N4bp2l2 (NEDD4 binding protein 2-like 2) - Rat Genome Database

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Gene: N4bp2l2 (NEDD4 binding protein 2-like 2) Rattus norvegicus
Analyze
Symbol: N4bp2l2
Name: NEDD4 binding protein 2-like 2
RGD ID: 1359603
Description: Predicted to enable enzyme binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of hematopoietic stem cell differentiation; negative regulation of transcription by RNA polymerase II; and positive regulation of hematopoietic stem cell proliferation. Predicted to act upstream of or within blastocyst development. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Orthologous to human N4BP2L2 (NEDD4 binding protein 2 like 2); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100909860; MGC94223; NEDD4-binding protein 2-like 2; phosphonoformate immuno-associated protein 5 homolog; similar to hypothetical protein from BCRA2 region; uncharacterized LOC100909860; uncharacterized protein LOC100909860
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8124,972,967 - 5,038,027 (-)NCBIGRCr8
mRatBN7.212137,342 - 200,292 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl12103,590 - 197,784 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx12706,021 - 768,933 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0121,228,260 - 1,291,179 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.012127,903 - 190,623 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.012627,128 - 650,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl12628,488 - 650,376 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.012611,943 - 635,074 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4124,184,417 - 4,205,550 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1124,184,416 - 4,205,549 (+)NCBI
Celera121,887,059 - 1,908,425 (-)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
chlorpyrifos  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
imidacloprid  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
testosterone enanthate  (ISO)
thapsigargin  (ISO)
theophylline  (ISO)
thiabendazole  (EXP)
thimerosal  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA,ISO,ISS)
transcription repressor complex  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:18360097   PMID:19056867   PMID:19506020  


Genomics

Comparative Map Data
N4bp2l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8124,972,967 - 5,038,027 (-)NCBIGRCr8
mRatBN7.212137,342 - 200,292 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl12103,590 - 197,784 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx12706,021 - 768,933 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0121,228,260 - 1,291,179 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.012127,903 - 190,623 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.012627,128 - 650,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl12628,488 - 650,376 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.012611,943 - 635,074 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4124,184,417 - 4,205,550 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1124,184,416 - 4,205,549 (+)NCBI
Celera121,887,059 - 1,908,425 (-)NCBICelera
Cytogenetic Map12p12NCBI
N4BP2L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381332,432,485 - 32,538,868 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1332,432,417 - 32,538,885 (-)EnsemblGRCh38hg38GRCh38
GRCh371333,006,622 - 33,113,005 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361331,904,930 - 32,010,936 (-)NCBINCBI36Build 36hg18NCBI36
Celera1314,073,721 - 14,179,731 (-)NCBICelera
Cytogenetic Map13q13.1NCBI
HuRef1313,818,368 - 13,923,753 (-)NCBIHuRef
CHM1_11332,974,162 - 33,080,564 (-)NCBICHM1_1
T2T-CHM13v2.01331,649,729 - 31,756,133 (-)NCBIT2T-CHM13v2.0
N4bp2l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395150,515,310 - 150,589,213 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5150,531,472 - 150,589,648 (-)EnsemblGRCm39 Ensembl
GRCm385150,599,931 - 150,665,748 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5150,608,007 - 150,666,183 (-)EnsemblGRCm38mm10GRCm38
MGSCv375151,438,548 - 151,468,187 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365150,916,589 - 150,933,956 (-)NCBIMGSCv36mm8
Celera5148,640,440 - 148,670,079 (-)NCBICelera
Cytogenetic Map5G3NCBI
N4bp2l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543113,314,075 - 13,418,090 (+)NCBIChiLan1.0ChiLan1.0
N4BP2L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21431,998,173 - 32,106,760 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11323,105,030 - 23,213,013 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01313,691,326 - 13,803,162 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11332,133,618 - 32,231,146 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1332,133,603 - 32,231,003 (-)Ensemblpanpan1.1panPan2
N4BP2L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1257,622,032 - 7,694,396 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl257,623,670 - 7,694,398 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha257,651,935 - 7,724,601 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0257,718,162 - 7,791,082 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl257,718,103 - 7,790,814 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1257,618,218 - 7,691,056 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0257,616,390 - 7,689,291 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0257,673,686 - 7,746,570 (+)NCBIUU_Cfam_GSD_1.0
N4bp2l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945168,816,704 - 168,905,434 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647227,045,052 - 27,134,170 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
N4BP2L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1118,891,053 - 8,997,810 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2118,713,909 - 8,737,772 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103214263
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1311,191,215 - 11,287,434 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl311,197,302 - 11,285,607 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605733,065,334 - 33,161,891 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
N4bp2l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247765,295,054 - 5,467,454 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in N4bp2l2
125 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:22
Count of miRNA genes:22
Interacting mature miRNAs:22
Transcripts:ENSRNOT00000001468
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)1219318387Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat

Markers in Region
RH130841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.212196,642 - 196,829 (+)MAPPERmRatBN7.2
Rnor_6.012646,961 - 647,147NCBIRnor6.0
Rnor_5.012631,230 - 631,416UniSTSRnor5.0
RGSC_v3.4124,187,436 - 4,187,622UniSTSRGSC3.4
Celera121,904,915 - 1,905,101UniSTS
Cytogenetic Map12p12UniSTS
RH131153  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.212178,912 - 179,129 (+)MAPPERmRatBN7.2
Rnor_6.012628,627 - 628,843NCBIRnor6.0
Rnor_5.012613,442 - 613,658UniSTSRnor5.0
RGSC_v3.4124,205,194 - 4,205,410UniSTSRGSC3.4
Celera121,887,199 - 1,887,415UniSTS
Cytogenetic Map12p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 10 74 35 41 11 8
Low 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001468   ⟹   ENSRNOP00000001468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl12170,056 - 197,784 (-)Ensembl
Rnor_6.0 Ensembl12628,488 - 650,376 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111844   ⟹   ENSRNOP00000081414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl12137,355 - 197,784 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116179   ⟹   ENSRNOP00000078717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl12145,065 - 197,784 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118063   ⟹   ENSRNOP00000088209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl12103,590 - 197,784 (-)Ensembl
RefSeq Acc Id: NM_001005533   ⟹   NP_001005533
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,014,389 - 5,035,676 (-)NCBI
mRatBN7.212178,766 - 200,055 (-)NCBI
Rnor_6.012628,487 - 650,376 (-)NCBI
Rnor_5.012611,943 - 635,074 (-)NCBI
RGSC_v3.4124,184,417 - 4,205,550 (+)RGD
Celera121,887,059 - 1,908,425 (-)RGD
Sequence:
RefSeq Acc Id: NM_001400958   ⟹   NP_001387887
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8124,972,967 - 5,035,676 (-)NCBI
mRatBN7.212137,342 - 200,055 (-)NCBI
RefSeq Acc Id: XM_006248735   ⟹   XP_006248797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8124,980,392 - 5,035,862 (-)NCBI
mRatBN7.212144,766 - 200,259 (-)NCBI
Rnor_6.012627,128 - 650,280 (-)NCBI
Rnor_5.012611,943 - 635,074 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089150   ⟹   XP_038945078
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,014,396 - 5,035,858 (-)NCBI
mRatBN7.212171,721 - 200,255 (-)NCBI
RefSeq Acc Id: XM_039089151   ⟹   XP_038945079
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8124,972,967 - 5,035,910 (-)NCBI
mRatBN7.212137,342 - 200,292 (-)NCBI
RefSeq Acc Id: XM_039089152   ⟹   XP_038945080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,014,396 - 5,032,313 (-)NCBI
mRatBN7.212137,342 - 196,693 (-)NCBI
RefSeq Acc Id: XM_063271110   ⟹   XP_063127180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8124,972,967 - 5,038,027 (-)NCBI
RefSeq Acc Id: XM_063271111   ⟹   XP_063127181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8124,972,967 - 5,038,027 (-)NCBI
RefSeq Acc Id: XM_063271112   ⟹   XP_063127182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,014,396 - 5,036,163 (-)NCBI
RefSeq Acc Id: XM_063271113   ⟹   XP_063127183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,014,396 - 5,038,027 (-)NCBI
RefSeq Acc Id: XM_063271114   ⟹   XP_063127184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8124,972,967 - 5,032,496 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001005533   ⟸   NM_001005533
- Peptide Label: isoform 2
- UniProtKB: Q66H65 (UniProtKB/Swiss-Prot),   A0A8I5ZLI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248797   ⟸   XM_006248735
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZSH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000001468   ⟸   ENSRNOT00000001468
RefSeq Acc Id: XP_038945079   ⟸   XM_039089151
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AIC7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945080   ⟸   XM_039089152
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038945078   ⟸   XM_039089150
- Peptide Label: isoform X5
- UniProtKB: A6KSV3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000088209   ⟸   ENSRNOT00000118063
RefSeq Acc Id: ENSRNOP00000078717   ⟸   ENSRNOT00000116179
RefSeq Acc Id: ENSRNOP00000081414   ⟸   ENSRNOT00000111844
RefSeq Acc Id: NP_001387887   ⟸   NM_001400958
- Peptide Label: isoform 1
RefSeq Acc Id: XP_063127181   ⟸   XM_063271111
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063127180   ⟸   XM_063271110
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063127184   ⟸   XM_063271114
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063127183   ⟸   XM_063271113
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063127182   ⟸   XM_063271112
- Peptide Label: isoform X6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H65-F1-model_v2 AlphaFold Q66H65 1-574 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698358
Promoter ID:EPDNEW_R8883
Type:initiation region
Name:N4bp2l2_1
Description:NEDD4 binding protein 2-like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.012650,371 - 650,431EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359603 AgrOrtholog
BioCyc Gene G2FUF-20523 BioCyc
Ensembl Genes ENSRNOG00000001108 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001468 ENTREZGENE
  ENSRNOT00000001468.6 UniProtKB/Swiss-Prot
  ENSRNOT00000111844.1 UniProtKB/TrEMBL
  ENSRNOT00000116179.1 UniProtKB/TrEMBL
  ENSRNOT00000118063.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131024 IMAGE-MGC_LOAD
InterPro NEDD4_b_p2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:288416 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94223 IMAGE-MGC_LOAD
NCBI Gene 288416 ENTREZGENE
PANTHER PTHR13308 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13308:SF23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AAA_33 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen N4bp2l2 PhenoGen
RatGTEx ENSRNOG00000001108 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZLI8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZSH6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AIC7 ENTREZGENE, UniProtKB/TrEMBL
  A6KSV3 ENTREZGENE, UniProtKB/TrEMBL
  N42L2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 N4bp2l2  NEDD4 binding protein 2-like 2  LOC100909860  uncharacterized LOC100909860  Data merged from RGD:6501161 737654 PROVISIONAL
2012-07-05 LOC100909860  uncharacterized LOC100909860      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-06 N4bp2l2  NEDD4 binding protein 2-like 2  MGC94223  similar to hypothetical protein from BCRA2 region  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 MGC94223  similar to hypothetical protein from BCRA2 region      Symbol and Name status set to provisional 70820 PROVISIONAL