Gene: Pdhb (pyruvate dehydrogenase E1 beta subunit) Rattus norvegicus
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Symbol: Pdhb
Name: pyruvate dehydrogenase E1 beta subunit
Description: ENCODES a protein that exhibits pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase (NAD+) activity (ortholog); pyruvate dehydrogenase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate; tricarboxylic acid cycle (ortholog); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria disease pathway; Leigh syndrome pathway; ASSOCIATED WITH Carcinoma, Renal Cell (ortholog); pyruvate decarboxylase deficiency (ortholog); Pyruvate Dehydrogenase Complex Deficiency Disease (ortholog); FOUND IN mitochondrion; pyruvate dehydrogenase complex; extracellular exosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; aflatoxin B1
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC94149; PDHE1-B; pyruvate dehydrogenase (lipoamide) beta; pyruvate dehydrogenase E1 component subunit beta, mitochondrial
Orthologs:
Homo sapiens (human) : PDHB (pyruvate dehydrogenase E1 beta subunit)  HGNC  AGR
Mus musculus (house mouse) : Pdhb (pyruvate dehydrogenase (lipoamide) beta)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Pdhb (pyruvate dehydrogenase E1 beta subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : PDHB (pyruvate dehydrogenase E1 beta subunit)
Canis lupus familiaris (dog) : PDHB (pyruvate dehydrogenase E1 beta subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdhb (pyruvate dehydrogenase E1 beta subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01518,540,826 - 18,546,855 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01522,507,861 - 22,513,890 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41518,737,449 - 18,743,391 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11518,737,448 - 18,743,390 (+)NCBI
Celera1516,710,789 - 16,716,731 (+)NCBI
Cytogenetic Map15p14NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pdhb
AGR Gene
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 1359146
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE