMUSP00000143365
  ENSMUSP00000143365.2
  ENSMUSP00000158628
  ENSMUSP00000158628.3
GenBank Protein Q80TE7 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001074827   ⟸   NM_001081358
- Peptide Label: isoform 1
- UniProtKB: E9Q6L9 (UniProtKB/TrEMBL),   A0A0G2JFZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006501567   ⟸   XM_006501504
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JFZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006501575   ⟸   XM_006501512
- Peptide Label: isoform X9
- UniProtKB: A0A0G2JFZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006501573   ⟸   XM_006501510
- Peptide Label: isoform X5
- UniProtKB: A0A0G2JFZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006501571   ⟸   XM_006501508
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JFZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006501574   ⟸   XM_006501511
- Peptide Label: isoform X6
- UniProtKB: Q80TE7 (UniProtKB/Swiss-Prot),   A0A571BEA5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006501568   ⟸   XM_006501505
- Peptide Label: isoform X2
- UniProtKB: Q80TE7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006501570   ⟸   XM_006501507
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JFZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278382   ⟸   NM_001291453
- Peptide Label: isoform 3
- UniProtKB: Q80TE7 (UniProtKB/Swiss-Prot),   B9EHV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278381   ⟸   NM_001291452
- Peptide Label: isoform 2
- UniProtKB: Q80TE7 (UniProtKB/Swiss-Prot),   A0A0G2JDT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011238425   ⟸   XM_011240123
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_011238426   ⟸   XM_011240124
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_011238424   ⟸   XM_011240122
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JFZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017175071   ⟸   XM_017319582
- Peptide Label: isoform X8
- UniProtKB: Q80TE7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001357711   ⟸   NM_001370782
- Peptide Label: isoform 5
- UniProtKB: Q80TE7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001357710   ⟸   NM_001370781
- Peptide Label: isoform 4
- UniProtKB: A0A0G2JFZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030108484   ⟸   XM_030252624
- Peptide Label: isoform X15
- UniProtKB: Q80TE7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_030108481   ⟸   XM_030252621
- Peptide Label: isoform X10
- UniProtKB: A0A0G2JFZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030108482   ⟸   XM_030252622
- Peptide Label: isoform X14
RefSeq Acc Id: ENSMUSP00000142440   ⟸   ENSMUST00000199890
RefSeq Acc Id: ENSMUSP00000158628   ⟸   ENSMUST00000238317
RefSeq Acc Id: ENSMUSP00000101659   ⟸   ENSMUST00000106044
RefSeq Acc Id: ENSMUSP00000143365   ⟸   ENSMUST00000200196
RefSeq Acc Id: ENSMUSP00000142498   ⟸   ENSMUST00000200137
RefSeq Acc Id: XP_036019001   ⟸   XM_036163108
- Peptide Label: isoform X7
- UniProtKB: Q80TE7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_036019002   ⟸   XM_036163109
- Peptide Label: isoform X13
Protein Domains
PDZ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80TE7-F1-model_v2 AlphaFold Q80TE7 1-1490 view protein structure

Promoters
RGD ID:6834044
Promoter ID:MM_KWN:36516
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_001081358,   UC008RVX.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363158,224,926 - 158,225,426 (-)MPROMDB
RGD ID:6882710
Promoter ID:EPDNEW_M4805
Type:initiation region
Name:Lrrc7_1
Description:Mus musculus leucine rich repeat containing 7 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4806  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383158,561,754 - 158,561,814EPDNEW
RGD ID:6882712
Promoter ID:EPDNEW_M4806
Type:initiation region
Name:Lrrc7_2
Description:Mus musculus leucine rich repeat containing 7 , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4805  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383158,562,222 - 158,562,282EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676665 AgrOrtholog
Ensembl Genes ENSMUSG00000028176 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSG00000104597 Ensembl
Ensembl Transcript ENSMUST00000106044 ENTREZGENE
  ENSMUST00000106044.6 UniProtKB/TrEMBL
  ENSMUST00000199890 ENTREZGENE
  ENSMUST00000199890.5 UniProtKB/TrEMBL
  ENSMUST00000200137 ENTREZGENE
  ENSMUST00000200137.5 UniProtKB/TrEMBL
  ENSMUST00000200196 ENTREZGENE
  ENSMUST00000200196.5 UniProtKB/TrEMBL
  ENSMUST00000238317 ENTREZGENE
  ENSMUST00000238317.3 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:242274 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2676665 ENTREZGENE
NCBI Gene 242274 ENTREZGENE
PANTHER DISCS LARGE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LEUCINE-RICH REPEAT-CONTAINING PROTEIN 7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lrrc7 PhenoGen
PROSITE LRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LRR_BAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_SD22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_TYP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Outer arm dynein light chain 1 UniProtKB/TrEMBL
  RNI-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JDT9 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JFZ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A571BEA5 ENTREZGENE, UniProtKB/TrEMBL
  B9EHV0 ENTREZGENE, UniProtKB/TrEMBL
  E9Q6L9 ENTREZGENE, UniProtKB/TrEMBL
  LRRC7_MOUSE UniProtKB/Swiss-Prot
  Q3URB9_MOUSE UniProtKB/TrEMBL
  Q80TE7 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-01-11 Lrrc7  leucine rich repeat containing 7  B230334C09Rik  RIKEN cDNA B230334C09 gene  Data Merged 737654 PROVISIONAL