Gene: Pdhb (pyruvate dehydrogenase (lipoamide) beta) Rattus norvegicus
Symbol: Pdhb
Name: pyruvate dehydrogenase (lipoamide) beta
Description: ENCODES a protein that exhibits pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate; tricarboxylic acid cycle (ortholog); PARTICIPATES IN pyruvate metabolic pathway; butanoate metabolic pathway; citric acid cycle pathway; ASSOCIATED WITH Pyruvate Dehydrogenase Complex Deficiency Disease (ortholog); Pyruvate Dehydrogenase E1-Beta Deficiency (ortholog); FOUND IN mitochondrion; pyruvate dehydrogenase complex; extracellular exosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; aflatoxin B1
Type: protein-coding
Also known as: MGC94149; PDHE1-B; pyruvate dehydrogenase E1 component subunit beta, mitochondrial
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01518,540,826 - 18,546,855+NCBI
Rat Cytogenetic Map15p14 NCBI
RGSC Genome Assembly v5.01522,507,861 - 22,513,890+NCBI
RGSC Genome Assembly v3.41518,737,449 - 18,743,391+NCBI
Rat Celera Assembly1516,710,789 - 16,716,731+NCBI
Genome Assembly 3.11518,737,448 - 18,743,390+NCBI

Launch Genome Browser (GBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Pdhb
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1359146
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE